CRACKCast E162 – Opioids

Core questions:

1. List 6 commonly abused opioids (Table 156:1)
2. Describe the opioid toxidrome (list opioid effects on Neuro, Resp, Ophtho, CV, GI, Derm)
3. List opioid preparations associated with the following presentations:

1. Long QTc →
2. Prolonged QRS →
3. Seizures →
4. Hallucinations →)
5. Sensorineural hearing loss →
6. Serotonin syndrome →

1. i) What is the dose of narcan? ii) What is the duration of action? iii) How do you administer a narcan infusion?
2. What opioid overdoses/ingestions need longer than 6 hours of observation?
3. What is the clinical presentation of opioid withdrawal?
4. What are risk factors for opioid withdrawal?
5. List 3 medications effective for opioid withdrawal.
6. What is the number one killer of people under 50?
7. What is Suboxone?
8. How do you do a Suboxone induction?

WiseCracks:

1. List 5 ddx for opioid intoxication (CNS + resp depression, + miosis).
2. What opioids don't cause miosis?
3. Risk factors for opioid overdose?
4. What is NAPE? Narcan induced pulmonary edema.
5. Difference between a "body packer" and "body stuffer"?