Sarah Banks, Ph.D. explores why Alzheimer's disease affects women differently than men, emphasizing distinct patterns in tau pathology, cognitive testing bias, and treatment response. She explains how women tend to show a rapid buildup of tau during early cognitive decline, which may contribute to their higher prevalence of Alzheimer's. Banks also highlights how common diagnostic tools may overlook symptoms in women and how approved treatments may offer less benefit for them. Her research at UC ...
Aug 07, 2025•5 min
Martin Kampmann, Ph.D., explores how CRISPR screening and induced pluripotent stem cell (iPSC) technology can uncover new insights into neurological diseases such as Alzheimer's. His lab uses CRISPR to identify genes that influence protein aggregation and cellular vulnerability, focusing on neurons, astrocytes, and microglia derived from human stem cells. Kampmann highlights the roles of mitochondria, autophagy, and other cellular pathways in disease progression, emphasizing the importance of un...
Jan 03, 2025•58 min
What can you do today to improve or maintain your brain health? Join Sarah Banks, Ph.D., a leading expert in healthy aging, dementia, and Alzheimer's disease, as she discusses the latest research on the effects of exercise on brain health. Stay informed and proactive about maintaining cognitive function as you age with insights from cutting-edge research. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40062]
Sep 09, 2024•2 min
What can you do today to improve or maintain your brain health? Join Sarah Banks, Ph.D., a leading expert in healthy aging, dementia, and Alzheimer's disease, and discover actionable steps you can take to protect your brain health. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40061]
Aug 29, 2024•10 min
What can you do today to improve or maintain your brain health? Join Sarah Banks, Ph.D., a leading expert in healthy aging, dementia, and Alzheimer's disease, as she discusses the latest research on diet and cognitive decline. Learn how diet, vascular health and inflammation contributes to cognitive function and discover actionable steps you can take to protect your brain health. Stay informed and proactive about maintaining cognitive function as you age with insights from cutting-edge research....
Aug 21, 2024•3 min
What can you do today to improve or maintain your brain health? Sarah Banks, Ph.D., an expert in healthy aging, dementia, and Alzheimer's disease, explores risk factors and corrective tips associated with sleep apnea. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40042]
Aug 15, 2024•3 min
What can you do today to improve or maintain your brain health? Join Sarah Banks, Ph.D., a leading expert in healthy aging, dementia, and Alzheimer's disease, for an in-depth exploration of the latest research on cognitive decline. This comprehensive program delves into the science behind brain health, covering key factors such as exercise, diet, sleep, social engagement, vascular health, hearing loss, and inflammation. Learn how each of these elements contributes to cognitive function and disco...
May 30, 2024•55 min
Claudia H. Kawas, M.D., addresses Alzheimer's disease and related conditions in older adults, noting the challenge of accurate diagnosis and the resemblance of other brain conditions to Alzheimer's. She introduces "resistance" and "resilience," explaining how some individuals remain cognitively intact despite brain changes. Kawas suggests declining dementia risk due to improved vascular health management, emphasizing the complexity of cognitive decline and the need for further research. Series: ...
Mar 29, 2024•49 min
Alzheimer’s disease is a major health crisis that is projected to become an even larger threat in the coming decades. According to the National Institute on Aging, the number of Americans 65 and older with Alzheimer’s could rise from 5.8 million in 2020 to 13.8 million by 2050. Given the severity of this health crisis and the toll it takes on patients, their families and society, we must be prepared today to address the needs of tomorrow. Dean Frank LaFerla of UC Irvine's School of Biological Sc...
Feb 11, 2023•1 hr 23 min
Thomas C. Südhof, M.D., Stanford University, discusses facets of the fundamental cell biology of ApoE and APP analyzed in stem cell-derived human neurons. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38405]
Nov 16, 2022•56 min
Dr. Songi Han, professor in the Department of Chemistry, Biochemistry and Chemical Engineering at UC Santa Barbara, talks about her research into the function of proteins in the body and how changes like protein Tau tangles can lead to neurological diseases like Alzheimer's. Series: "GRIT Talks" [Health and Medicine] [Science] [Show ID: 37869]
Apr 13, 2022•28 min
Tarek Rajji, MD, shares research from current trials combining brain stimulation with interventions including cognitive remediation. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 37598]
Nov 20, 2021•19 min
Dr. Georges Naasan discusses communication difficulties associated with the language syndrome of Alzheimer's Disease. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 37334]
Aug 30, 2021•5 min
Dr. Georges Naasan describes the symptoms seen in the frontal/executive syndrome of Alzheimer's disease. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 37335]
Aug 27, 2021•2 min
Research suggests that listening to or singing songs can provide emotional and behavioral benefits for people with Alzheimer's disease. Dr. Theresa Allison provides an overview of music in the context of dementia and caregiving relationships. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 37150]
Jul 09, 2021•1 hr 21 min
Stem cell research is changing the way Alzheimer's disease is diagnosed and treated. Larry Goldstein, PhD and Doug Galasko, MD join Alysson Muotri, PhD to share the latest findings and what the future may hold. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36805]
Mar 04, 2021•1 hr 45 min
Lawrence S.B. Goldstein, PhD discusses his career in science and his work to understand the molecular basis of neuronal defects in Alzheimer's Disease. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36338]
Oct 10, 2020•44 min
Researcher Alysson Muotri is using stem cells to study everything from autism to the Zika virus. In this excerpt Muotri discusses stem cell and brain organoid research for possible applications to human diseases. Series: "Health Matters" [Health and Medicine] [Show ID: 36301]
Aug 28, 2020•6 min
Interactive immune systems are at the center of cancer and other diseases. Dr. Matthew Krummel explores some lesser-known functions of the immune system related to memory making, arteriosclerosis, and gut health. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 36205]
Jul 31, 2020•6 min
Dr. Aimee Kao discusses key behaviors known to protect brain health. Dr. Kao looks at population trends and wonders if they tell a complete story. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 36154]
Jul 11, 2020•6 min
Dr. Aimee Kao looks at recent news in Alzheimer's Disease therapeutics including drugs in development and the potential of stem cells and genome editing. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 35238]
Dec 07, 2019•55 min
David M. Holtzman, MD of the Washington University School of Medicine discusses the mechanisms underlying neurodegeneration and how microglia and specific microglial genes such as TREM2 influence neurodegeneration in the setting of Aβ and tau pathology. Learn how this line of study may lead to new therapeutics and diagnostic testing for Alzheimer's disease. Series: "Brain Channel" [Health and Medicine] [Education] [Professional Medical Education] [Show ID: 35262]
Oct 08, 2019•52 min
Worldwide 50 million people live with dementia. By 2040 over 70% of them will be living in the developing world. Dr. Shamiel McFarlane explores the social and economic cost of dementia around the world. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 34779]
Aug 30, 2019•1 hr 25 min
There are modifiable behaviors that may reduce the risk factor of Alzheimer's: vascular disease, sedentary lifestyle, depression/stress, diet factors and alcohol. Kaitlin Casaletto talks about the benefits of an active lifestyle and proper nutrition. Then Dr. Joanna Hellmuth looks at how to decode direct-to-consumer interventions - dietary supplements - and the rise of pseudo-medicine for dementia. She explains that supplements may or may not be safe and that manufacturers can make broad claims ...
Aug 27, 2019•1 hr 24 min
Dr. Julio Rojas-Martinez discusses the pharmacological treatment of Alzheimer’s disease now and what is in development. Current approaches pursue early intervention in the dementia phase. Novel emerging strategies will likely accompany anti-amyloid and anti-tau approaches in the future. Then Sarah Dulaney, RN, describe dementia education, support, and non-pharmacological treatment strategies. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 34...
Aug 16, 2019•1 hr 24 min
Alzheimer’s disease is the most common but not the only cause of dementia throughout the lifespan. Dr.Salvatore Spina discusses frontotemporal dementias and how they differ. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 34776]
Aug 05, 2019•1 hr 28 min
Dr. Georges Naasan explores the principal clinical syndromes of Alzheimer's Disease: memory, visual, language and frontal/executive. He also discusses neuropathology, genetic factors and modern biomarkers with colleagues from the UCSF Memory and Aging Center. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 34775]
Jul 27, 2019•1 hr 27 min
Neurologist Dr. Serggio Lanata explores the neurodegenerative disease of the brain, what they have in common and how they differ. alzheimer's is the most common neurodegenerative disease but there are several others including Parkinson's, Huntington Disease and others. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 34774]
Jul 23, 2019•1 hr 30 min
More than 5 million Americans are currently diagnosed with Alzheimer’s disease, and that number is expected to triple by 2050, without prevention or cure. By 2060, the number of Latinos in the United States living with Alzheimer’s disease is projected to increase 832 percent — from 379,000 in 2012, to more than 3.5 million. Find out what UC San Diego is doing to both serve this community and catalyze the research careers of investigators from underrepresented groups. Series: "Brain Channel" [Hea...
Jan 31, 2019•24 min
Alex Figueroa and Dr. Jose Soria-Lopez discuss clinical symptoms of Alzheimer's Disease and the need to include the Latino community in clinical research. Series: "Brain Channel" [Health and Medicine] [Science] [Show ID: 34416]
Jan 24, 2019•19 min
