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Breakpoints

Society of Infectious Diseases Pharmacistssidp.pinecast.co
The SIDP Podcast
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Episodes

#102 – Oh, the Places Stewardship Will Go! Best Practices for Outpatient Antibiotic Stewardship and Transitions of Care

In this episode, Drs. Erica Stohs, Ryan Stevens, and Jame McCrae join Dr. Megan Klatt to discuss antimicrobial stewardship practices at transitions of care and in the outpatient setting. Hear from the experts on how to establish programs in this space, best practices for data/reporting, and other tips for stewardship intervention. Follow us on Instagram! @breakpointspodcast_sidp References: Pharmacist-Driven Transitions of Care Practice Model for Prescribing Oral Antimicrobials at Hospital Disch...

Aug 23, 20241 hr 10 minEp. 102

#101 – BLING III: Does Continuous Infusion Make the Whole Place Shimmer

Join Prof Jason Roberts and Dr. Erin McCreary for this episode dedicated to discussing the results of the BLING III trial, which explored the use of continuous versus intermittent infusion of a beta-lactam antibiotic in critically ill patients. Reference: Continuous vs Intermittent β-Lactam Antibiotic Infusions in Critically Ill Patients With Sepsis: The BLING III Randomized Clinical Trial. 10.1001/jama.2024.9779...

Aug 02, 20241 hr 2 minEp. 101

#100 – Tackling Tetracyclines: Breakpoints 100th Episode!

Drs. Jeffrey Pearson and Jason Pogue join Dr. Jeannette Bouchard as they take on all things tetracyclines. Starting with tetracycline, they walk through differences between each generation and drug in this class, from dosing all the way to pertinent resistance mechanisms. You will not want to miss out on this one! This podcast was supported by an unrestricted grant from Paratek Pharmaceuticals Inc. References: Omadacycline for Mycobacterium abscessus full case series data set: 10.1128/aac.00824-...

Jul 26, 20241 hr 24 minEp. 100

#99 – Don’t be CRABby: Acinetobacter baumannii review

Drs. Yohei Doi and Emily Heil join Dr. Erin McCreary to dive into one of the most requested topics from our listeners and something that is consistently confusing in clinical practice: Acinetobacter baumannii! Hear from experts on their experience with treating this tricky organism and their thoughts on best approaches when you are presented with CRAB. Listen to Breakpoints on iTunes , Overcast , Spotify , Listen Notes , Player FM , Pocket Casts , TuneIn , Blubrry , RadioPublic , or by using our...

Jun 28, 20241 hr 8 minEp. 99

#98 – Uncomplicated UTIs: Getting Uncomfortable with Uncertainty

Breakpoints delves into uncomplicated UTIs, featuring experts who discuss the limitations of urinalysis and the need for clinical diagnosis, especially in diverse patient populations. The episode examines the evolving definitions of UTI, including the "continuum of UTI," and explores innovative approaches like "pill-in-pocket" strategies. It also highlights the challenges of current treatment options, new antibiotics in the pipeline, and the critical unmet needs in prevention and diagnostic certainty for better patient care.

May 24, 20241 hr 13 minEp. 98

#97 – Hot Topics: What Did You Miss in Infectious Diseases in 2023-2024 (LIVE from MAD-ID)

In this special LIVE podcast episode, Drs. Emily Heil (@emilyheil) and Mandee Noval (@MandeeNoval) present the latest and greatest in ID literature from MAD-ID 2024 (@MAD_ID_ASP) in Orlando, FL. They cover everything from ECCMID late breakers to stewardship to the best things to come out of a good old shortage! You won’t want to miss this one! Google Drive to Slides from Live Session: https://drive.google.com/file/d/1L4zq0ZC5LW9cCySE0AiJL7m8qDxS9MGM/view?usp=sharing Submit your 100th Episode vid...

May 17, 20241 hr 27 minEp. 97

#96 – The Tortured Stewards & Surgeons Department

Episode Notes The Society of Infectious Diseases Pharmacists is excited to invite you to the first ever meeting (via Breakpoints) of The Tortured Stewards & Surgeons Department. Today’s agenda items: optimal management of perioperative antibiotics and prevention of surgical site infections. Drs. Trisha Peel (@DrTrishaPeel), Michael Calderwood (@CalderwoodMD) and Patch Dellinger join Dr. Jillian Hayes (@thejillianhayes) to discuss some of the controversies we encounter while managing antibiot...

Apr 19, 20241 hr 6 minEp. 96

#95 – A to Z on R&D: Challenges and Solutions for Sustained Antimicrobial Drug Development

In this episode, Drs. Helen Boucher (@hboucher3), Ramy Elshaboury, and Mike Dudley (@MikeMNDudley) join host, Megan Klatt (@MeganKlatt3), to discuss barriers to antimicrobial drug development, potential incentives and legislation to promote market growth, and what we can do to ensure the antimicrobial pipeline doesn’t run dry. Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About X: @SIDPharm ( https://twitter.com/SIDPharm ) Instagram: @SIDPharm ( https://www.in...

Mar 29, 20241 hr 2 minEp. 95

#94 – Lock, Stock, & Sterilize: Strategies to Optimize Antimicrobial Lock Therapy & Prevent/Treat Catheter-Related Bloodstream Infections

It's time to arm yourselves with all the resources on antimicrobial locks! Join our experts, Drs. Louise-Marie Oleksiuk (@CanRowPharm), Nasia Safdar (@NasiaSafdar), Joel Topf (@kidney_boy), and our wonderful host, Dr. Julie Justo (@julie_justo), to discuss the ins and outs of antimicrobial locks and how to implement them! Funding for this podcast was provided by CorMedix Inc Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About X: @SIDPharm ( https://twitter.com...

Mar 22, 20241 hr 5 minEp. 94

#93 – Global, Live Journal Club: Ceftobiprole for Complicated Staphylococcus aureus Bacteremia (ERADICATE Study)

Drs. Thomas Holland and Vance Fowler (@VanceFowler5) join Drs. Steven Tong (@syctong) and Erin McCreary (@ErinMcCreary) to discuss the ERADICATE study and the role of ceftobiprole for the treatment of complicated Staphylococcus aureus bacteremia. This session was recorded live on Tuesday, February 6th, 2024 featuring an international audience. Listen to Breakpoints on iTunes , Overcast , Spotify , Listen Notes , Player FM , Pocket Casts , TuneIn , Blubrry , RadioPublic , or by using our RSS feed...

Feb 23, 202458 minEp. 93

#92 – Antibiotic Alchemy: Metallo-Beta-Lactamases

Drs. Robert Bonomo, Ryan Shields (@ryankshields), and Erin McCreary (@ErinMcCreary) deep dive into the world of metallo-beta-lactamases. This riveting discussion is full of the nerdiest pub trivia nuggets and the “must know” details of novel beta lactams and beta-lactamase inhibitors, and their uses for MBLs. Funding for this podcast was provided by Shionogi Inc. Listen to Breakpoints on iTunes , Overcast , Spotify , Listen Notes , Player FM , Pocket Casts , TuneIn , Blubrry , RadioPublic , or b...

Feb 02, 20241 hr 11 minEp. 92

#91 – Teamwork Makes the Dream Work: Preparation Pearls for Stewardship and Microbiology Lab Accreditation Updates

New accreditation standards making your head spin? Are you stressed and don’t know where to start? Well, on this episode of Breakpoints Drs. Arjun Srinivasan and Jose Alexander (Alex) join Luis Plaza from Let’s Talk Micro (@letstalkmicro1) and Dr. Jeannette Bouchard (@jlbouchard001) to breakdown what you need to know and where to start when it comes to the NHSN Antimicrobial Resistance (AR) module and the new College of American Pathologist’s standards. Listen to Breakpoints on iTunes , Overcast...

Jan 19, 20241 hr 6 minEp. 91

#90 – IDWeek 2023 Recap: Pipeline Agents and Clinical Trials That May Change Your Practice

We are back with more exciting IDWeek 2023 content! If you listened to the last episode and want more? Than look no further. Join your Breakpoints hosts, Drs. Erin McCreary (@ErinMcCreary), Julie Ann Justo (@julie_justo), and Jeannette Bouchard (@jlbouchard001) for a review of key pipeline agents at IDWeek and highlights from everyone’s favorite session “Clinical Trials That May Change Your Practice”. Listen to Breakpoints on iTunes , Overcast , Spotify , Listen Notes , Player FM , Pocket Casts ...

Jan 05, 20241 hr 3 minEp. 90

#89 – IDWeek 2023 Recap: Late Breaking Clinical Trials

Need help narrowing down your IDWeek re-watch content? Or maybe you were unable to make IDWeek so you want the pharmacy driven highlights? Well, look no further, Breakpoints has what you need! Join your Breakpoints hosts, Drs. Erin McCreary (@ErinMcCreary), Julie Ann Justo (@julie_justo), and Jeannette Bouchard (@jlbouchard001) for a review of some of the late breaking clinical trials presented at IDWeek 2023. Listen to Breakpoints on iTunes , Overcast , Spotify , Listen Notes , Player FM , Pock...

Dec 22, 20231 hr 15 minEp. 89

#88 – Dosing Consult: Can we BID farewell to Q8H Metronidazole?

Drs. Nicholas Torney (@NPT_PharmD) and Sunish Shah join Dr. Jeannette Bouchard (@jlbouchard001) to discuss our next topic in our Dosing Consult series: BID vs TID dosing for metronidazole. Deep dive into the PK/PD and real-world application of this switch with experts in this dosing strategy. References: Addition of anaerobic coverage in biliary infections: Addition of anaerobic coverage for treatment of biliary tract infections: a propensity score-matched cohort study Eggerthella lenta and Pipe...

Dec 01, 202332 minEp. 88

#87 – We Love T Cells: Updates in Cytomegalovirus

Dr. Ajit Limaye and Dr. Camille Kotton (@KottonNelson) join Dr. Erin McCreary (@ErinMcCreary) to discuss fascinating updates in the CMV space including new RCTs for prevention, vaccines, and more! Learn why a little "hair of the dog" might be a good thing, how great T cells are, and the trials we still need. References: CAPSIL study: Effect of Preemptive Therapy vs Antiviral Prophylaxis on Cytomegalovirus Disease in Seronegative Liver Transplant Recipients With Seropositive Donors: A Randomized ...

Nov 17, 20231 hr 21 minEp. 87

#86 – The Robin to Your Batman: Ensuring Adequate Beta-lactamase Inhibitor Exposure to Restore Beta-lactam Activity

Episode Notes Drs. Paul Ambrose and Michael Dudley (@MikeMndudley) join Dr. Julie Ann Justo (@julie_justo) for a review of beta-lactamase inhibitor (BLI) pharmacokinetics & pharmacodynamics. They discuss factors affecting BLI’s restorative activity, the convoluted math behind establishing exposure-response relationships for BLIs, some geeky medicinal chemistry, and a little-known easter egg in the published literature. Learn more about the Society of Infectious Diseases Pharmacists: https://...

Oct 20, 20231 hr 20 minEp. 86

#85 – Who You Gonna Call? Mythbusters! Antibiotic Myths for Infectious Diseases Clinicians

Episode Notes Drs. Jason Gallagher (@JGPharmD) and Melissa Johnson (@IDPharmacist) join Dr. Erin McCreary (@ErinMcCreary) to discuss one of the most talked about papers of the year: Antibiotic Myths for the Infectious Diseases Clinician. Tune in to hear these common myths debunked! Antibiotic Myths for the Infectious Diseases Clinician: https://academic.oup.com/cid/advance-article-abstract/doi/10.1093/cid/ciad357/7194976?redirectedFrom=fulltext Learn more about the Society of Infectious Diseases...

Sep 15, 20231 hr 1 minEp. 85

#84 – Antimicrobial Stewardship and Disaster Medicine: Perspectives from Ukraine

Episode Notes In this special episode of Breakpoints, pharmacist Hailie Uren joins Dr. Erin McCreary (@ErinMcCreary) to talk about the current practice of medicine in Ukraine, including the extremely drug-resistant war wound infections she frequently encounters. You won’t want to miss this amazing insight, and can support UK-Med in Ukraine here: https://www.uk-med.org/donate-now Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm ( https://t...

Aug 18, 202344 minEp. 84

#83 – Dosing Consult: Sulfamethoxazole/trimethoprim

Episode Notes In what has been described on Twitter as the “doing your own taxes of medicine,” Drs. Emily Heil (@emilylheil) and Andrew Fratoni (@AFratty) join Dr. Jillian Hayes (@thejillianhayes) to break down the ins and outs of sulfamethoxazole/trimethoprim dosing! Tune in for a discussion on the use of this agent for methicillin-resistant Staphylococcus aureus , gram-negatives, pneumocystis, and Stenotrophomonas maltophilia. References: Twitter Thread re: Bactrim dosing: https://twitter.com/...

Jul 21, 202353 minEp. 83

#82 – ID Literature Year in Review (LIVE from MAD-ID)

Episode Notes In this special LIVE podcast episode, Drs. Jason Pogue (@jpogue1) and Erin McCreary (@Erin McCreary) present from MAD-ID 2023 (@MAD_ID_ASP) and give a rundown of some of the best ID papers, abstracts, studies, and other cool stuff from late 2022 and early 2023! They cover everything from #ECCMID2023 late breakers to published RCTs to stewardship (but NOT COVID-19!). Download the slides to view as you listen along here: https://drive.google.com/file/d/130YsgVg9J9di41WVKnB3tBhScYNujU...

Jun 23, 20231 hr 14 minEp. 82

#81 – Making the Right Choice Easy: Antimicrobial Stewardship in the Emergency Department

Episode Notes Drs. Zack Nelson (@zacroBID), Alison Dittmer, and Michael Pulia (@DrMichaelPulia) join Dr. Jillian Hayes (@thejillianhayes) to discuss the ins and outs of antimicrobial stewardship in one of the busiest parts of the hospital: the emergency department! Tune in for a discussion on communication considerations in the ED, the role of lipoglycopeptides for common gram-positive syndromes, and a rapid-fire round discussing common stewardship interventions. This podcast was supported by an...

Jun 16, 20231 hr 9 minEp. 81

#80 – Weighting on a Miracle: Understanding Unknowns of Dosing Children and Adults with Obesity

Episode Notes Drs. Kate Kyler (@kedkyler) and Amit Pai (@DosingMatters) join Dr. Jeannette Bouchard (@jlbouchard001) for a discussion on dosing antibiotics in children and adults affected by obesity! Learn when practitioners should be concerned about drug dosing, what disease states and populations matter most, when we should explore TDM, and more! Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm ( https://twitter.com/SIDPharm ) Instagram...

Jun 02, 202338 minEp. 80

#79 – HAP & VAP: Let’s Clear the Air

Episode Notes Drs. Dahlia Blake (@dblake096), Owen Albin (@owenralb), and Ryan Rivosecchi join Dr. Erin McCreary (@ErinMcCreary) for a discussion on HAP and VAP! Tune in for a review of the role of dual anti-pseudomonal coverage, optimal anti-MRSA therapy, duration of therapy, and more! This funding for this episode was provided by Shionogi Inc. Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm ( https://twitter.com/SIDPharm ) Instagram: @...

May 26, 20231 hr 21 minEp. 79

#78 – New Therapies in HIV: The Long Road to Long-acting Antiretrovirals - Are We There Yet?

Episode Notes Drs. Emily Kirkpatrick, Paul Sax, and Jill Strayer join Dr. Rachel Britt to discuss their experiences using injectable long-acting antiretrovirals, especially cabotegravir/rilpivirine, in their clinics. Listen to learn not only about logistical challenges with these drugs, but also creative solutions to overcome them. Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm ( https://twitter.com/SIDPharm ) Instagram: @SIDPharm ( htt...

Apr 28, 202358 minEp. 78

#77 – Breakpoints Talks Breakpoints: Non-fermenters

Episode Notes Drs. Jim Lewis, Mike Satlin (@MSatlin) and Jason Pogue (@jpogue1) are back with Dr. Erin McCreary (@ErinMcCreary) for the grand finale of our five-episode miniseries all about breakpoints! Join our panelists for a great discourse on breakpoint updates for non-fermenters. Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm ( https://twitter.com/SIDPharm ) Instagram: @SIDPharm ( https://www.instagram.com/sidpharm/ ) Facebook: htt...

Apr 21, 202340 minEp. 77

#76 – Breakpoints Talks Breakpoints: Fluoroquinolones

Episode Notes Drs. Jim Lewis, Mike Satlin (@MSatlin) and Jason Pogue (@jpogue1) are back with Dr. Erin McCreary (@ErinMcCreary) for episode four of a five-episode miniseries all about breakpoints! Join our panelists for a magically delicious episode all about breakpoint updates on fluoroquinolones. Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm ( https://twitter.com/SIDPharm ) Instagram: @SIDPharm ( https://www.instagram.com/sidpharm/ )...

Apr 14, 202334 minEp. 76

#75 – Breakpoints Talks Breakpoints: Aminoglycosides

Episode Notes Drs. Jim Lewis, Mike Satlin (@MSatlin) and Jason Pogue (@jpogue1) are back with Dr. Erin McCreary (@ErinMcCreary) for episode three of a five-episode miniseries all about breakpoints! Join our panelists as they discuss breakpoint updates on aminoglycosides. Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm ( https://twitter.com/SIDPharm ) Instagram: @SIDPharm ( https://www.instagram.com/sidpharm/ ) Facebook: https://www.faceb...

Apr 07, 202341 minEp. 75

#74 – Breakpoints Talks Breakpoints: Piperacillin/tazobactam

Episode Notes Drs. Jim Lewis, Mike Satlin (@MSatlin) and Jason Pogue (@jpogue1) are back with Dr. Erin McCreary (@ErinMcCreary) for episode two of a five-episode miniseries all about breakpoints! Join our panelists as they discuss breakpoint updates on piperacillin/tazobactam. Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm ( https://twitter.com/SIDPharm ) Instagram: @SIDPharm ( https://www.instagram.com/sidpharm/ ) Facebook: https://www...

Mar 31, 202338 minEp. 74

#73 – You’re a Breakpoint, Harry: Magical Insights from CLSI and USCAST

Episode Notes Drs. Jim Lewis, Mike Satlin (@MSatlin) and Jason Pogue (@jpogue1) join Dr. Erin McCreary (@ErinMcCreary) for episode one of a five-episode miniseries all about breakpoints! Over the next five weeks, our panelists will cover breakpoint updates on piperacillin/tazobactam, aminoglycosides, fluoroquinolones, and non-fermenters. You won’t want to miss this series! Our first episode will tackle questions related to breakpoints themselves – a seemingly mystical art! How does a breakpoint ...

Mar 24, 202356 minEp. 73
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