Deep Tech Renaissance: John Lee on Emerging Technologies and Capital Allocation - podcast episode cover

Deep Tech Renaissance: John Lee on Emerging Technologies and Capital Allocation

Oct 23, 202350 minSeason 14Ep. 18
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Episode description

Introduction:
  • John Lee is an early-stage investor focusing on deep tech, enterprise software, cybersecurity, AI/ML, and automation.
What is Deep Tech?
  • Deep tech companies are similar to biotech companies in terms of capital structure.
  • Unlike traditional tech startups, they have a longer incubation period to accrue value.
Capital Allocation and Business Models
  • Scarcity of capital drives better business models.
  • Interesting hybrid models exist that are designed to develop revenue in the near term.
Examples from the Portfolio
  • Rare Base: Focuses on finding cures for rare diseases by characterizing cells and testing drugs on them. Sells IP assets as a novel business idea.
  • Count: Aims to make accounting firms more efficient by acquiring existing firms and implementing AI techniques.
Innovation in Deep Tech
  • Despite a renaissance in funding, deep tech has not yet penetrated the lives of ordinary consumers.
  • The scarcity of capital is forcing companies to be more creative in their go-to-market strategies.
Notable Geographical Clusters
  • San Francisco and Boston are significant clusters for deep tech companies.
Artificial Intelligence and Large Language Models (LLMs)
  • LLMs are seen as collections of human intelligence trained on internet content.
  • Emergent properties arise from the crosstalk across different nodes in LLMs.
Future of LLMs
  • Doubts exist about the ability of current models to scale.
  • OpenAI aims to develop models with 100 trillion parameters, although the feasibility of this is debated.
The Intersection of Science and Deep Tech
  • Science is transitioning from an "artisanal" practice to an engineering discipline.
Application Areas
  • Reproductive Innovations: Research is being conducted on how to effectively assist couples in having children later in life.
  • Energy: A debate exists over the effectiveness of fusion vs fission in energy production.
Business Model Concerns
  • Long regulatory approval times are a challenge.
  • Jazz Venture Partners focuses on the convergence of deep tech and science, aiming for creative translation.
Deep Tech Renaissance: John Lee on Emerging Technologies and Capital Allocation | Crazy Wisdom podcast - Listen or read transcript on Metacast