This week, please join author Bruce Wasserman and Associate Editor Mercedes Carnethon as they discuss the article "Intracranial Atherosclerotic Disease and Incident Dementia: the Atherosclerosis Risk in Communities Study (ARIC)." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20240906.944975...
This week, please join author Gregory Wyant and Associate Editor Gabriele Schiattarella as they discuss the article "Induction of DEPP1 by HIF Mediates Multiple Hallmarks of Ischemic Cardiomyopathy." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20240830.316198...
This week, please join author Gary Owens and Associate Editor Iris Jaffe as they discuss the article "A Novel Mouse Model of Myocardial Infarction, Plaque Rupture, and Stroke Shows Improved Survival With Myeloperoxidase Inhibition." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20240825.966308...
This week, please join author Marius Hoeper and Associate Editor Kelly Chin as they discuss the article "Tadalafil for Treatment of Combined Postcapillary and Precapillary Pulmonary Hypertension in Patients With Heart Failure and Preserved Ejection Fraction: A Randomized, Controlled Phase 3 Study." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20240816.125469...
This week, please join author Rachel Lampert as she discusses the article "Vigorous Exercise in Patients with the Congenital Long-QT Syndrome: Results of the Prospective, Observational, Multinational, LIVE-LQTS Study." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20240809.114150...
This week, please join author Hiroyuki Daida and Associate Editor Amit Khera as they discuss the article "A Randomized Trial for Evaluation in Secondary Prevention Efficacy of Combination Therapy−Statin and Eicosapentaenoic Acid (RESPECT-EPA)." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20240804.906883...
This week, please join author Rod Passman and Associate Editor Mark Link as they discuss the article "Association of Atrial Fibrillation Burden and Mortality Among Patients With Cardiac Implantable Electronic Devices." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20240729.689092...
This week, please join author John J.V. McMurray and Guest Editor Frank Ruschitzka as they discuss the article "Effect of Sacubitril/Valsartan on Cognitive Function in Patients With HFpEF: A Prespecified Analysis of PARAGON-HF." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20240719.555489...
This week, Circulation is proud to present the 4th annual Disparities issue. First, Guest Editor Latha Palaniappan leads the interview with author Jennifer Green as they discuss the article "Effects of an Intervention to Improve Evidence-Based Care for People With Diabetes and Cardiovascular Disease Across Sex, Race, and Ethnicity Subgroups: Insights From the COORDINATE-Diabetes Trial." Then, Disparities Editor Mercedes Carnethon talks with author Benjamin Zielonka about his article "Childhood O...
This week, please join first author Heerajnarain Bulluck as he discusses the article "Effect of Cangrelor on Infarct Size in ST-Segment−Elevation Myocardial Infarction Treated By Primary Percutaneous Coronary Intervention: A Randomized Controlled Trial (The PITRI Trial)." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20240703.90241...
This week, please join authors Reza Nezafat, Shiro Nakamori, and Amine Amyar as they discuss the article "Cardiovascular Magnetic Resonance Radiomics to Identify Components of the Extracellular Matrix in Dilated Cardiomyopathy." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20240628.66549...
This week, please join Social Media Editors Shirin Doroudgar and Susmita Sahoo as they speak with the 2024 Loscalzo Award recipient, Mark C. Blaser, regarding his article "Multiomics of Tissue Extracellular Vesicles Identifies Unique Modulators of Atherosclerosis and Calcific Aortic Valve Stenosis." The Loscalzo Award recognizes the best Basic/Translational article published in Circulation in the preceding 12 months. For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podca...
This week, please join author Laura Galian-Gay and Associate Editor Joshua Beckman as they discuss the article "Atorvastatin Effect on Aortic Dilatation and Valvular Calcification Progression in Bicuspid Aortic Valve (BICATOR): A Randomized Clinical Trial." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20240614.566029...
This week, please join author David Kandzari and Associate Editor Wanpen Vongpatanasin as they discuss the article "Effect of Alcohol-Mediated Renal Denervation on Blood Pressure in the Presence of Antihypertensive Medications: Primary Results From the TARGET BP I Randomized Clinical Trial." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20240607.177703...
This week, please join author Siddharth Patel and Guest Editor Ileana Piña as they discuss the article "Sodium-Glucose Cotransporter 2 Inhibitors and Major Adverse Cardiovascular Outcomes: A SMART-C Collaborative Meta-Analysis." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20240531.705195...
This week, please join authors Jonathan Leor and Tal Caller, as well as Associate Editor Gabriele Schiattarella as they discuss the article "Small Extracellular Vesicles From Infarcted and Failing Heart Accelerate Tumor Growth." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20240524.921966...
This week, please join author Adrian Hernandez as he discusses the article "Effect of Empagliflozin on Heart Failure Outcomes After Acute Myocardial Infarction: Insights From the EMPACT-MI Trial." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20240515.717282...
This week, please join author Stephan Rosenkranz, Editorialist Lewis Rubin, and Associate Editor Kelly Chin as they discuss the article "Positive Vasoreactivity Testing in Pulmonary Arterial Hypertension: Therapeutic Consequences, Treatment Patterns, and Outcomes in the Modern Management Era" and the Editorial "Is There a Role for Calcium Channel Blockers in the Contemporary Treatment Paradigm for Pulmonary Arterial Hypertension?" For the episode transcript, visit: https://www.ahajournals.org/do...
This week, please join author Kristoffer Berg-Hansen and Section Editor and Editorialist Stayam "Tom" Sarma as they discuss the article "Cardiovascular Effects of Oral Ketone Ester Treatment in Patients With Heart Failure With Reduced Ejection Fraction: A Randomized, Controlled, Double-Blind Trial." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20240503.968091...
This week, please join author Amy Lin and Statistical Editor Dan (Amanda) Tong as they discuss the article "Clonal Hematopoiesis of Indeterminate Potential With Loss of Tet2 Enhances Risk for Atrial Fibrillation Through Nlrp3 Inflammasome Activation." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20240426.766271...
This week, please join author Prakriti Gaba as she discusses the article "Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting in Patients With Left Main Disease With and Without Diabetes: Findings From a Pooled Analysis of 4 Randomized Clinical Trials." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20240422.957293...
This week, please join author Gilles Montalescot as he discusses the article "Postprocedural Anticoagulation After Primary Percutaneous Coronary Intervention for ST-Segment−Elevation Myocardial Infarction: A Multicenter, Randomized, Double-Blind Trial." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20240412.432949...
This week, please join author Hanjoong Jo, editorialist M. Luisa Iruela-Arispe, and Associate Editor Charles Lowenstein as they discuss the article "HEG1 Protects Against Atherosclerosis by Regulating Stable Flow-Induced KLF2/4 Expression in Endothelial Cells," as well as the Editorial "Hemodynamic Forces and Atherosclerosis: HEG1 at the Center of the Jigsaw Puzzle." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20240408.470208...
This week, please join author Nicholas Mills as he discusses the article "Machine Learning for Myocardial Infarction Compared With Guideline Recommended Diagnostic Pathways. For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20240329.877789...
This week, please join author William McIntyre, Editorialist Christian Ruff, and Associate Editor Shinya Goto as they discuss the article "Direct Oral Anticoagulants for Stroke Prevention in Patients With Device-Detected Atrial Fibrillation: A Study-Level Meta-Analysis of the NOAH-AFNET 6 and ARTESiA Trials." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20240322.70604...
This week, please join author John Triedman and Associate Editor Gerald Greil as they discuss the article "Pediatric ECG-Based Deep Learning to Predict Left Ventricular Dysfunction and Remodeling." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20240315.583656...
This week, please join author Kieran Docherty and Associate Editor Justin Grodin as they discuss the article "Effect of Dapagliflozin Versus Placebo on Symptoms and 6-Minute Walk Distance in Patients With Heart Failure: The DETERMINE Randomized Clinical Trials." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20240306.916294...
This week, please join author Samir Kapadia and Editorialist Neil Kleiman as they discuss the article "Concomitant Left Atrial Appendage Occlusion and Transcatheter Aortic Valve Replacement Among Patients With Atrial Fibrillation." For the episode transcript: https://www.ahajournals.org/do/10.1161/podcast.20240301.133854...
This week, please join author Josep Rodés-Cabau and Associate Editor Dharam Kumbhani as they discuss the article "Transcatheter or Surgical Aortic Valve Replacement in Patients With Severe Aortic Stenosis and Small Aortic Annulus: A Randomized Clinical Trial." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20240226.780348...
This week's podcast features a panel discussion. Please join authors Masahiro Natsuaki, Myeong-Ki Hong, and Robert Storey, as well as Associate Editor Stefan James as they discuss the Original Research Articles "An Aspirin-Free Versus Dual Antiplatelet Strategy for Coronary Stenting: STOPDAPT-3 Randomized Trial" and "Stopping Aspirin Within 1 Month After Stenting for Ticagrelor Monotherapy in Acute Coronary Syndrome: The T-PASS Randomized Noninferiority Trial" and the Editorial "Antiplatelet The...
