The technology in digital pathology has been with us for some time. It now, though, seems we've hit an inflection point and things are accelerating. Perhaps we are even in the perfect storm. There seems to be a certain sense of inevitability and it may be time to open the floodgates and release the promise of digital pathology. Our guests are Colin White - Senior Vice President and General Manager, Advanced Staining & Imaging at Leica Biosystems and Frank Gannon, Professor of Pathology at Ba...
Oct 21, 2021•40 min
Our guest is Esther Abels, Chief Clinical Officer and Chief Regulatory Officer at Visiopharm, as well as the president-elect of the Digital Pathology Association. Esther also leads the regulatory and standards task force at the DPA with a focus on FDA collaborations to drive regulatory and standard classifications for interoperability and computational pathology in the field of digital pathology. We're going to be talking about standardization in digital pathology - not only in preanalytical fac...
Oct 14, 2021•36 min
Is your lab or institution ready for a disaster? Dr. Elizabeth Neyens has over 15 years of experience in translational drug development and has held various staff pathology positions in contract research organizations, the pharmaceutical industry and as well as research institutes worldwide. Dr. Neyens currently supports academia, biotechnology and pharmaceutical companies with a variety of nonclinical services at Flanders ToxPath Consulting. She is an active scientist on social media and keeps ...
Oct 07, 2021•34 min
With digital pathology, we are utilizing new methods to view images acquired from a very old technology - Hematoxylin and Eosin stained sections from formalin fixed paraffin embedded tissue, which have been prepared the same way for over 100 years. This method actually adds steps, time and expense. But what if we could also reinvent the way we handle tissue to instantaneously view images from samples without having to process to fix and process them in the traditional way? Can we move beyond par...
Sep 30, 2021•30 min
Our Guest is John Waller, PhD, Chief Operations Officer & Founder of Oracle Bio. John has over of 15 years as a biology project leader in the pharmaceutical industry, for companies including AstraZeneca and Merck & Co. He has expertise in the integration of translational biomarkers into drug discovery programs and considerable experience in developing in vitro, ex vivo and in vivo models involving image analysis across numerous therapeutic areas. OracleBio is a global leader in quantitat...
Sep 24, 2021•33 min
One of the missing links in this digital transformation has been robust platforms for pathologists to interact with one another to share images and cases. KIKO, which stands for “knowledge in, knowledge out” is a slide hosting and sharing platform with many uses, including education, case and other content sharing, the ability to consult with colleagues, and even storing your own cases for later retrieval. Sites like KIKO help to democratize pathology and knowledge, which has been one of the key...
Sep 17, 2021•28 min
We're talking with Leo Grady, CEO of Paige, a company developing AI-based solutions in digital pathology to optimize patient outcomes. We're going to be talking about his experiences in diagnostics, radiology, pathology, and artificial intelligence. We’ll discuss the early history of Paige, its relationship with memorial Sloan Kettering, what products Paige is developing, what the future holds, and their strategy for developing partnerships. It’s often said that radiology is at least a decade ah...
May 27, 2021•27 min
The College of American Pathologists (CAP), in collaboration with the ASCP and API announced the 2021 update of guidelines for Validating Whole Slide Imaging (WSI) for diagnostic Purposes. We talk with Andrew Evans, MD, PhD, Chair of The Digital and Computational Pathology Committee and Nicole Thomas, MPH, Director of the CAP Center for Evidence Based Guidelines.
May 20, 2021•38 min
Dennis Strenk is the host of the People of Pathology Podcast and Pathologists’ Assistant at the Wisconsin Diagnostic Laboratories. Dennis has created a unique podcast to get to know the people in pathology , to understand their motivations, and to hear their stories and learn from their insights. We talk with him about the origins of the People of Pathology Podcast, lessons learned and the surprises along the way. In addition, we talk about digital pathology, gross specimen handling and imaging ...
May 13, 2021•23 min
This episode we speak with Dr. Michael Johnson of Visikol. We will discuss 3D imaging in digital pathology. We will look at the current and future uses of 3D imaging. What is the current state of the art in multiplexing - particularly for clinical use. We will find out more about organoids, what they are and what role they play in research and finally, what Visikol has in store for the future.
May 06, 2021•31 min
One of the many features of digital pathology is the capacity for increased connectivity among and between pathologists and the ability to share and collaborate on images and cases. This lends itself very nicely to the use of social media. We will examine the way pathologists use YouTube, Twitter, Facebook and other platforms including pathology specific ones such as PathPresenter and KIKO. We will look at how, in the past 10 years, social media has evolved and helped shape the practice, discuss...
Apr 29, 2021•40 min
We're speaking with Felix Faber of MindPeak and Lisa-Jean Clifford of Gestalt Diagnostics. With the recently announced partnership between Gestalt, MindPeak, and Leica for the implementation of digital pathology for Bio-Reference Laboratories, we will talk about this real world use of artificial intelligence and algorithms. We discuss how this collaboration will increase workflow efficiency and accuracy for pathologists. We will examine their AI integration for remote breast cancer diagnostics a...
Apr 27, 2021•15 min
Our guest is Chaim Linhart of IBEX Medical Analytics. We will discuss the unique challenges and opportunities for unlocking the tools of digital pathology. We examine the differences between a strong AI and narrow AI and how strong AI can assist pathologists. Why is AI the "killer app" in digital pathology and how did Ibex develop Galen, one of the first AI based solutions to be deployed in actual clinical practice.
Apr 22, 2021•30 min
With so many use cases and applications in digital pathology, how do we connect the dots and make it all work? Dr. Anil Parwani is Professor of Pathology at The Ohio State University, Vice chair of Pathology and Head of Anatomic Pathology. He is the newly elected president of the Digital Pathology Association (DPA). We will talk about some of the ways to increase adoption and possible use cases for digital pathology. We will examine how algorithms and AI tools might help and what will be the rol...
Apr 15, 2021•27 min
We are talking with Patrick Myles, the CEO of Huron Digital Pathology. In this episode, we will discuss searching images within digital pathology. We will talk about slide indexing in handling large image databases and how these new searches will open the door to democratizing digital pathology. We will examine image search for new drug discovery, clinical use, and research applications. We will also look at the new project to digitize the Joint Pathology Center's archive of glass slides.
Apr 08, 2021•23 min
Tom Barr is an industry veteran. He was an early adopter of digital pathology - utilizing various hardware platforms as well as commercial and custom software. We will look at some of the early challenges to whole slide imaging (WSI), software solutions, networking, storage and interoperability Tom was instrumental in developing VIPER (Virtual Imaging for Pathology Education and Research) at Nationwide Children's Hospital and developing the digital pathology network used in clinical trials for m...
Apr 01, 2021•28 min
We are talking with David West, CEO of Proscia and Joseph Mossel, CEO of IBEX Medical Analytics. Recently, Proscia, a leading provider of digital and computational pathology solutions, and IBEX Medical Analytics, a pioneer in artificial intelligence (AI)-based cancer diagnostics, announced a strategic partnership to support pathologists in detecting prostate cancer. In this episode, we will learn about the history of these two companies, examine how this partnership will work to help pathologist...
Mar 26, 2021•21 min
Our guest is Professor Hamid Tizhoosh, the director of the KIMIA Lab (Laboratory for Knowledge Inference in Medical Image Analysis) at the University of Waterloo. We've all heard the hype about Artificial Intelligence (AI), but what exactly is AI? In this episode, we will examine some examples of AI in everyday life. We will discuss the current and future applications of artificial intelligence in digital pathology and image analysis, the "ethics" of artificial intelligence, and why the patholog...
Mar 18, 2021•36 min
Our guest is Ahmed Hosny, a machine learning research scientist, author and blogger from the Dana Farber Cancer Institute, who has a developed a framework for evaluating AI startups. This episode, we are talking about artificial intelligence (AI), machine learning (ML), and deep learning. We will touch on the history of AI and how it has been used to train neural networks. Pathology seems to be behind radiology with the number AI start-ups. We will find out some of the reasons why. We will discu...
Mar 11, 2021•29 min
Our guest is Dr. Steven Hinrichs, Professor and Chair in the Department of Pathology and Microbiology at the University of Nebraska. This episode, we focus on creating an effective team to transition to digital pathology. We will learn what types of teams are needed and the challenges in building those groups. We also look at the psychology of pathology. We will examine how the brain processes black & white images and how that impacts the new era of machine learning.
Mar 03, 2021•29 min
Our guest is Sam Terese, president and CEO of Alverno Laboratories, an integrated laboratory delivery network serving multiple healthcare systems and hospitals in the Chicagoland and Indiana area. Sam Terese has more than 30 years of experience in the laboratory environment, including settings as varied as community hospitals, academic medical centers, as well as research based organizations. Alverno, under Sam's leadership, has pursued a strategy of growth and consolidation and offers laborator...
Feb 25, 2021•36 min
Our guest is Mariano de Socarraz, president of CorePlus Servicos Clinicos y Patologicos. With over 25 years experience in anatomic pathology, CorePlus is an international specialty laboratory serving clients in the US and the Caribbean. This episode, we are talking about the digital journey that CorePlus underwent. We will discover what were the steps involved, once the decision was made to go digital, what lessons were learned and of course, what is the business case for going digital. The big ...
Feb 18, 2021•42 min
Our guest is Dr. Cory Roberts, CEO, Chairman and President of ProPath. He is a pathologist with over 20 years of experience in healthcare ranging from academic medicine to specialty private practice and currently leading ProPath, the largest 100% physician owned pathology and laboratory medicine diagnostic practice in the country. This episode, we are talking about what it takes to go digital in a large group practice. In 2020, ProPath made the leap into digital pathology. We will discover what ...
Feb 11, 2021•36 min
Our guest is Dr. Marilyn Bui from Moffitt Cancer Center a pathologist with expertise in sarcoma, pathology, cytopathology, breast cancer biomarker testing as well as digital pathology. In this episode, we are going to talk about the holistic approach to digital pathology. We will find out if digital pathology is more than the sum of its parts. We will discuss the benefits derived from being highly connected with our systems, our networks or devices, our colleagues and even ultimately, the custom...
Feb 04, 2021•40 min
Roberto Salgado, MD, PhD is a pathologist based in Belgium with expertise in breast pathology and immuno-oncology. He is Co-chair of the International Immuno-Oncology Biomarker Working Group. Over the past several years we have seen large advances and dedication of resources to immuno-oncology. We’ve also seen that information extracted by quantifying Tumor Infiltrating Lymphocytes (TILs) on routine histologic sections adds significant predictive and prognostic information in this area. We have ...
Jan 28, 2021•26 min
The global COVID-19 public health emergency brought about many changes including a relaxation of FDA regulation of slide scanners and displays in digital pathology. A notice was recently placed in the Federal Register by the FDA through Health and Human services soliciting a 90-day comment period to discuss permanently waving FDA regulation over certain medical devices. We will be discussing the significance of these possible changes with Richard Morroney, Director of Regulatory Compliance at In...
Jan 26, 2021•13 min
Dr. Singh is a Professor in Dermatology and Pathology at Northwell Health, New York. He directs the Dermatopathology Section and is the Associate Chair of Digital Pathology. He is board certified in pathology and dermatopathology and board eligible for Clinical Informatics. He is the Founder of PathPresenter, an online digital platform that has 125,000+ users in 170+ countries and is used by multiple academic departments, private pathology groups and organizations in the US and all over the worl...
Jan 21, 2021•40 min
We're talking with Dr. Markus Herrmann, Assistant Professor of Pathology at Harvard Medical School, and director of computational pathology at Mass General Hospital. At the heart of digital pathology is the transformation of images into data. And in so doing, we've unlocked the exciting field of computational pathology.
Jan 14, 2021•40 min
As we move toward full scale adoption of digital pathology, it has been said that the computer monitor is going to replace the microscope. If true, that could make the display or monitor one of the most important pieces of equipment. This episode of Digital Pathology Today™ we will focus on monitors and displays, the different levels and grades (consumer vs. medical), how displays are evaluated, the pixel pathway, and the FDA role. We are talking with Jacob Abel of University of Michigan whose p...
Jan 07, 2021•36 min
This special year end addition will feature a look back add some of the hot topics and memorable guests we've had on the podcast. We'll go way back - over 100 years - to the foundations of pathology and look at what pathology as a discipline has done very well and what the future will hold. We'll look at comparisons of pathology to radiology in terms of barriers to adoption and timelines in converting to digital systems. 2020 was a memorable year, and the most striking event or series of events ...
Dec 31, 2020•38 min
