🫁💥 “Lung Clues & Blood Blues: How Tiny Lung Vesicles Spark Deadly Cancer Clots” 🧬🩸
Apr 19, 2025•3 min
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Episode description
🩸 Summary:
Lung interstitial macrophages, activated by tumor-derived CXCL13, release integrin β2⁺ extracellular vesicles (sEVs) 🧬 that bind platelet GPIb 🧲, triggering clot formation across the body.
These sEVs are both a driver of cancer-associated thrombosis and a potential biomarker for early risk detection 🎯, offering safer, targeted therapeutic opportunities 💉.
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