biosights: August 5, 2013

Epithelia restored by healing waves

Epithelial cells around the edge of a wound assemble an actomyosin cable that constricts to draw the wound closed, but the events that precede cable formation are largely unknown. Antunes et al. reveal that wounding induces a wave of actomyosin assembly and cell constriction that flows toward the wound edge to promote cable assembly and tissue repair. This biosights episode presents the paper by Antunes et al. from the July 22, 2013, issue of The Journal of Cell Biology and includes an interview with senior author Antonio Jacinto (NOVA, Lisbon, Portugal). Produced by Caitlin Sedwick and Ben Short. See the associated paper in JCB for details on the funding provided to support this original research.

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