UCSF researchers June Chan and Stacey Kenfield share evidence-based strategies for improving prostate cancer outcomes through exercise and diet. They highlight studies showing that physical activity—including resistance and high-intensity interval training—is linked to lower risk of prostate cancer progression and death. They discuss plant-based diets, dietary indices, and specific foods like tomatoes, fish, and nuts, along with the benefits of substituting plant oils for butter. Their analysis ...
Aug 03, 2025•33 min
Dr. Steven Seyedin presents an overview of PSA recurrence and risk factors for assessment. A PSA test is a blood test used to detect prostate-specific antigen (PSA) levels in the blood, which can be elevated in cases of prostate cancer and is a common screening tool. He explains how PET, CT, and MRI work, highlighting the precision of PSA PET in detecting cancer spread by targeting PSA proteins on tumor cells. This imaging method combines PET and CT to reveal metastatic disease with greater accu...
Jul 28, 2025•13 min
UCSF’s Dr. Cornelia Ding demystifies the prostate cancer pathology report and explains how to read and understand it. The report contains five key sections: patient information, diagnosis and comments, gross description, and any addendums or amendments. It serves multiple purposes—as a medical, legal, and clinical communication tool—and often contains technical language not written for patients. Dr. Ding walks through important terminology such as Gleason score, Grade Groups, and specific diagno...
Jul 18, 2025•15 min
Prostate cancer remains the most commonly diagnosed cancer and second leading cause of cancer death among men in the U.S., with evolving screening and treatment practices reshaping care in 2025. UCSF's Dr. Matthew Cooperberg highlights a shift away from overdiagnosis and overtreatment of low-risk cancers, focusing instead on identifying aggressive disease through tools like MRI and advanced biomarker tests. A new “smarter screening” model now guides primary care, recommending long testing interv...
Jul 16, 2025•13 min
Dr. Hao Nguyen presents focal therapy as a promising treatment option for carefully selected prostate cancer patients, especially those with intermediate-risk, localized disease. Unlike whole-gland treatments, focal therapy targets only the tumor while preserving healthy tissue, reducing the risk of side effects like urinary or sexual dysfunction. UCSF offers multiple approaches—high-intensity focused ultrasound, cryotherapy, and irreversible electroporation—selected based on tumor location and ...
Jul 07, 2025•10 min
UCSF oncologist Dr. Jonathan Chou discusses how genetics and genomics are transforming the diagnosis and treatment of prostate cancer. He explains how inherited and acquired mutations—especially in DNA repair genes like BRCA2—can impact both cancer risk and treatment decisions. Dr. Chou outlines how UCSF researchers use tumor and blood-based biopsies to identify key mutations and genomic features that help tailor care for each patient. Examples include how genomic scores can predict response to ...
Jun 30, 2025•10 min
UCSF's Dr. Rahul Aggarwal explains the role of clinical trials in advancing prostate cancer treatment and how trial design is evolving to match today’s more personalized approaches. He highlights how UCSF has contributed to major prostate cancer therapies and emphasizes the importance of genetic and genomic testing in identifying suitable trials for each patient. Dr. Aggarwal explains the different trial phases, clarifies common myths—such as concerns about placebos—and stresses that trials are ...
Jun 26, 2025•10 min
William Lowry, Ph.D., discusses manipulating metabolic pathways in hair follicle stem cells to inhibit tumorigenesis. By blocking glycolysis and glutamine lysis simultaneously, they observed tumor regression, highlighting the complex interplay between metabolism and cancer. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39256]
Jun 05, 2025•43 min
Scientists, leaders, and patients discuss the intersection of cutting-edge science and real-world impact. They explore the importance of patient perspectives in shaping medical advancements and how collaboration fuels groundbreaking research. Key scientific achievements in areas like regenerative medicine, cancer therapies, and space biology are highlighted. The group emphasizes the need for scientists to engage more with the public—through social media and media appearances—to help people under...
May 02, 2025•1 hr 13 min
The infections disease landscape is constantly changing - challenging our standard treatments. Can new - as well as ancient - therapies be the answer? Hear from experts on the cutting edge of phage therapy, HIV/AIDS research and cancer care about what is on the horizon to improve human health. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39982]
Nov 30, 2024•56 min
Examine how what we eat and how we live can promote wellness, enhance immunity, combat age-related diseases, and promote longevity. Gordon Saxe, M.D., Ph.D., and Anthony Lim, M.D., J.D., share a timeless perspective, supported by their own research and clinical experience, on how optimal nourishment, purposeful reflection, health movement, and generosity of spirit can improve age-related conditions and slow the aging process. They present evidence-based recommendations for diet and lifestyle, as...
Nov 26, 2024•1 hr 40 min
Curious about the secret to staying young? Rob Signer shares insights into how our bodies age, focusing on the role of stem cells and a critical protein called HSF1 that helps them cope with stress. Signer explores the delicate balance of keeping these cells healthy without increasing cancer risk and highlighted some promising progress in enhancing the cells' ability to manage waste. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39980]
Oct 28, 2024•21 min
As part of the 2024 Prostate Cancer Patient Conference, Dr. Eric Small discusses systemic therapy treatment in advanced prostate cancer, including AR-targeted therapy. The presentation includes definitions of disease states, categories of treatment types, and standards in treatment selection. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 39768]
Jun 27, 2024•22 min
As part of the 2024 Prostate Cancer Patient Conference, Dr. David Oh presents on the use of immunotherapy as a treatment in advanced prostate cancer, including describing how immunotherapy works, possible side effects, and options available currently. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 39770]
Jun 14, 2024•13 min
As part of the 2024 Prostate Cancer Patient Conference, Dr. Matthew Cooperberg discusses surgery as treatment for localized prostate cancer, including risk stratification, how prostatectomy is performed, surgery outcomes and potential side effects. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 39758]
Jun 07, 2024•18 min
As part of the 2024 Prostate Cancer Patient Conference, Drs. Julian Hong and Eric Small discuss oligometastatic prostate cancer and its management with radiation and systemic therapies. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 39766]
Jun 05, 2024•18 min
As part of the 2024 Prostate Cancer Patient Conference, patient advocate Stan Rosenfeld leads a panel discussion including Dr. Benjamin Breyer, patients, and their partners, on living with prostate cancer. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 39773]
Jun 04, 2024•37 min
As part of the 2024 Prostate Cancer Patient Conference, Dr. Rahul Aggarwal reviews emerging treatment approaches for advanced prostate cancer, including developments for antibody-drug conjugates, immunotherapy (T cell engagers), targeted radiation, and targeting Androgen Receptor Signaling. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 39772]
Jun 01, 2024•9 min
As part of the 2024 Prostate Cancer Patient Conference, Dr. Thomas Hope presents information on PSMA-PET and discusses imaging in the evaluation of biochemical recurrence in prostate cancer. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 39762]
May 29, 2024•19 min
As part of the 2024 Prostate Cancer Patient Conference, Dr. Terence Friedlander discusses bone health in advanced prostate cancer. He reviews normal bone health and how it is affected by prostate cancer, defines important terms, and shares recommendations for optimizing bone health in prostate cancer. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 39771]
May 25, 2024•21 min
As part of the 2024 Prostate Cancer Patient Conference, Dr. Hao Nguyen discusses focal therapy as a choice of therapy in patients with low and intermediate risk prostate cancer at high risk for progression. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 39760]
May 22, 2024•15 min
As part of the 2024 Prostate Cancer Patient Conference, Dr. Eric Small reviews Androgen Deprivation Therapy, including choices of agents, side effects, considerations in timing, duration, intensity of therapy, and discusses interpretation of clinical trial results. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 39756]
May 21, 2024•32 min
As part of the 2024 Prostate Cancer Patient Conference, Dr. Mack Roach discusses the phenomenon of “biochemical recurrence” and approaches to risk assessment, following treatments for localized prostate cancer. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 39761]
May 16, 2024•27 min
As part of the 2024 Prostate Cancer Patient Conference, Dr. Julian Hong discusses radiation therapy as treatment for prostate cancer, including potential side effects, considerations in decision making, the radiation oncology care path. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 39759]
May 11, 2024•14 min
As part of the 2024 Prostate Cancer Patient Conference, Drs. June Chan and Stacey Kenfield present recommendations for diet and exercise based in research with prostate cancer patients. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 39767]
May 10, 2024•34 min
As part of the 2024 Prostate Cancer Patient Conference, Dr. Ivan de Kouchkovksky discusses the use of both chemotherapy and radioligand therapy, including a “theranostic” approach, in metastatic treatment resistant prostate cancer. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 39769]
May 08, 2024•12 min
As part of the 2024 Prostate Cancer Patient Conference, Dr. Jonathan Chou discusses individual genetics in the risk of developing prostate cancer, genomic testing to distinguish indolent verses more aggressive disease, and genomic testing to determine best treatment for individual patients. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 39755]
May 05, 2024•27 min
This program demonstrates how to exercise when you don't have a great amount of time or energy. Natalie Marshall, MD, also discusses how to overcome barriers to daily exercise. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 38814]
May 03, 2024•9 min
As part of the 2024 Prostate Cancer Patient Conference, Dr. Kevin Shee presents a comprehensive overview of active surveillance in managing localized prostate cancer. Drawing from the extensive institutional database with over 9,000 participants at UCSF, Dr. Shee highlights groundbreaking insights into the field. From exploring the safety of active surveillance in younger men to investigating the potential of prostate MRI as a biopsy alternative, you'll gain valuable insights into treatment deci...
May 02, 2024•16 min
As part of the 2024 Prostate Cancer Patient Conference, Dr. Samuel Washington summarizes the burden of prostate cancer, updates in early detection guidelines, treatment options, and discusses life after treatment. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 39754]
May 01, 2024•12 min
