biosights: January 21, 2013

How cell shape changes unfold

Under certain conditions, cells form protrusions that oscillate rapidly around the cell periphery. Kapustina et al. reveal that these oscillatory protrusions, which may be related to processes involved in amoeboid cell migration, are driven by the cyclic folding and unfolding of the plasma membrane and its underlying actin cortex. This biosights episode presents the paper by Kapustina et al. from the January 7, 2013, issue of The Journal of Cell Biology and includes an interview with lead author Maryna Kapustina (University of North Carolina, Chapel Hill). Produced by Caitlin Sedwick and Ben Short. See the associated paper in JCB for details on the funding provided to support this original research.

Subscribe to biosights via iTunes or RSS View biosights archive

The Rockefeller University Press biosights@rockefeller.edu