In this rapid webinar, Meredith E. Clement, MD, and Linda-Gail Bekker, MBChB, DTMH, DCH, FCP(SA), PhD, provide an overview of important topics and studies presented at HIVR4P 2024, including: Expanding PrEP options based on results from PURPOSE 2, IMPOWER-22, IMPOWER-24, IPM 054, MTN-025/HOPE OLE, CATALYST, and the HPTN 084 substudy Implementing injectable PrEP based on results from PEPFAR, the USAID DISCOVER-Health LA CAB Demonstration Project in Zambia, and the LA CAB PrEP Rapid Start Model in...
Oct 30, 2024•46 min•Ep. 415
Listen in as Rebekah Fenton, MD, MPH, and Sharon G. Humiston, MD, MPH, discuss strategies to achieve health equity in HPV vaccination, including: Trends among males vs females Messaging considerations for those from diverse populations (eg, LGTBQ+ and rural communities) How healthcare professionals can address barriers to care Then, hear answers from the experts to frequently asked questions regarding HPV vaccination recommendations, timing, and example case studies. Presenters : Rebekah Fenton,...
Oct 29, 2024•26 min•Ep. 416
In this rapid webinar, Meredith E. Clement, MD, and Linda-Gail Bekker, MBChB, DTMH, DCH, FCP(SA), PhD, provide an overview of important topics and studies presented at HIVR4P 2024, including: Expanding PrEP options based on results from PURPOSE 2, IMPOWER-22, IMPOWER-24, IPM 054, MTN-025/HOPE OLE, CATALYST, and the HPTN 084 substudy Implementing injectable PrEP based on results from PEPFAR, the USAID DISCOVER-Health LA CAB Demonstration Project in Zambia, and the LA CAB PrEP Rapid Start Model in...
Oct 28, 2024•46 min•Ep. 414
Listen in as Rebekah Fenton, MD, MPH, and Sharon G. Humiston, MD, MPH, discuss strategies to improve your messaging techniques with the HPV vaccine, including: Persisting in vaccine recommendation after initial refusal Educating patients and their families together Ensuring staff are trained to correctly answer questions Knowing when interested patients in your state can consent to vaccination without needing parental consent Presenters : Rebekah Fenton, MD, MPH Adolescent Medicine Physician Ali...
Oct 28, 2024•14 min•Ep. 413
Listen in as Sharon G. Humiston, MD, MPH, discusses current trends in HPV, including: Incidence and prevalence trends in the US Sex-related features of HPV-attributable cancers How HPV vaccination uptake can prevent certain types of cancer Current guidelines and recommendations for HPV vaccination Presenter : Sharon G. Humiston, MD, MPH Director for Research Associate Editor of IZ-Express Immunize.org Rochester, New York To access all of our new podcast episodes, subscribe to the CCO Infectious ...
Oct 28, 2024•17 min•Ep. 412
In this episode, Kathleen Page, MD, and Glenn J. Treisman, MD, PhD, discuss the interplay between addiction and HIV. Learn as they share their approaches to reframing the conversation about addiction and overcoming barriers to effective addiction care for people living with HIV. Presenters: Kathleen Page, MD Professor Infectious Diseases Johns Hopkins School of Medicine Baltimore, Maryland Glenn J. Treisman, MD, PhD Eugene Meyer III Professor of Psychiatry and Medicine Johns Hopkins University S...
Oct 08, 2024•31 min•Ep. 411
In this episode, Alexander Wong, MD, FRCPC, discusses how to optimize treatment and engagement in care for individuals with HIV and substance use disorder, including: Barriers to care for persons with substance use disorder Colocating HIV and other services (eg, addiction care medicine, social services) Leveraging a multidisciplinary approach to care Integrating a low-barrier model to foster an environment of open discussion Best practices for opioid agonist therapy implementation Considerations...
Sep 13, 2024•16 min•Ep. 410
In this episode, Jennifer Cocohoba, PharmD, AAHIVP, and David Koren, PharmD, MPH, AAHIVP, FIDSA, cover the most impactful LA ART and LA PrEP clinical studies presented at AIDS 2024, including: The PURPOSE 1 study of twice-yearly lenacapavir injections vs daily oral tenofovir as PrEP in cisgender women An open-label extension of HPTN 084 evaluating LA CAB safety during pregnancy 48-week data from the IMPAACT 2017/MOCHA study of LA CAB + RPV in adolescents with HIV A substudy of FLAIR evaluating t...
Aug 30, 2024•18 min•Ep. 409
In this episode, Tristan J. Barber, MA, MD, FRCP, and Glenn J. Treisman, MD, PhD, discuss the importance of screening, diagnosing, and treating PTSD in people with HIV. They illustrate their discussion through a patient case and provide strategies for accomplishing this, sharing their own experiences and approaches to thinking about PTSD, structuring appointments, and integrating care. Presenters: Tristan J. Barber, MA, MD, FRCP Consultant in HIV Medicine Royal Free London NHS Foundation Trust H...
Aug 27, 2024•38 min•Ep. 408
In this episode, Colleen F. Kelley, MD, MPH, and Jemma Samitpol discuss key considerations to improve the patient experience among transgender persons with HIV, including: Unique circumstances faced by transgender people trying to access HIV care (eg, stigma, discrimination) Best practices to improve access and linkage to HIV care Ways to integrate gender-affirming care into HIV care Creating a welcoming and inclusive environment Offering same-day HIV treatment Addressing potential drug–drug int...
Aug 22, 2024•37 min•Ep. 407
In this episode featuring faculty from the United States and Europe, Aadia I. Rana, MD, and Laurence Slama, MD, PhD, discuss the subtleties of deciding among HIV treatment options in people with adherence challenges. Listen as they debate the potential risks and benefits of long-acting ART in this population, considerations for people with viremia or resistance, recommendations concerning proviral DNA genotyping, and how to interpret guidelines and provide truly patient-centered care. Presenters...
Aug 22, 2024•41 min•Ep. 406
In this episode, Gregory Huhn, MD, MPHTM, presents a case study of a person with a long HIV treatment history, exploring when and how to consider agents with novel mechanisms of action. Listen as he discusses: The importance of engaging with patients to understand their perspectives and improve their satisfaction with their HIV care Options in people with multiclass resistance Studies of agents with novel mechanisms of action: BRIGHTE (fostemsavir) TMB-301/-311 (ibalizumab) CAPELLA (lenacapavir)...
Aug 16, 2024•13 min•Ep. 405
In this episode, Yvonne Gilleece, MB BCh, BAO, FRCP, uses a case study to illustrate why giving people space and time to engage in HIV care on their terms is key to overcoming potential shame and stigma. She discusses how people can be very vulnerable when engaging in HIV care, and trauma-informed care can help address these vulnerabilities in a safe, respectful way. Listen as she gives her perspectives on: Trauma-informed care Overcoming stigma and shame Staying in care Presenter: Yvonne Gillee...
Aug 16, 2024•6 min•Ep. 404
In this episode, George Lau, MD, FRCP (Edin, Lond), FHKAM (Med), FHKCP, FAASLD, MBBS (HKU), and a patient discuss opportunities to optimize care for people living with hepatitis B virus (HBV), including: Consequences to poor adherence to antiviral therapy Strategies to promote medication adherence (eg, patient education, setting up routines) The role of routine monitoring to prevent complications related to HBV such as hepatocellular carcinoma Presenter: George Lau, MD, FRCP (Edin, Lond), FHKAM ...
Aug 15, 2024•12 min•Ep. 403
In this episode, Gregory Huhn, MD, presents a case study exploring how to optimize oral ART for a person with a long history of different ART regimens. Listen as he discusses: Reasons to consider regimen optimization in the setting of viral suppression Evidence for INSTIs in the setting of resistance Data on when 2-drug regimens and long-acting regimens may or may not be good options Faculty Gregory Huhn, MD Interim Chief, Division of Infectious Diseases Senior Director of HIV Services Cook Cou...
Aug 14, 2024•10 min•Ep. 402
In this episode, Lucas Hill, PharmD, AAHIVP, BCACP, and Bernadette Jakeman, PharmD, PhC, BCPS, AAHIVP,discuss what pharmacists need to know to provide high-quality HIV care beyond viral suppression, including treatment strategies and tips for addressing and improving patients’ quality of life. Listen as they discuss: Reasons to consider regimen optimization in the setting of viral suppression Evidence that LA ART may reduce internalized stigma DHHS recommendations on proviral DNA genotyping Fa...
Aug 09, 2024•13 min•Ep. 401
In this episode, Stuart C. Gordon, MD, FACP, FACG, AGAF, FAASLD; Marlyn J. Mayo, MD; and Brenda Remo discuss strategies for optimizing PBC pruritus care in the clinic setting. Listen to their conversation on how important it is to ask patients about their pruritus, validate their symptoms and feelings, and offer treatment options framed with realistic expectations. Presenters: Stuart C. Gordon, MD, FACP, FACG, AGAF, FAASLD Professor of Medicine Wayne State University School of Medicine Director,...
Jul 29, 2024•21 min•Ep. 400
In this episode, Stuart C. Gordon, MD, FACP, FACG, AGAF, FAASLD; Marlyn J. Mayo, MD; and Brenda Remo discuss the patient experience with cholestatic pruritus in PBC. Listen to their conversation on how people describe the experience of cholestatic pruritus, the extent to which pruritus negatively affects quality of life, and the importance of educating healthcare professionals on this important symptom of PBC. Presenters: Stuart C. Gordon, MD, FACP, FACG, AGAF, FAASLD Professor of Medicine Wayne...
Jul 29, 2024•13 min•Ep. 399
In this episode, Bradley N. Gaynes, MD, MPH, and Glenn J. Treisman, MD, PhD, discuss the importance of screening, diagnosing, and treating depression in people living with HIV. They illustrate their discussion through a patient case and provide strategies for accomplishing this, including creation of a virtual network and employment of measurement-based care. Presenters: Bradley N. Gaynes, MD, MPH Ray M. Hayworth, MD and Family Distinguished Professor Professor of Psychiatry and Epidemiology Dir...
Jul 24, 2024•51 min•Ep. 398
In this episode, Cristina Mussini, MD,and William R. Short, MD, MPH, FIDSA,discuss the potential role of ART in weight change among people living with HIV. Listen to their conversation on whether ART switch can lead to weight loss after weight gain and how to counsel people living with HIV on weight loss options, including lifestyle modifications and nonpharmacologic methods. Presenters Cristina Mussini, MD Director of Infectious Diseases Clinics Professor of Infectious Diseases University o...
Jun 27, 2024•24 min•Ep. 397
In this episode, Linda-Gail Bekker, MBChB, DTM&H, DCH, FCP(SA), PhD, uses a case study to illustrate why patients living with HIV may disengage with their care and how best to reengage them once they present at the clinic, including discussion of: The valid reasons patients have for disengaging with their HIV care Why the return to care should be celebrated How to support people living with HIV as they reengage in care How to prevent future loss to follow-up Presenter: Linda-Gail Bekker, MBC...
Jun 17, 2024•13 min•Ep. 396
In this second podcast of our series, hear expert faculty explore the CDC recommendations for mpox protection and discuss how vaccination can lead to immunologic equity. Topics include: Should we consider mpox an STI? What strategies can be used to improve mpox vaccination and overcome the challenges of vaccine implementation? Can mpox vaccine be coadministered with other vaccines? What is the intersection between mpox and HIV? Presenters Carlos del Rio, MD Distinguished Professor of Medicine (I...
Jun 14, 2024•14 min•Ep. 395
Hear expert faculty answer common questions about the risk, impact, and recommendations for protection against mpox, including: Why is mpox relevant to clinical practice? Who is at highest risk for mpox? How is mpox transmitted, and what are the clinical manifestations and complications of mpox infections? What are current ACIP recommendations for mpox vaccination? What about pre- and postexposure vaccination? Presenters Carlos del Rio, MD Distinguished Professor of Medicine (Infectious Diseases...
Jun 14, 2024•20 min•Ep. 394
In this episode, Roger Bedimo, MD, MS, FACP, examines patient and regimen-based PrEP barriers and discusses practical interventions to support PrEP adherence in key populations. Topics covered include: Individual and community perspectives on PrEP barriers Key barriers by principal populations Strategies to support PrEP delivery PrEP options for key populations PrEP efficacy based on adherence in cisgender men and women Comparing FTC/TDF vs FTC/TAF or CAB for PrEP PrEP in pregnancy and breastfee...
May 31, 2024•12 min•Ep. 393
In this episode, Roger Bedimo, MD, MS, FACP, discusses strategies to overcome health disparities to improve PrEP uptake, including: Targeting key populations that would benefit from PrEP but have low rates of uptake, such as transgender women and people who inject drugs Addressing intersectionality Overcoming implicit bias Addressing PrEP inequity by geographic region Expanding PrEP uptake by expanding HCPs who prescribe it Improving PrEP education for both patients and HCPs Presenter : Roger Be...
May 31, 2024•15 min•Ep. 392
In this episode, Roger Bedimo, MD, MS, FACP, examines provider-based and structural PrEP barriers and discusses practical methods for healthcare professionals to overcome these challenges. Topics covered include: Potential provider barriers to prescribing PrEP Strategies to facilitate conversations about PrEP Addressing the gap in PrEP provider training Structural barriers for PrEP coverage, such as lack of insurance and complexity of billing Informed consent for minors CDC guidelines on HIV tes...
May 31, 2024•15 min•Ep. 391
In this episode, Tristan J. Barber, MA, MD, FRCP, and Roger Bedimo, MD, MS, FACP, help you decide whether and how to modify ART in virologically suppressed individuals by critically appraising whether using newer agents may improve their treatment satisfaction. Listen to their conversation about their own approaches to evaluating whether each person living with HIV is taking the best ART regimen for them, as well as ways to proactively assess challenges people may be facing with their HIV ART. P...
May 16, 2024•21 min•Ep. 390
In this episode, Jonathan Appelbaum, MD, FACP, AAHIVS, discusses the updated CDC guidance on how to monitor for HIV in people receiving PrEP, including: Rationale for why HIV monitoring differs for people receiving LA vs daily PrEP Description of LEVI syndrome How to transition a person from LA PrEP to HIV ART if they test positive for HIV Presenter: Jonathan Appelbaum, MD, FACP, AAHIVS Laurie L. Dozier, Jr., MD Education Director and Professor of Internal Medicine Chair, Department of Clinical ...
May 10, 2024•6 min•Ep. 389
In this episode, Jonathan Appelbaum, MD, FACP, AAHIVS, discusses the newest data supporting LA ART use in people with adherence challenges or viremia, including: The LATITUDE study, an open-label phase III study of LA CAB + RPV in people with a suboptimal response or nonadherence to oral ART Updates to the Ward 86 cohort, which showed 81% of patients with viral suppression on LA CAB + RPV at Week 48 The CARES study, an open-label, noninferiority phase IIIb study of LA CAB + RPV in people with ba...
May 10, 2024•10 min•Ep. 388
In this episode, Angela Branche, MD, FIDSA, and Jewel Mullen, MD, MPH, MPA, FACP, address commonly asked questions about the RSV vaccine, including: Considerations for vaccine eligibility Recommendations for pregnant persons Vaccine administration based on RSV seasonality Use of the vaccine in persons receiving immunosuppressive medications Safety data (eg, risk of serious adverse events) Natural immunity of RSV Vaccine cost and insurance coverage Faculty: Angela Branche, MD, FIDSA Associate Pro...
May 08, 2024•9 min•Ep. 387
