Too many systems or components in a pathology workflow adds complexity and cost. How can we create an elegant end to end solution to enhance workflows, while decreasing both complexity and costs? Our guest is John Wirthlin, CEO of Lumea, a company reimagining pathology - beginning and ending with the patient. We discuss the end-to-end solution in digital pathology. One of the promises of digital pathology is making the pathologist’s workflow more streamlined and more efficient. But can we bring ...
May 07, 2022•32 min
Amidst this digital transformation in pathology the talk seems to be largely centered around whole slide imaging of H&E-stained tissue sections. But what about cytology? Why don't we hear much talk about digital cytology, and what are some of the unique challenges in cytology in terms of going digital. Our guest is Michael Quick, Vice President of Research and Development and Innovation at Hologic. We discuss the history and evolution of cervical cancer screening all the way from pap smears to t...
May 02, 2022•29 min
What is going to surprise us in digital pathology in big ways and in small ways? How can seemingly small changes make a big impact in what we do as pathologists and in the lives of patients? How are we going to make use of the large datasets that we will inevitably be generating through the widescale adoption of digital pathology? Our guest is Louis Culot, General Manager for Genomics and Oncology Informatics at Phillips. We're going to be talking about the current landscape of digital pathology...
Apr 21, 2022•28 min
It's easy to get caught up in the hype surrounding digital pathology. But what is actually involved and going digital? What are the steps involved? We know about scanners and viewing images, of course. But what other pieces of software might be necessary or helpful? Coleman Stavish is co-founder and CTO at Proscia, a leading provider of digital and computational pathology solutions. At Proscia, Coleman works with a team of engineers and scientists who develop enterprise software in use at leadin...
Apr 08, 2022•39 min
NVIDIA is involved in computer graphics, artificial intelligence, computing and processors across variety of industries including gaming, entertainment, finance, and health care. What are the commonalties of all these industries and what lesson from other fields can we apply to healthcare? Our guest is Craig Rhodes EMEA Industry Lead - AI for Healthcare and Life Sciences at NVIDIA. There is the perception that healthcare lags other industries in terms of AI applications. Is this true or is it a ...
Mar 31, 2022•40 min
Our guests are Dr. Garth Bryson Consultant Pathologist and Clinical Director for Laboratory Medicine at the NHS Greater Glasgow and Clyde and Dr. David Harrison, Professor of Pathology from the University of Saint Andrews, and both from ICAIRD - the Industrial Center for Artificial Intelligence Research and Digital Diagnostics a program matching AI solutions and research with health and social care priorities across Scotland. We talk about the long journey of implementing digital pathology in a ...
Mar 25, 2022•43 min
Our guest is one of the giants in the field of digital pathology and image analysis. And if he has seen further than others, he will tell you, it is because he was able to stand on the shoulders of giants as well. His unique multidisciplinary approach has allowed him to breakdown silos and see across the often-artificial barriers and distinctions imposed by academic disciplines and patient treatment paradigms. We're talking with Professor Anant Madabhushi, Director of the Center for Computationa...
Mar 17, 2022•47 min
What have we been waiting for? What's taking so long? Much of the technology surrounding digital pathology has been with us for over 20 years. After fits and starts and initial excitement we've been left with disappointment in the past ten years. But now, it seems like the tide is turning and the digital transformation is here. Our guest is Richard Lash, MD, Chief Medical Officer from Lumea, a company re-imagining pathology by developing a comprehensive end to end workflow. Dr. Lash has had a lo...
Mar 10, 2022•28 min
We've all seen it in science fiction movies and maybe somewhat in consumer tech culture with things like Google glasses, or Pokémon GO. Augmented reality – an enhanced version of the physical world through the use of digital visual elements - does it have a role in digital pathology? Gabe Siegel is the CEO and co-founder of Augmentiqs, a company that develops augmented reality and digital pathology capabilities for the existing microscope. Prior to starting Augmentiqs, Gabe worked for multiple m...
Mar 04, 2022•25 min
In this digital transformation of pathology, much of the focus is, of course, on the imaging of histologic sections or glass slides, which were once viewed under the microscope. It's often easy to forget that the examination of the specimen begins much earlier in the process - in the gross room or even in the operating room. Our guest is Vikram Butani, CEO and founder of Kubtec, whose passion is developing transformative specimen imaging, and specimen radiography systems that enable medical prof...
Feb 25, 2022•22 min
The big trend in oncology over the past few years has been immunotherapy. this trend is converging with the digital transformation we are undergoing in pathology we seem to be at the crossroads of immune-oncology, digital pathology, image analysis, artificial intelligence, and the increasing ability to Multiplex. Our guest is Keith Wharton Jr., MD, PhD from Ultivue, a company looking to reveal actional biology through multiplex immunofluorescence to make immunotherapy a reality for patients with...
Feb 17, 2022•47 min
The Armed Forces Institute of Pathology (AFIP) was in existence from 1862 to 2011. Many of us in pathology know it as the publisher of the “tumor fascicles” or the Atlas of Tumor Pathology series, originating in 1947, as well as a center of consultation and tissue repository unparalleled in the world. The AFIP was reborn as the Joint Pathology Center (JPC), whose mission is to deliver cost-effective, high-quality, multidisciplinary pathology consultation and education; and preserve, modernize, a...
Feb 10, 2022•34 min
We hear that multiple file formats or perhaps, more importantly, lack of a uniform file format seems to be a big issue in digital pathology. Why is this? What do we even mean by a file format? And will we be able to overcome this barrier on the road to full scale adoption of digital pathology? Yves Sucaet, a PhD in Bioinformatics, has a research background in systems and network biology. In 2012, he became intrigued with the idea of applying bioinformatics algorithms to virtualized microscopic m...
Feb 03, 2022•46 min
Imagine a world without staining… in the excitement of digital pathology we often forget that we're using with a legacy system of staining tissue pink and purple, which is time-consuming and tissue-destructive. There's got to be a better way. Our guest is Dr. Gideon Ho, who co-founded HistoIndex to develop and commercialize the world’s first fully automated, quantitative, stain-free imaging system. Under his direction as the CEO, the laser-based stain-free imaging system has been successfully im...
Jan 27, 2022•27 min
What is The State of the Practice of digital pathology as we enter 2022? Where are we in terms of integrated workflows, predictive and prognostic algorithms based on H&E morphology, and incorporating AI into workflows or diagnostic assistance? Perhaps most pressingly, have we finally made the business case for wide scale adoption of digital pathology? Our guest is Michael Feldman, MD, PhD, Professor of Pathology and Laboratory Medicine at the University of Pennsylvania as well as Vice Chair for ...
Jan 20, 2022•34 min
In addition to interpreting patient biopsies and signing out cases, pathologists perform a wide variety of functions - including intraoperative consultation or frozen section, presenting cases at tumor boards or other conferences, doing procedures, or assessing the adequacy from image guided biopsies. This is done in a wide variety of practice settings. Many times, it's done over a very large geographical area where the physical presence of a pathologist may be impractical or highly inconvenient...
Jan 13, 2022•31 min
We welcome back Professor Hamid Tizhoosh from KIMIA Lab and now of the Mayo Clinic. Dr. Tizhoosh was one of our most popular guests from last season. We talked about artificial intelligence, but it seems like we barely scratched the surface. AI is such a hot topic - so before we go any further, we’ll go back to a rough definition of Artificial Intelligence. In Machine learning a theme we keep hearing about is supervised vs. unsupervised learning. What does that mean and why is it important? The ...
Jan 06, 2022•47 min
We all want to do the right thing - but how do we know what that is? What is ethics and what is the difference between ethics and the law? Our guest is Brian Jackson, MD, medical director of IT, business development and support services at ARUP, as well as associate professor of Pathology and adjunct associate professor of biomedical informatics at the University of Utah. We're talking about the foundational principles of ethics in science and medicine. What are the limits of informed consent as...
Dec 02, 2021•40 min
We keep hearing that one of the promises of digital pathology is the ability to develop AI based algorithms and tools that will allow us to do things that we never have before. This gets many people excited in the industry - particularly computer scientists, programmers and machine learning specialists - but what about the role of the pathologist? How can we the keep pathologist engaged in the development of AI algorithms and digital pathology workflows? One of the things that has hindered surgi...
Nov 25, 2021•39 min
Our guest is Michael Valante, Global Business Leader for Dell Technology’s Healthcare Division and Dell’s Chief Technology Officer for Digital Pathology, where he is a subject matter expert in the areas of enterprise imaging and pathology informatics. Mike is deeply focused on the healthcare industry and the intersection of medical imaging and information technology. We’re going to discuss lessons learned from Dell’s involvement in IT infrastructure throughout healthcare and disciplines outside ...
Nov 18, 2021•32 min
Immunotherapy and immune-oncology have become such hot areas of exploration in the past few years. We're going to explore the forces which have coalesced to make this a reality. Our guest is doctor Katir Patel, PhD a scientist with a keen interest in immunotherapy and diagnostics. We're going to be exploring the role of digital pathology in immune-oncology. How will we use the tools in our arsenal, such as image analysis, multiplexing, artificial intelligence and even good old-fashioned H&E sect...
Nov 11, 2021•26 min
There's so much excitement and hype around AI, but what does it mean for the practicing pathologist? Workflows seem very fragmented and antiquated, particularly in this new era of digital pathology. Can we add value in the pre-analytic or specimen handling phase and also in the post-analytic or reporting phase? Our guest is Hillel Kahane, MD, founder of Starpath diagnostics, a renowned and well-respected board certified uropathologist with over 28 years of experience in the commercial USA labora...
Nov 04, 2021•27 min
There is so much rich information imbedded in the histologic and molecular features of tissue sections which can be extracted through digital pathology. We seem to be at the convergence of AI-powered image analysis and precision medicine. Our guests are Jonathan Daniels and Ori Zelikov, MD from Nucleai, who are committed to bringing the power of spatial biology to reality by providing pharmaceutical companies and clinicians with AI- powered image analysis applications. We're going to be talking ...
Oct 28, 2021•32 min
The technology in digital pathology has been with us for some time. It now, though, seems we've hit an inflection point and things are accelerating. Perhaps we are even in the perfect storm. There seems to be a certain sense of inevitability and it may be time to open the floodgates and release the promise of digital pathology. Our guests are Colin White - Senior Vice President and General Manager, Advanced Staining & Imaging at Leica Biosystems and Frank Gannon, Professor of Pathology at Baylor...
Oct 21, 2021•40 min
Our guest is Esther Abels, Chief Clinical Officer and Chief Regulatory Officer at Visiopharm, as well as the president-elect of the Digital Pathology Association. Esther also leads the regulatory and standards task force at the DPA with a focus on FDA collaborations to drive regulatory and standard classifications for interoperability and computational pathology in the field of digital pathology. We're going to be talking about standardization in digital pathology - not only in preanalytical fac...
Oct 14, 2021•36 min
Is your lab or institution ready for a disaster? Dr. Elizabeth Neyens has over 15 years of experience in translational drug development and has held various staff pathology positions in contract research organizations, the pharmaceutical industry and as well as research institutes worldwide. Dr. Neyens currently supports academia, biotechnology and pharmaceutical companies with a variety of nonclinical services at Flanders ToxPath Consulting. She is an active scientist on social media and keeps ...
Oct 07, 2021•34 min
With digital pathology, we are utilizing new methods to view images acquired from a very old technology - Hematoxylin and Eosin stained sections from formalin fixed paraffin embedded tissue, which have been prepared the same way for over 100 years. This method actually adds steps, time and expense. But what if we could also reinvent the way we handle tissue to instantaneously view images from samples without having to process to fix and process them in the traditional way? Can we move beyond par...
Sep 30, 2021•30 min
Our Guest is John Waller, PhD, Chief Operations Officer & Founder of Oracle Bio. John has over of 15 years as a biology project leader in the pharmaceutical industry, for companies including AstraZeneca and Merck & Co. He has expertise in the integration of translational biomarkers into drug discovery programs and considerable experience in developing in vitro, ex vivo and in vivo models involving image analysis across numerous therapeutic areas. OracleBio is a global leader in quantitative digi...
Sep 24, 2021•33 min
One of the missing links in this digital transformation has been robust platforms for pathologists to interact with one another to share images and cases. KIKO, which stands for “knowledge in, knowledge out” is a slide hosting and sharing platform with many uses, including education, case and other content sharing, the ability to consult with colleagues, and even storing your own cases for later retrieval. Sites like KIKO help to democratize pathology and knowledge, which has been one of the key...
Sep 17, 2021•28 min
We're talking with Leo Grady, CEO of Paige, a company developing AI-based solutions in digital pathology to optimize patient outcomes. We're going to be talking about his experiences in diagnostics, radiology, pathology, and artificial intelligence. We’ll discuss the early history of Paige, its relationship with memorial Sloan Kettering, what products Paige is developing, what the future holds, and their strategy for developing partnerships. It’s often said that radiology is at least a decade ah...
May 27, 2021•27 min
