🦠Microbes, Mutations, and Malignancy: Unveiling the Gut–Blood Cancer Axis 💉
May 11, 2025•4 min
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Episode description
🧬 A molecule from aging gut bacteria—ADP-heptose—enters the bloodstream, activates ALPK1, and triggers NF-κB signaling, driving the expansion of mutant blood stem cells. 🦠🧓
This discovery links gut health to leukemia risk and reveals new targets like ALPK1 and UBE2N for cancer prevention. 💥🩸
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