Welcome to CardioNerds, where we bring you in-depth discussions with leading experts, case reports, and updates on the latest advancements in the world of cardiology. Tune in to expand your knowledge, sharpen your skills, and become a true CardioNerd!
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CardioNerds ( Drs. Rick Ferraro and Georgia Vasilakis Tsatiris ) discuss ATTR cardiac amyloidosis with expert Dr. Justin Grodin. This episode is a must-listen for all who want to know how to diagnose and treat ATTR with current available therapies, as well as management of concomitant diseases through a multidisciplinary approach. We take a deep dive into the importance of genetic testing, not only for patients and families, but also for gene-specific therapies on the horizon. Dr. Grodin draws u...
CardioNerds ( Dr. Rick Ferraro and Dr. Dan Ambinder ) join Dr. Sahar Samimi and Dr. Lorraine Mascarenhas from Baylor College of Medicine , Houston, Texas, at the Houston Rodeo for some tasty Texas BBQ and a tour of the lively rodeo grounds to discuss an interesting case full of clinical pearls involving a patient with nonbacterial thrombotic endocarditis (NBTE). Expert commentary is provided by Dr. Basant Arya . Episode audio was edited by CardioNerds Intern Dr. Bhavya Shah . (Photo by Xu Jianme...
Drs. Ferraro and Nandy, with expert Dr. Venkatesh Murthy, delve into the diagnosis of ATTR cardiac amyloidosis. They highlight crucial clinical red flags like bilateral carpal tunnel and low-voltage ECG, discuss differential diagnoses for LVH, and emphasize ruling out AL amyloidosis through specific lab tests. The episode provides an in-depth comparison of non-invasive imaging modalities like CMR and nuclear scintigraphy, explains when genetic testing is vital, and clarifies the role of biopsies, all stressing the importance of early diagnosis for effective treatment.
CardioNerds ( Dr. Claire Cambron and Dr. Rawan Amir ) join Dr. Ayan Purkayastha , Dr. David Song , and Dr. Justin Wang from NewYork-Presbyterian Queens for an afternoon of hot pot in downtown Flushing. They discuss a case of congenital heart disease presenting in adulthood. Expert commentary is provided by Dr. Su Yuan , and audio editing for this episode was performed by CardioNerds Intern, Julia Marques Fernandes . A 53-year-old woman with a past medical history of hypertension visiting from Gu...
In this episode, CardioNerds Dr. Gurleen Kaur , Dr. Richard Ferraro , and Dr. Jake Roberts are joined by Cardio-Rheumatology expert, Dr. Monica Mukherjee , to discuss the role of utilizing multimodal imaging for cardiovascular disease risk stratification, monitoring, and management in patients with chronic systemic inflammation. The team delves into the contexts for utilizing advanced imaging to assess systemic inflammation with cardiac involvement, as well as the role of imaging in monitoring v...
CardioNerds discusses HFpEF in women, highlighting its complex pathophysiology driven by metabolic and inflammatory factors, alongside under-recognized risks like sleep apnea and physical inactivity. Experts emphasize proactive prevention and an evolving therapeutic landscape including SGLT2 inhibitors and GLP-1 agonists. The conversation underscores the critical need for multidisciplinary, holistic care across a woman's lifespan to improve diagnosis and management.
CardioNerds and the Cardiogenic Shock Working Group discuss the updated AMI guidelines, which upgraded transvalvular flow pumps to a Class 2A recommendation for AMI shock. Experts analyze a complex case of an older woman with inferior STEMI and cardiogenic shock, examining her management, the application of DANGER trial findings, and the critical role of LV unloading. The discussion highlights the importance of clinical acumen, robust systems of care, and multidisciplinary shock teams to improve patient outcomes and long-term well-being beyond just survival.
CardioNerds Critical Care Cardiology Council members Dr. Gurleen Kaur and Dr. Katie Vanchiere meet with Dr. Yash Patel , Dr. Akanksha , and Dr. Mohammed El Nayir from Trinity Health Ann Arbor. They discuss a case of pulmonary air embolism, RV failure, and cardiac arrest secondary to an ocular venous air embolism. Expert insights provided by Dr. Tanmay Swadia . Audio editing by CardioNerds Academy intern, Grace Qiu . A 36-year-old man with a history of multiple ocular surgeries, including a compl...
CardioNerds ACHD Council members Dr. Rawan Amir and Dr. Claire Cambron lead a profound conversation with ACHD faculty Dr. Allison Tsao , Dr. Jill Steiner , and Dr. Katherine Salciccioli . Together, they explore the emotional and professional challenges that ACHD providers face across the lifespan of congenital heart disease. Topics discussed include navigating challenging case scenarios, empowering patients through tough decisions, leveraging multi-subspecialty expertise, celebrating the success...
CardioNerds ( Drs. Daniel Ambinder and Eunice Dugan ) are joined by Namrita Ashokprabhu , incoming medical student, along with Drs. Yulith Roca Alvarez and Mehmet Yildiz from The Christ Hospital. Expert insights provided by Dr. Odayme Quesada . Audio editing by CardioNerds intern Christiana Dangas . This episode explores how cardiac MRI and coronary function testing revealed coronary vasospasm in a case of MINOCA. Cardiac MRI is crucial in evaluating myocardial infarction with nonobstructive cor...
CardioNerds co-founders Dr. Daniel Ambinder and Dr. Amit Goyal are joined by Dr. Spencer Weintraub , Chief Resident of Internal Medicine at Northwell Health, Dr. Michael Albosta , third-year Internal Medicine resident at the University of Miami, and Anna Biggins , Registered Dietitian Nutritionist at the Georgia Heart Institute. Expert commentary is provided by Dr. Zahid Ahmad , Associate Professor in the Division of Endocrinology at the University of Texas Southwestern. Together, they discuss a...
CardioNerds ( Dr. Rick Ferraro and Dr. Dan Ambinder ) join Dr. Sri Mandava , Dr. David Meister , and Dr. Marissa Donatelle from the Columbia University Division of Cardiology at Mount Sinai Medical Center in Miami. Expert commentary is provided by Dr. Pranav Venkataraman . They discuss the following case involving a patient with cardiac sarcoidosis presenting as STEMI. A 57-year-old man with a history of hyperlipidemia presented with sudden onset chest pain. On admission, he was vitally stable w...
Dr. Daniel Judge discusses ATTR-CM, focusing on key red flags like ventricular hypertrophy and bilateral carpal tunnel syndrome, and the critical diagnostic pathway including PYP scans and genetic testing. The conversation differentiates hereditary from wild-type ATTR, exploring current treatments like TTR stabilizers and gene silencers, and delves into exciting emerging therapies such as CRISPR-Cas9 and antibody-based approaches, emphasizing the rapid advancements and the need for early diagnosis in this complex disease.
Join CardioNerds EP Council Chair Dr. Naima Maqsood and Episode Lead Dr. Jeanne De Lavallaz as they discuss the results of the VANISH2 Trial with expert faculty Dr. Jeff Healey and Dr. Roderick Tung. Audio editing by CardioNerds academy intern, Grace Qiu . The VANISH2 trial enrolled 416 patients with ischemic cardiomyopathy, an ICD in place, and recurrent episodes of sustained monomorphic ventricular tachycardia (VT) to receive either first-line VT catheter ablation or antiarrhythmic drug therap...
CardioNerds (Dr. Colin Blumenthal and Dr. Saahil Jumkhawala) join Dr. Rohan Ganti, Dr. Nikita Mishra, and Dr. Jorge Naranjo from the Rutgers – Robert Wood Johnson program for a college basketball game, as the buzz around campus is high. They discuss the following case involving a patient with ventricular tachycardia: The case involves a 61-year-old man with a medical history of hypothyroidism, hypertension, hyperlipidemia, seizure disorder on anti-epileptic medications, and major depressive diso...
Join CardioNerds EP Council Chair Dr. Naima Maqsood and Episode Lead Dr. Jeanne De Lavallaz as they discuss the results of the ARREST-AF Trial with expert faculty Dr. Prashanthan Sanders and Dr. Mehak Dhande. Audio editing by CardioNerds intern Bhavya Shah. The ARREST-AF trial enrolled 122 patients with a BMI of 27 kg/m2 or greater and at least one cardiovascular risk factor with either paroxysmal or persistent AF and were scheduled to undergo de novo AF ablation. They were randomized to an inte...
Join CardioNerds Heart Failure Section Chair Dr. Jenna Skowronski, episode lead Dr. Merna Hussein, and expert faculty Dr. Milton Packer as they discuss the SUMMIT trial . The SUMMIT trial randomized 731 patients with HFpEF with LVEF ≥ 50% and obesity with BMI ≥ 30 kg/m2 to receive tirzepatide or placebo for at least 52 weeks. The two co-primary endpoints were a composite of time to cardiovascular death or a worsening heart failure event and quality of life measured by the Kansas City Cardiomyopa...
Join CardioNerds Heart Failure Section Chair Dr. Jenna Skowronski, episode lead Dr. Apoorva Gangavelli, and expert faculty Dr. Ronald Witteles as they discuss the Nex-Z trial . This was a phase 1, open-label trial investigating nex-z, a CRISPR-Cas9-based treatment, in 36 patients with transthyretin amyloidosis with cardiomyopathy (ATTR-CM). The primary objectives were aimed at studying the safety and pharmacodynamics of this novel gene-based treatment modality. This episode dives into the nuance...
Join CardioNerds co-founder Dr. Daniel Ambinder, episode lead Dr. Nidhi Patel, and expert faculty Dr. Keith Ferdinand as they discuss the BP ROAD trial . The BP ROAD trial randomized 12,821 patients 50 years of age or older with type 2 diabetes, elevated systolic blood pressure, and an increased risk of cardiovascular disease to receive intensive treatment that targeted a systolic blood pressure of less than 120 mm Hg or standard treatment that targeted a systolic blood pressure of less than 140...
CardioNerds (Dr. Dan Ambinder and guest host, Dr. Pooja Prasad) join Dr. Donny Mattia from Phoenix Children’s pediatric cardiology fellowship, Dr. Sri Nayak from the Mayo Clinic – Arizona adult cardiology fellowship, and Dr. Harrison VanDolah from the University of Arizona College of Medicine – Phoenix Med/Peds program for a sunrise hike of Piestewa Peak, followed by some coffee at Berdena’s in Old Town Scottsdale (before the bachelorette parties arrive), then finally a stroll through the Phoeni...
CardioNerds ( Dr. Dan Ambinder and Dr. Yoav Karpenshif – Chair of the CardioNerds Critical Care Cardiology Council) join Dr. Munim Khan, Dr. Shravani Gangidi, and Dr. Rachel Goodman from Tufts Medical Center’s general cardiology fellowship program for hot pot in China Town in Boston. They discuss a case involving a patient who presented with stress cardiomyopathy leading to cardiogenic shock. Expert commentary is provided by Dr. Michael Faulx from the Cleveland Clinic. Notes were drafted by Dr. ...
In this episode, CardioNerds Dr. Gurleen Kaur and Dr. Akiva Rosenzveig are joined by Cardio-Rheumatology experts, Dr. Brittany Weber and Dr. Michael Garshick to discuss treating inflammation, delving into the pathophysiology behind the inflammatory hypothesis of atherosclerotic cardiovascular disease and the evolving data on anti-inflammatory therapies for reducing ASCVD risk, with insights on real-world implementation. Show notes were drafted by. Dr. Akiva Rosenzveig. This episode was produced ...
The following question refers to Sections 7.3.3 and 7.3.6 of the 2022 ACC/AHA/HFSA Guideline for the Management of Heart Failure. The question is asked by Palisades Medical Center medicine resident & CardioNerds Academy Fellow Dr. Maryam Barkhordarian , answered first by UTSW AHFT Cardiologist & CardioNerds FIT Ambassador Dr. Natalie Tapaskar , and then by expert faculty Dr. Robert Mentz . Dr. Mentz is associate professor of medicine and section chief for Heart Failure at Duke University...
The following question refers to Sections 7.4 and 7.5 of the 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure. The question is asked by the Director of the CardioNerds Internship Dr. Akiva Rosenzveig , answered first by Vanderbilt AHFT cardiology fellow Dr. Jenna Skowronski , and then by expert faculty Dr. Randall Starling . Dr. Starling is Professor of Medicine and an advanced heart failure and transplant cardiologist at the Cleveland Clinic where he was formerly the Section Head...
In this episode, Dr. Paul Ridker, a pioneer in the field of cardiovascular inflammation, joins the CardioNerds ( Dr. Gurleen Kaur , Dr. Richard Ferraro , and Dr. Nidhi Patel ) to discuss the evolving landscape of inflammation as a key factor in cardiovascular risk reduction. The discussion dives into the importance of biomarkers like high-sensitivity C-reactive protein (hs-CRP) in guiding treatment strategies, the insights gleaned from landmark trials like the JUPITER and CANTOS studies, and the...
The following question refers to Section 7.4 of the 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure. The question is asked by the Director of the CardioNerds Internship Dr. Akiva Rosenzveig , answered first by Vanderbilt AHFT cardiology fellow Dr. Jenna Skowronski , and then by expert faculty Dr. Clyde Yancy . Dr. Yancy is Professor of Medicine and Medical Social Sciences, Chief of Cardiology, and Vice Dean for Diversity and Inclusion at Northwestern University, and a member of t...
In this episode, Dr. Gurleen Kaur (Cardiology FIT at Brigham and Women’s Hospital and APD of the CardioNerds Academy) and Dr. Diane Masket (Medicine Resident at the University of Chicago Northshore and CardioNerds Academy Intern) discuss with Dr. Minnow Walsh (Medical Director of the Heart Failure and Cardiovascular programs at Ascension St. Vincent Heart Center in Indianapolis) about her personal and professional journey in Cardiology. They discuss Dr. Walsh’s authorship of the recent ACC state...
The following question refers to Sections 2.1 and 4.2 of the 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure. The question is asked by CardioNerds Academy Intern Dr. Adriana Mares , answered first by CardioNerds FIT Trialist Dr. Christabel Nyange , and then by expert faculty Dr. Shelley Zieroth . Dr. Zieroth is an advanced heart failure and transplant cardiologist, Head of the Medical Heart Failure Program, the Winnipeg Regional Health Authority Cardiac Sciences Program, and an A...
CardioNerds ( Dr. Dan Ambinder and Dr. Rick Ferraro ) join Dr. Mansi Oberoi and Dr. Mohan Gudiwada from the University of Nebraska Medical Center discuss a case of constrictive pericarditis. Expert commentary is provided by Dr. Adam Burdorf , who serves as the Program Director for the Cardiovascular Medicine Fellowship at the University of Nebraska Medical Center. The case discussed involves a 76-year-old woman with a history of monoclonal gammopathy of undetermined significance, chronic obstruc...
Dr. Amit Goyal , along with episode chair Dr. Dinu Balanescu (Mayo Clinic, Rochester), and FIT leads Dr. Sonu Abraham (University of Kentucky) and Dr. Natasha Vedage (MGH), dive into the fascinating topic of channelopathies with Dr. Michael Ackerman , a genetic cardiologist and professor of medicine, pediatrics, and pharmacology at Mayo Clinic, Rochester, Minnesota. Using a case-based approach, they review the nuances of diagnosis and treatment of channelopathies, including Brugada syndrome, cat...
