We previously covered the management of young febrile infants in a 2017 podcast but now we have updated guidance from the AAP. In this podcast, we review the 2021 AAP Guidelines for the management of well-appearing febrile infants 8-60 days old, highlight practice-changing recommendations. Show notes/references: FOAMcast.org Thanks for listening! Lauren Westafer...
In this episode, Jeremy discusses what we know about breakthrough infections in the delta variant era and what this may mean for COVID-19 vaccine boosters. Jeremy's takes can be found at Inside Medicine Show notes/references: FOAMcast.org Thanks for listening! Lauren Westafer and Jeremy Faust
In this episode, we discuss the current evidence (as of September 24, 2021) on COVID-19 vaccine boosters as well as the CDC recommendations and the details of the Advisory Council on Immunization Practices recommendations/vote. Show notes/References at FOAMcast.org Jeremy's takes can be found at Inside Medicine Thanks for listening! Lauren Westafer and Jeremy Faust
In this literature update podcast covering important papers of 2021, we cover Becattini et al on the assessment of right ventricular dysfunction in patients diagnosed with acute pulmonary embolism (PE). We review guidelines on PE risk stratification for severity and discuss this individual patient meta-analysis. Show notes/references: FOAMcast.org Thanks for listening! Lauren Westafer and Jeremy Faust...
This is a quick literature update on practice-changing literature from 2021. Here we discuss Pappal et al in Annals of Emergency Medicine on awareness during paralysis in mechanically ventilated patients Show notes / References: FOAMcast.org Thanks for listening! Lauren Westafer and Jeremy Faust
This is a quick literature update of important literature in 2021 covering take-home naloxone by Kilaru et al . In this episode, we discuss principles of harm reduction, including naloxone, as well as the study. Show notes, references, and resources: FOAMcast.org Thanks for listening! Lauren Westafer and Jeremy Faust
We review new clinical policy guidelines from SAEM on patients with recurrent (2 ED evaluations in 12 months) low risk (e.g. HEART score <4) chest pain. Show notes and references: FOAMcast.org Thanks for listening! Jeremy Faust and Lauren Westafer
In this episode, we review the data on the association between myocarditis and the mRNA COVID-19 vaccines. Show notes / References: FOAMcast.org Thanks for listening! Jeremy Faust and Lauren Westafer
In this quick literature update, we review a recent paper by Branch et al on early 'panscan' (head to pelvis CT scan ) in patients with return of spontaneous circulation after out of hospital cardiac arrest. Show notes/ references: FOAMcast.org Thanks for listening! Lauren Westafer and Jeremy Faust
In this episode we review what we know about vaccine induced thrombotic thrombocytopenia (VITT), which has been associated with the COVID-19 viral vector vaccines by AstraZeneca and Johnson & Johnson. Show notes/references: FOAMcast.org Thanks for listening! Lauren Westafer and Jeremy Faust
In this podcast, we review Cerebral Vein Thrombosis (CVT) including clinical presentation, diagnosis, and management. Show notes: FOAMcast.org Thanks for listening! Lauren Westafer and Jeremy Faust
In this episode, we discuss ivermectin as a potential therapeutic for COVID-19 and review available randomized trials evaluating this drug. Chaccour et al E-Clinical Medicine Lopez-Medina et al. JAMA Schwartz et al (not yet published) IDSA guidelines NIH Treatment guidelines Show notes: FOAMcast.org Thanks for listening! Jeremy Faust and Lauren Westafer...
In this episode, we review new registry data from the ACIP meeting on pregnant people who received an mRNA COVID-19 vaccine and discuss, in general, what we know about the COVID-19 vaccines in pregnancy. Show notes: FOAMcast.org Pregnancy Decision Aid Thanks for listening! Lauren Westafer and Jeremy Faust...
In this episode, we review the FDA briefing document on the Janssen (Johnson & Johnson) viral vector COVID-19 vaccine. Show notes: FOAMcast.org Thanks for listening! Lauren Westafer & Jeremy Faust
We have previously covered epistaxis on FOAMcast , including the use of tranexamic acid (TXA). Now, we cover a new, large RCT, the NoPac trial by Reuben et al, on TXA for epistaxis. Show notes: FOAMcast.org Thanks for listening! Lauren Westafer and Jeremy Faust
There's been a lot of excitement over various drugs for COVID-19, including anti-inflammatory drugs. Colchicine, a medication long used for gout, fits that bill. In this podcast, we review 3 trials of colchicine including COLCORONA , GRECCO-19 , and a study by Lopes et al . Show notes: FOAMcast.org Thanks for listening! Jeremy Faust and Lauren Westafer...
Early studies of tocilizumab, a monoclonal antibody that binds interleukin-6 , were disappointing. However, the REMAP-CAP trial recently reported a benefit to tocilizumab in non-critically ill hospitalized patients with COVID-19. Now, from the RECOVERY trial (the trial that brought us dexamethasone), we have more good news for tocilizumab - which we cover in this podcast Show notes: FOAMcast.org Thanks for listening! Lauren Westafer and Jeremy Faust...
As vaccinations role out, the news of SARS-CoV-2 variants with mutations to the spike protein have dominated news cycles. One unanswered question has been - do the current vaccines protect against these variants? We tackle this issue and look at a new paper [pre-print] by Wu et al .
Prior randomized trials of convalescent plasma in COVID-19 have had disappointing results. However, these trials included patients with severe illness who were many days (if not weeks) into the course of their illness. To date, it was hypothesized, but unknown, that the benefit would be in patients very early in the course of their illness. We cover an RCT by Libster et al in NEJM on convalescent plasma in older patients with mild COVID-19. Show notes/references: FOAMcast.org Thanks for listenin...
In this quick literature update we review the new recommendations from the CDC for the treatment of gonococcal infections which include: Higher dose ceftriaxone (500 mg IM) or 1 gm IM if ≥150 kg patient No routine azithromycin Preference for doxycycline for co-treatment of presumed chlamydial infection Show notes and references: FOAMcast.org Thanks for listening! Lauren Westafer and Jeremy Faust...
For years studies have questioned whether pulse oximeters perform as well in non-White patients as in White patients. This is particularly important now as disposition decisions in patients with COVID-19 are often made based on pulse oximetry readings. We discussed an article by Sjoding et al in NEJM Show notes at FOAMcast.org Thanks for listening! Lauren Westafer and Jeremy Faust...
Despite multiple Phase II/III vaccine trials of >30,000 participants, pregnant patients or those who are lactating have been largely excluded. In this podcast, we cover what we know (and what we don't know thus far). The Pfizer BNT162b2 trial data submitted for FDA Emergency Use Authorization does include information on a minuscule number of patients who were immunized and became pregnant. The Society for Maternal and Fetal Medicine has released statements on vaccines in SARS-CoV-2. In the Un...
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19. * Our understanding of COVID-19 is rapidly developing and this may be out of date in days/weeks. So, check back for updates/fact check what you hea r* Vaccines for SARS-CoV-2 have been in development for only a few months, but several have published early results from Phase III efficacy trials in press releases. In this episode, we review these vaccines and what we know about them, and what we know about them Show note...
In this episode, we review cannabinoid hyperemesis syndrome and two recent randomized controlled trials on treatments Haloperidol - Ruberto et al (Annals of Emergency Medicine, In Press) Capsaicin - Dean et al. Acad Emerg Med 2020. Show notes (references, graphics) at FOAMcast.org Thanks for listening! Jeremy Faust and Lauren Westafer...
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19. * Our understanding of COVID-19 is rapidly developing and this may be out of date in days/weeks. So, check back for updates/fact check what you hea r* Monoclonal antibodies have received significant attention over the past month and we previously podcasted on antibodies that target SARS-CoV-2. In this episode, we review several recent studies on a different "mab", tocilizumab, which targets inflammation mediated by int...
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19. * Our understanding of COVID-19 is rapidly developing and this may be out of date in days/weeks. So, check back for updates/fact check what you hea r* Monoclonal antibodies have received significant attention over the past couple of weeks. In this episode, we review what we know, as of October 9, 2020, about monoclonal antibodies as a therapy for COVID-19. Show notes (references/graphics): FOAMcast.org Thanks for liste...
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19. * Our understanding of COVID-19 is rapidly developing and this may be out of date in days/weeks. So, check back for updates/fact check what you hea r* We review a retrospective evaluation of COVID-19 infections in employees after a protocol that increased the use of high flow nasal cannula ( Westafer et al ) Show notes (references/graphics): FOAMcast.org Thanks for listening, Lauren Westafer and Jeremy Faust...
We spoonfeed you a new article on risk stratification of pulmonary embolism (with critical appraisal pearls!) In this episode, we review a new trial by Barnes et al on antacids versus antacids with lidocaine for epigastric pain and dyspepsia Show notes and references at FOAMcast.org Thanks for listening, Lauren Westafer and Jeremy Faust
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19. * Our understanding of COVID-19 is rapidly developing and this may be out of date in days/weeks. So, check back for updates/fact check what you hea r* We review a new meta-analysis from the WHO REACT group of steroids in critically ill patients with COVID-19 and 3 new randomized trials of steroids in COVID-19 published in JAMA on September 2: REMAP-CAP COVID-19 CoDEX CAPE Covid Show notes (references/graphics): FOAMcas...
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19. * Our understanding of COVID-19 is rapidly developing and this may be out of date in days/weeks. So, check back for updates/fact check what you hea r* We review the evidence, to date, on convalescent plasma for the treatment of COVID-19. This includes 3 randomized trials, as well the US experience with >35,000 patients treated with convalescent plasma, a noncontrolled study by Joyner et al [pre-print]. Show notes (r...
