022 - DAPT: além do AAS e Clopidogrel na síndrome coronariana aguda - podcast episode cover

022 - DAPT: além do AAS e Clopidogrel na síndrome coronariana aguda

Feb 17, 202228 min
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Episode description

Marcos Meniconi, Maria Julia Souto e Manuela Gomes analisam os fatores que devem influenciar o cardiologista a definir quais antiagregantes plaquetários e quanto tempo de terapia dupla deve ser indicado para o paciente submetido a angioplastia coronária percutânea. Acompanhe para recordar os “landmark trials” e novidades sobre o tema. Minutagem: (01:45): tipos de antiagregantes plaquetários (03:15): resistência genética ao clopidogrel? (05:45): quando o segundo antiagregante deve ser o clopidogrel (07:16): ataque do antiagregante na emergência (12:45): por quanto tempo manter a DAPT? (18:22): da para reduzir o tempo de DAPT? (21:20): o que vem por aí (NEO-MINDSET trial) (23:00): mensagens finais (24:30): resposta aos dozers REFERÊNCIAS: 1. Bittl JA, Baber U, Bradley SM, Wijeysundera DN. Duration of dual antiplatelet therapy: a systematic review for the 2016 ACC/AHA guideline focused update on duration of dual antiplatelet therapy in patients with coronary artery disease. Circulation. 2016;134:e156–e178 2. Mauri L, Kereiakes DJ, Yeh RW, et al. Twelve or 30 months of dual antiplatelet therapy after drug-eluting stents. N Engl J Med. 2014;371(23):2155-2166. 3. Mehta SR, Yusuf S, Peters RJ, et al. Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: the PCI-CURE study. Lancet. 2001;358(9281):527-533.
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