Large language models (LLMs) have now achieved many of the longstanding goals of the quest for generalist AI. While LLMs are still very imperfect (though rapidly improving) in areas like factual grounding, planning, reasoning, safety, memory, and consistency, they do understand concepts, are capable of insight and originality, can problem-solve, and exhibit many faculties we have historically defended vigorously as exceptionally human, such as humor, creativity, and theory of mind. At this point...
Apr 08, 2023•23 min
Evolution always presented life forms with new challenges -- due to changes in weather, terrain, competition between different organisms, and other reasons. To increase the chance of survival, instead of solely optimizing current performance, it is in an agent's interest to maximize its ability to adapt to changes. Possibly this old evolutionary trait manifests itself in modern humans in their ability to adapt to new tasks and challenges quickly. Even if we consider a lifetime of a human, the ab...
Mar 31, 2023•24 min
Feedback interconnections are widespread in the brain; yet clear explanations for most of them are currently lacking. Carmen Amo Alonso and John Doyle explore current experimental evidence on the relationship between the auditory and motor parts of the brain during speech perception and production. These models provide a plausible explanation for how the structure of language, as described in the Parallel Architecture, is implemented in the brain. Together, they provide a plausible account for h...
Mar 28, 2023•21 min
Anthropogeny, has provided many new discoveries over the past decade, ranging from new fossil finds to ancient DNA data, including from extinct hominins. New methods and multi-disciplinary collaborations are providing exciting new insights into the complicated evolutionary journey that gave rise to our species. However, we remain far from understanding some of the most striking human-specific characteristics: the reasons for our bipedality, the factors selecting for our dexterity at creating and...
Mar 05, 2023•1 hr
Anthropogeny, has provided many new discoveries over the past decade, ranging from new fossil finds to ancient DNA data, including from extinct hominins. This CARTA symposium highlights where future efforts should be focused and what type of novel collaborations are most promising to improve our understanding of the human phenomenon. Evan Eichler talks about the discovery and resolution of genetic variation which is critical to understanding disease and evolution. The data suggests that large-sc...
Feb 22, 2023•50 min
Anthropogeny, has provided many new discoveries over the past decade, ranging from new fossil finds to ancient DNA data, including from extinct hominins. This CARTA symposium highlights where the future efforts should be focused and what type of novel collaborations are most promising for improving our understanding of the human phenomenon. Pascal Gagneux offers a zoological view of the human cultural animal. Robert Kluender talks about the evolution of language structure and the future of lingu...
Feb 20, 2023•51 min
Anthropogeny, has provided many new discoveries over the past decade, ranging from new fossil finds to ancient DNA data, including from extinct hominins. This CARTA symposium highlights where the future efforts should be focused and what type of novel collaborations are most promising for improving our understanding of the human phenomenon. Yohannes Haile-Selassie discusses the importance of fossil based human origin research. Carol Marchetto talks about the use of stem cells to study human orig...
Feb 17, 2023•43 min
Anthropogeny, has provided many new discoveries over the past decade, ranging from new fossil finds to ancient DNA data, including from extinct hominins. This CARTA symposium highlights where the future efforts should be focused and what type of novel collaborations are most promising for improving our understanding of the human phenomenon. Terry Sejnowski discusses how large-scale neural network models have inspired major advances in artificial intelligence. Sarah Tishkoff talks on how Africa i...
Feb 10, 2023•48 min
Current knowledge of our deep past is primarily derived from ancient fossils of our ancestors that paleoanthropologists search for and discover in some of the most remote areas of the world. In the last two decades, significant fossil discoveries have been made and these discoveries have re-written some parts of our deep past. However, the fossil record is still far from complete, primarily due to the absence of fossils from some critical geological times and the lack of robust samples for the s...
Jan 06, 2023•21 min
Anthropogeny, has provided many new discoveries over the past decade, ranging from new fossil finds to ancient DNA data, including from extinct hominins. New methods and multi-disciplinary collaborations are providing exciting new insights into the complicated evolutionary journey that gave rise to our species. However, we remain far from understanding some of the most striking human-specific characteristics: the reasons for our bipedality, the factors selecting for our dexterity at creating and...
Jan 06, 2023•7 min
For the past 30 years, the frontiers of language science have been in the areas of neurolinguistics and genetics, both of which arose in conjunction with new technologies emerging in the 1990s. It is probably safe to say that these trends will continue apace as technology in these areas continues to advance, allowing for increasingly sophisticated and fine-grained analysis. From its inception, the study of language has been inextricably linked with cultural anthropology and the arts. It was only...
Dec 25, 2022•21 min
Human cognition and behavior are highly heritable and so is liability to disorders that affect them. This includes neuropsychiatric disorders such as schizophrenia and autism spectrum disorder (ASD). We have started to integrate genetic risk data with the emerging maps of gene regulation to study human specific aspects of gene expression and gene regulation. These analyses indicate that human specific aspects of gene regulation, such as genes regulated by human specific enhancers, are indeed enr...
Dec 24, 2022•24 min
Africa is thought to be the ancestral homeland of all modern human populations within the past 300,000 years. It is also a region of tremendous cultural, linguistic, climatic, and genetic diversity. Despite the important role that African populations have played in human history, they remain one of the most underrepresented groups in human genomics studies. A comprehensive knowledge of patterns of variation in African genomes is critical for a deeper understanding of human genomic diversity, the...
Dec 21, 2022•25 min
The first Neandertal DNA was recovered 25 years ago, and since then, ancient DNA has provided many surprising insights into human evolutionary history. Among these are the discoveries of the multiple admixture events among late Pleistocene humans and the remnants of archaic DNA in our own genomes. How does ancient DNA research contribute to the future of anthropogeny? In this talk, I will reflect on the findings of last quarter century of ancient DNA research about archaic humans and their envir...
Dec 17, 2022•15 min
Our species is between 300,000 and 200,000 years old. For most of this one-quarter of a million years, up until just 12,000 years ago, it appears that our ancestors lived in small populations, in small-scale societies of which we can only guess the real nature. We remain in the dark about the age of some of the most diagnostic features of our species: our striding bipedalism, complex tool manufacture and use, fire use, language and societies defining their own identities, collaborating with and ...
Dec 17, 2022•16 min
The discovery and resolution of genetic variation is critical to understanding disease and evolution. Our most recent work sequences diverse human and nonhuman primate genomes using both ultra-long and high-fidelity long-read sequencing technologies. Advances in this area have made possible the first telomere-to-telomere assemblies of the human genome and much more complete chimp, gorilla and orangutan genomes providing new biological insights into regions typically excluded from human genetic a...
Dec 10, 2022•26 min
Neuroscience has made great strides in the last decade following the Brain Research Through Advancing Innovative Neurotechnologies (BRAIN) Initiative, a science and engineering grand challenge that has greatly accelerated research on large-scale recordings from neurons and reconstructions of neural circuits. Large-scale neural network models have in turn inspired major advances in artificial intelligence. These network models have been trained on large-scale data sets to recognize objects in ima...
Dec 05, 2022•23 min
The human brain has a larger mass with respect to body weight, increased cortical neurons with respect to size, an expanded proliferative zone, and unique connectivity patterns. Human-specific neurodevelopment is not only marked by physical differences, but also by temporal changes. Human neurons, during both prenatal neurodevelopment and adult neurogenesis, exhibit an exceptionally delayed time course, a characteristic termed neoteny. Signatures of human-specific neoteny have been observed and ...
Nov 26, 2022•22 min
As humans have evolved, so has our ability to drastically alter the planet we call home. In this collection of talks from the CARTA symposium, "Humans: The Planet-Altering Apes" you will learn about specific examples on how humans have changed Earth and what can be done to prevent its cataclysmic demise. David Holway addresses the challenges of emerging invasive species in our ecosystem. Oliver Ryder discusses the accelerated rate of loss of species due to human activities. Patricia Hunt talks a...
Sep 24, 2022•52 min
As humans have evolved, so has our ability to drastically alter the planet we call home. In this collection of talks from the CARTA symposium, "Humans: The Planet-Altering Apes" you will learn about specific examples on how humans have changed Earth and what can be done to prevent its cataclysmic demise. Rob Knight will talk about how all microbiomes that have been studies are impacted by human activity. Alice Goramn discusses how accumulating space debris surrounding our planet that may prevent...
Sep 18, 2022•57 min
As humans have evolved, so has our ability to drastically alter the planet we call home. In this collection of talks from the CARTA symposium, "Humans: The Planet-Altering Apes" you will learn about specific examples on how humans have changed Earth and what can be done to prevent its cataclysmic demise. Walter Willett will discuss how climate change is having devastating effects that will undermine our ability to feed the world’s growing population. Jessica Thompson talks about humans transform...
Sep 09, 2022•55 min
This CARTA public symposia addresses specific examples of how humans have drastically altered the planet. Acknowledged experts discuss clearly defined global-scale negative impacts on planet earth, our life support system (other than climate change, population growth and infectious diseases, which are well-known). Each talk succinctly describes a specific impact, the role that our species has played, and concludes with ongoing or potential approaches to mitigation. In the process, we come full c...
Aug 26, 2022•1 hr 16 min
Through the Earth Microbiome Program and complementary efforts, we have sampled a broad range of microbiomes from across the planet. All microbiomes that have been studied are impacted by human activity — the effects of industrialization on the human microbiome are best characterized, but capture of animals in zoos, domestication, modification of soils through agricultural practices, and modification of freshwater and marine microbiomes have also all been well characterized. Indeed, the pervasiv...
Jul 22, 2022•24 min
In 1957, the USSR launched Sputnik 1, the first human object to leave Earth. In the 65 years since then the region of Earth orbit has become filled with satellites and space junk. The proliferation of debris has led to the prediction of Kessler Syndrome, a state where a never-ending cascade of collisions between orbital objects renders parts of space unusable for human purposes. However, there are many different ways to look at the space junk surrounding Earth. For example, it is also an archaeo...
Jul 01, 2022•20 min
We are experiencing an accelerated rate of loss of species due to human activities. This anthropogenic phenomenon extends beyond extinction. It encompasses an expanded loss of biodiversity as the genetic diversity of species diminish, reducing gene pools to “gene puddles.” We know details of species extinctions events from the fossil record, historical record, and from ancient DNA studies, and that historical processes shape extinction risk. Habitat loss and changing eco-environmental conditions...
Jun 18, 2022•18 min
Humans now annually add more biologically available nitrogen to the Earth’s land surfaces than do all natural processes. For 3 billion years, available nitrogen had been the major limiting currency for life on Earth. The recent human disruption of the global nitrogen cycle is causing major environmental harm, including water and air pollution, marine dead zones, 10% of global greenhouse gas emissions, and species extinctions. Three major ways to solve this nitrogen problem are: (1) much more eff...
Jun 11, 2022•17 min
We are losing species much more rapidly now than in the last two million years! At this pace, we may lose a large proportion of vertebrates, including mammals, birds, reptiles, amphibians, and fishes, in the next two to three decades. Modern extinctions caused by human activities are higher than the normal or natural extinction rate which tells us that we may be causing a mass extinction. In the history of life on Earth, there have been five mass extinctions – episodes where large numbers of spe...
May 28, 2022•29 min
This CARTA public symposia addresses specific examples of how humans have drastically altered the planet. Acknowledged experts will discuss clearly defined global-scale negative impacts on planet earth, our life support system (other than climate change, population growth and infectious diseases, which are well-known). Each talk succinctly describes a specific impact, the role that our species has played, and concludes with ongoing or potential approaches to mitigation. In the process, we are co...
May 23, 2022•6 min
Beginning with Homo erectus at least a million years ago, hominins have used fire to engineer the world around them. The earliest uses of fire surely included cooking, changing the energy yields of foods. Such innovations altered the course of our evolution, facilitating the evolution of species that could adapt quickly using tools and social ingenuity. Within the last 200,000 years, hominins also used fire to change the material properties of stone, pigments, sap, and wood. While these changes ...
May 23, 2022•21 min
The introduction of species into new environments has occurred throughout human history. While most introductions fail and most of those few that establish remain environmentally innocuous, a notable minority wildly proliferates in their new ranges. These invaders disrupt ecosystems and burden economies. Environmental impacts associated with invasions are hard to predict and vary in space and time but include ecosystem-level disruptions, species extinctions, and the homogenization of biodiversit...
May 23, 2022•16 min
