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Breakpoints

Society of Infectious Diseases Pharmacistssidp.pinecast.co
The SIDP Podcast
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Episodes

#42 – The Level is in the Details: Beta-lactam Therapeutic Drug Monitoring

Erin McCreary (@erinmccreary) discusses clinical rationale behind therapeutic drug monitoring of beta-lactam antibiotics with Veena Venugopalan (@Veena_PharmD), Joseph Kuti, Jason Roberts (@jasonroberts_pk), and Marc Scheetz (IDPharmacometrx). For BCIDP credit, visit https://sidp.org/BCIDP References: https://pubmed.ncbi.nlm.nih.gov/32383061/ 2. https://clicktime.symantec.com/3BcGw6g11AZY2rSUu7KpT1D7Vc?u=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F34136822%2F 3. https://pubmed.ncbi.nlm.nih.gov/33480...

Aug 20, 202156 minEp. 42

#41 – The Gray Zone: Antimicrobial Stewardship in Immunocompromised Hosts

Promoting evidence-based antimicrobial stewardship for patients with immunocompromising conditions can be tricky when they’re often excluded from clinical studies. Dr. Zahra Kassamali Escobar (@ZKEPharmD) explores this gray zone with Dr. Catherine Liu and Dr. Justine Ross (@abella_ross) References: Fluoroquinolone Prophylaxis Bucaneve et al. Levofloxacin to prevent bacterial infection in patients with cancer and neutropenia. N Engl J Med 2005; 353:977-87. DOI: 10.1056/NEJMoa044097 Cullen et al. ...

Jul 16, 2021Ep. 41

#40 – Breakpoints Talks Breakpoints: Microbiology Labs and Stewardship

In this episode, host Dr. Erin McCreary (@erinmccreary) talks all things micro labs and stewardship with Dr. Romney Humphries (@romneyinla), Dr. Mary Hutton (@m3rkat), and Dr. Joseph Lutgring. From cascading results and breakpoint changes, to making connections within and outside of the lab, we hope you listen, laugh, and learn! > Show notes: Mary’s paper: Microbiology Comment Nudge Improves Pneumonia Prescribing - PubMed (nih.gov) CDC Key Activities and Roles for Microbiology Lab Staff in An...

Jun 18, 20211 hr 14 minEp. 40

#39 – A Little More on the Littles: What Adults Should Know about ID Pediatrics

In this rapidfire episode Dr. Erin Weslander (@littlebugdrug), Dr. Laura Bio (@StanfordPedsASP), and Dr. Diana Yu (@dyupharmd) reveal their super-secret ID toolkit to figure out dosing and approaches to treatment in pediatric patients. Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm ( https://twitter.com/SIDPharm ) Instagram: @SIDPharm ( https://www.instagram.com/sidpharm/ ) Facebook: https://www.facebook.com/sidprx LinkedIn: https://www...

May 21, 202117 minEp. 39

#38 – You're KID-ding! Myths in ID Pediatrics

Dr. Erin Weslander (@littlebugdrug), Dr. Laura Bio (@StanfordPedsASP), and Dr. Diana Yu (@dyupharmd) breakdown common myths about antimicrobials in pediatric patients. Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm ( https://twitter.com/SIDPharm ) Instagram: @SIDPharm ( https://www.instagram.com/sidpharm/ ) Facebook: https://www.facebook.com/sidprx LinkedIn: https://www.linkedin.com/company/sidp/...

Apr 23, 202124 minEp. 38

#37 – A Gab about Cab: The Short on Long-Acting Antiretrovirals for HIV

Dr. Fidelia Bernice, Dr. Rodrigo Burgos, and Dr. Neha Pandit, join Breakpoints to discuss the first available long-acting antiretroviral agent, cabotegravir/rilpivirine. Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm ( https://twitter.com/SIDPharm ) Instagram: @SIDPharm ( https://www.instagram.com/sidpharm/ ) Facebook: https://www.facebook.com/sidprx LinkedIn: https://www.linkedin.com/company/sidp/...

Apr 16, 202132 minEp. 37

#36 – Monoclonal Antibodies: Gateway Drugs for Future Care Delivery Models

Dr. Susan Davis (@IDPharmProf), Dr. Emily Spivak (@EmilySpivak), and Dr. Minkey Wungwattana (@minkeyw) join Dr. Erin McCreary (@ErinMcCreary) to discuss individual and shared experiences operationalizing COVID-19 monoclonal antibody therapy across their institutions and states. They tackle big and small hurdles from finding ways to ensure equitable distribution to pronouncing the drug names! This episode was sponsored by an unrestricted grant from Regeneron Pharmaceuticals. Learn more about the ...

Mar 26, 2021Ep. 36

#35 – Oral Beta-Lactams, Are We Serious?

Dr. Jill Cowper (@jillcowper), and Dr. Jesse Sutton, join host Dr. Zahra Kassamali Escobar (@zkePharmD) to discuss the data behind use of oral beta-lactams as step-down therapy for bacteremia and other serious infections. Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm ( https://twitter.com/SIDPharm ) Instagram: @SIDPharm ( https://www.instagram.com/sidpharm/ ) Facebook: https://www.facebook.com/sidprx LinkedIn: https://www.linkedin.com/...

Mar 19, 20211 hr 2 minEp. 35

#34 – The New Scoop on Poop: Updates in the Management of C. difficile infections

Dr. Kevin Garey (@GareyKgarey), Dr. Kelly Reveles (@KellyReveles), Dr. Mandelin Cooper, and host Dr. Rachel Britt (@RachelBPharmD) discuss proposed updates of the IDSA-SHEA C. difficile guidelines, including: fidaxomicin over oral vancomycin as first-line therapy, the roles and logistical hurdles of fecal microbiota transplant, bezlotoxumab, and the pros and cons of prophylaxis. Timestamps 1:16 - Panel introductions 3:19 - Fidaxomicin vs PO vancomycin for first occurrence 7:21 - Fidaxomicin cost...

Feb 19, 2021Ep. 34

#33 – A Lung Time Coming: Controversies in Community Acquired Pneumonia

Join Dr. Elizabeth Covington (@ewood_1875), Dr. Brandon Dionne (@BWDionne), Dr. Jason Pogue (@jpogue1), and Dr. David Ha (@DHpharmd) as they discuss new and old antibiotic therapies for community acquired pneumonia, just how typical are atypicals, what happened to HCAP, and much more! This episode was sponsored by an unrestricted educational grant from Paratek Pharmaceuticals Time stamps: 00:00 Intro, guest bios 03:54 Procalcitonin 10:06 Pneumococcal and legionella antigen testing 16:30 Outpatie...

Jan 15, 2021Ep. 33

#32 – Unsolicited Advice: An Honest Discussion of Burnout in Stewardship

Join Dr. Julie Szymczak @julieszymczak, Dr. Emily Heil @emilylheil, Dr. Zahra Kassamali Escobar @zkepharmd, and Dr. Erin McCreary @erinmccreary, for a discussion on stewardship burnout—what is it, who is at risk for it, and what can we do about it? Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm ( https://twitter.com/SIDPharm ) Instagram: @SIDPharm ( https://www.instagram.com/sidpharm/ ) Facebook: https://www.facebook.com/sidprx LinkedIn...

Dec 18, 20201 hr 1 minEp. 32

#31 – “Mind the Gap”: Antimicrobial Stewardship at Transitions of Care

Antimicrobial stewardship is often an inpatient effort and overlooked at transitions of care. Dr. April Dyer (@aprildyerid) and Dr. Rachel Kenney (@rkenneypharmd) share insight with host Dr. David Ha (@DHpharmD) on current practice and barriers, and strategies for pharmacists to bring antimicrobial stewardship in the discharge process. Episode content: 00:14: Welcome and introductions: 04:39: Project overview: "Developing Patient Safety Outcome Measures and Measurement Tools for Antimicrobial St...

Nov 20, 2020Ep. 31

#30 – Is More Better? The Role of Combination Therapy for MRSA

Host Erin McCreary (@erinmccreary) and expert panelists Dr. Katie Barber (@IDKatieBarb), Dr. Warren Rose (@Warren_E_Rose), and Dr. Steven Tong (@syctong) discuss data from early laboratory work to randomized, clinical trials for various antibiotic combinations used in the treatment of MRSA bacteremia. This was our most requested topic to cover on Breakpoints, and we hope you enjoy! Please complete this brief survey to help us continue to improve Breakpoints content: https://docs.google.com/forms...

Oct 09, 20201 hr 2 minEp. 30

#29 – What You May Have Missed Due to COVID-19: ID Literature Updates 2020 Part 2

Erin McCreary (@erinmccreary) and Ryan Shields (@ryankshields) discuss notable infectious diseases publications from the first half of 2020. Papers discussed: 1) Van Duin D, et al. Lancet Infect Dis. 2020 Jun;20(6):731-741. doi: 10.1016/S1473-3099(19)30755-8. 2) Livermore DM, et al. Clin Infect Dis. 2020 Feb 6;ciaa122. doi: 10.1093/cid/ciaa122. 3) Falcone M, et al. Clin Infect Dis. 2020 May 19;ciaa586. doi: 10.1093/cid/ciaa586. 4) Lodise TP, et al. J Antimicrob Chemother. 2020 May 28;dkaa197. do...

Sep 11, 20201 hr 18 minEp. 29

#28 – What You May Have Missed Due to COVID-19: ID Literature Updates 2020 Part 1

Erin McCreary (@erinmccreary) and Ryan Shields (@ryankshields) discuss notable infectious diseases publications from the first half of 2020! Papers discussed: 1) Rybak MJ, et al. Am J Health Syst Pharm. 2020 May 19;77(11):835-864. doi: 10.1093/ajhp/zxaa036. 2) Scheetz MH. Am J Health Syst Pharm. 2020 May 19;77(11):810-811. doi: 10.1093/ajhp/zxaa076. 3) Alosaimy S, et al. Clin Infect Dis. 2020 July 27;ciaa1039. doi: 10.1093/cid/ciaa1039. 4) Rhee C, et al. Clin Infect Dis. 2020 May 6;ciaa059. doi:...

Sep 04, 20201 hr 15 minEp. 28

#27 – Expert Updates in Gram Negative Resistance: Q&A Session

This is part 2 of a continuing education series produced in partnership with the SIDP Education Center (SIDPEC) on gram-negative bacterial resistance. It features expert speakers, Drs. Keith Kaye (@Keith_S_Kaye) and Kimberly Claeys (@ClaeysKcclaeys) and host Julie Ann Justo (@julie_justo). If you missed part 1 of this series, delivered as a webinar lecture, please go to sidp.org/SIDPEC to view that portion of the series first. In this podcast, our experts answer a collation of > 150 questions...

Jul 31, 20201 hr 18 minEp. 27

#26 – OPAT - The Final Frontier, Part 2

Gain insight into Outpatient Parenteral Antibiotic Therapy (OPAT) practices across the country from Drs. Jessie Ortwine (@jkortwine), Monica Mahoney (@mmpharmd), Keenan Ryan (@keenanconazole), Monica Donnelley (@DonnelleyMonica), and Meera Mehta. Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm ( https://twitter.com/SIDPharm ) Instagram: @SIDPharm ( https://www.instagram.com/sidpharm/ ) Facebook: https://www.facebook.com/sidprx LinkedIn: ...

Jun 19, 202032 minEp. 26

#25 – Remdesivir: Ethical and Practical Considerations for Allocation, Tracking, and More

Drs. Julie Ann Justo (@julie_justo), Erin McCreary (@erinmccreary), and Helen Newland (@helennewland) discuss ethical allocation of Emergency Use Authorization remdesivir for patients with COVID-19. Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm ( https://twitter.com/SIDPharm ) Instagram: @SIDPharm ( https://www.instagram.com/sidpharm/ ) Facebook: https://www.facebook.com/sidprx LinkedIn: https://www.linkedin.com/company/sidp/...

Jun 18, 20201 hr 16 minEp. 25

#24 – OPAT – The Final Frontier, Part 1

Gain insight into Outpatient Parenteral Antibiotic Therapy (OPAT) practices across the country from Drs. Jessie Ortwine (@jkortwine), Monica Mahoney (@mmpharmd), Keenan Ryan (@keenanconazole), Monica Donnelley (@DonnelleyMonica), and Meera Mehta. Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm ( https://twitter.com/SIDPharm ) Instagram: @SIDPharm ( https://www.instagram.com/sidpharm/ ) Facebook: https://www.facebook.com/sidprx LinkedIn: ...

Jun 12, 202025 minEp. 24

#23 – Taking a “BITE” Out of Antibiotic Prescribing: Strategies to Improve Antimicrobial Usage in Dentistry

Dr. Katie Suda (@sudamonas) and Dr. Erinne Kennedy join Dr. Zahra Escobar (@zkepharmd) of the Breakpoints team to discuss strategies to improve antibiotic utilization and forge connections with our dental colleagues to achieve a common goal of improved patient outcomes. Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm ( https://twitter.com/SIDPharm ) Instagram: @SIDPharm ( https://www.instagram.com/sidpharm/ ) Facebook: https://www.facebo...

May 22, 202033 minEp. 23

#22 – Taking a “BITE” Out of Antibiotic Prescribing: The Need for Antimicrobial Stewardship in Dentistry

Dr. Katie Suda (@sudamonas) and Dr. Erinne Kennedy join Dr. Zahra Escobar (@zkepharmd) of the Breakpoints team to discuss why dentists prescribe 1 in 10 of all antibiotics in the United States and how COVID-19 risks are being managed among dentists and other oral health providers. Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm ( https://twitter.com/SIDPharm ) Instagram: @SIDPharm ( https://www.instagram.com/sidpharm/ ) Facebook: https:/...

May 15, 202037 minEp. 22

#21 – Frontline Allies: Emergency Medicine and Critical Care Insights into COVID19

Dr. Jenny Koehl (@jlkoehl), Dr. Karen Berger (@karenccrx), and Dr. Karen Dohr join host Erin McCreary (@erinmccreary) to discuss taking care of patients with COVID-19 in the Emergency Department and Intensive Care Unit. Listen as the team reflects on their first patients, PPE, anticoagulation, corticosteroid controversies, and more! Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm ( https://twitter.com/SIDPharm ) Instagram: @SIDPharm ( ht...

Apr 27, 20201 hr 1 minEp. 21

#20 – What is Happening Right Now? COVID-19 Challenges and Silver Linings

Julie Ann Justo (@julie_justo), Jason Pogue (@jpogue1), and Erin McCreary (@erinmccreary) discuss critically evaluating COVID-19 literature, staying calm in the storm, strategies for team education and communication, and the role of social media in a pandemic. Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm ( https://twitter.com/SIDPharm ) Instagram: @SIDPharm ( https://www.instagram.com/sidpharm/ ) Facebook: https://www.facebook.com/sid...

Apr 13, 20201 hr 2 minEp. 20

#19 – Push and Pull: Combating Antibiotic Resistance from Discovery to Market Reform

Dr. Mike Dudley (@MikeMndudley), President and CEO of Qpex Biopharma, joins Dr. Erin McCreary (@erinmccreary) to discuss the thrills and failures of antibiotic discovery and development along with the critical need for antibiotic market reform. We discuss the complexity of antibiotic resistance in gram-negative pathogens, antibiotic targets, potential market solutions, and more! Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm ( https://t...

Feb 21, 20201 hr 24 minEp. 19

#18 – Waking the Sleeping Giant: Engaging Nurses in Antimicrobial Stewardship

Dr. David Ha (@DHpharmd) interviews Dr. Rita Olans (@RitaOlans) and Dr. Elizabeth Monsees (@eamonsees) about the critical role nurses play in antimicrobial stewardship. They discuss how nursing practice overlaps with stewardship teams, case examples of nurse integration in stewardship in various practice settings, guidance documents, and real-world advice for advancing your stewardship services with nursing collaboration. Learn more about the Society of Infectious Diseases Pharmacists: https://s...

Jan 17, 202047 minEp. 18

#17 – See C. diff: A Discussion on Patient Advocacy

Christian John Lillis, co-founder and Executive Director of the Peggy Lillis Foundation (@peggyfund), joins Erin McCreary (@erinmccreary) to share his mother’s story and discuss opportunities and challenges for patient advocacy and antimicrobial resistance. Get involved with the Peggy Lillis Foundation: https://peggyfoundation.org/get-involved/take-action/ Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm ( https://twitter.com/SIDPharm ) I...

Dec 20, 20191 hr 15 minEp. 17

#16 – 5 Ways Hospital Pharmacists Can Be Antibiotics Aware

Dr. Susan Davis (@IDPharmProf) and Dr. Jason Pogue (@jpogue1) celebrate Antibiotic Awareness Week by discussing the 5 Ways Hospital Pharmacists Can Be Antibiotics Aware, including: verify penicillin allergy, avoid duplicate anaerobic coverage, reassess antibiotic therapy, avoid treatment of asymptomatic bacteriuria, use the shortest effective antibiotic duration. CDC Poster: https://www.cdc.gov/antibiotic-use/community/pdfs/Hospital-Pharmacist-Poster-508.pdf Learn more about the Society of Infec...

Nov 20, 201949 minEp. 16

#15 – CDC Core Elements of Hospital Antibiotic Stewardship Programs: 2019 Update

Dr. Arjun Srinivasan and Dr. Melinda Neuhauser join host Dr. Erin McCreary (@erinmccreary) to discuss the updated Core Elements of Hospital Antibiotic Stewardship Programs from the Centers for Disease Control and Prevention. These updates emphasize the importance of pharmacist and physician co-led stewardship programs and expanding the stewardship team to all hospital groups and departments. CDC Core Elements 2019: https://www.cdc.gov/antibiotic-use/healthcare/pdfs/hospital-core-elements-H.pdf L...

Nov 18, 201954 minEp. 15

#14 – Pumpkin-Spiced Lessons: Phages, Posters, and Paul Sax

Erin McCreary (@erinmccreary) and Ryan Shields (@ryankshields) are joined by Dr. Paul Sax (@PaulSaxMD) to review important updates in HIV care from IDWeek 2019. They also go “rapid fire” through posters and oral abstracts presented at IDWeek 2019, nerd out over genomics, phages, and beta-lactamases, and discuss the new CAP and vancomycin guidelines. Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm ( https://twitter.com/SIDPharm ) Instagra...

Nov 08, 20191 hr 16 minEp. 14

#13 – Provocative Titles and Pro-Con Debates

Erin McCreary (@erinmccreary) and Ryan Shields (@ryankshields) discuss the IDWeek 2019 session "We're Part of the Problem: How ID Killed Antibiotic Development' and other hot topics including pro-con debates, behavioral approaches to antimicrobial stewardship, and more. Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm ( https://twitter.com/SIDPharm ) Instagram: @SIDPharm ( https://www.instagram.com/sidpharm/ ) Facebook: https://www.facebo...

Nov 08, 20191 hr 5 minEp. 13
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