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BBC Inside Science

BBC Radio 4www.bbc.co.uk

A weekly programme that illuminates the mysteries and challenges the controversies behind the science that's changing our world.

Episodes

Malaria: what's in it for the mosquito?

Malaria, a disease that infects hundreds of millions of people and kills hundreds of thousands each year. It is caused after a plasmodium parasite is passed from a blood-feeding mosquito into a human host. Subject to much research over hundreds of years, of both host and parasite, one of the evolutionary mysteries has been why the plasmodium so prospers in the mosquito populations in infected areas. Why haven’t mosquitoes’ immune systems learned to fight back for example? In short, what’s in it ...

Nov 25, 202136 min

Yet More Space Junk; COP-up or COP-out; The End of Bias.

Earlier in the week the current ISS crew had to prepare to evacuate after Russia tested an anti-satellite weapon, spreading thousands of high velocity shards of ex-satellite into a reasonably low-earth orbit and potentially endangering many other earth observation and communication satellites of all nations. How can we clear this and all the other debris? BBC Space Correspondent Jonathan Amos tells Gaia Vince about the Russian test and of efforts to de-orbit some other deceased orbital vehicles....

Nov 18, 202137 min

Propane: Keeping Your Cool as the World Warms Around You

How propane might prevent air conditioning and refrigeration becoming an even bigger burden as our planet warms. Also, covid antiviral pills, and how we forgot to breathe properly. The Montreal Protocol is famous for reducing CFC emissions to help protect the Ozone Layer. We only started using things like CFCs as refrigerants in our fridges and air-conditioning because they weren't as flammable as many alternatives. They were mainly replaced by HFCs, though these are also on the way out. The rea...

Nov 11, 202139 min

How Whales Farmed For Food, COP progress, and The Last Stargazers

Gaia Vince hears how blue whales' huge appetites and energetic eating behaviours helped generate more food for themselves. Also, an update from COP26, and Emily Levesque on The Last Stargazers. New research published this week in the journal Nature reveals new insights into blue whales eating habits. Matthew Savoca and colleagues suggest these biggest of marine animals actually eat up to three times the mass of krill previously estimated. And they do this by finding the blooms of krill and using...

Nov 04, 202134 min

Atmospheric Pollutants and Where to Find Them

This week London's Ultra Low Emission Zone was extended to 18 times its previous size. In an effort to cut levels of various nitrogen oxides and other gases dangerous to humans from urban air, cities encouraging lower emission vehicles is a trend soon stretching across the UK and other European countries. But some are sceptical as to their efficacy. Dr Gary Fuller of Imperial College London is author of The Invisible Killer, and has been studying the air in London and elsewhere since these zones...

Oct 28, 202134 min

The Possible Impact of false-negative PCR Tests

As many as 43,000 PCR tests for people living in and around the South West of England could have been wrongly returned as negative recently, thanks to a seemingly unknown error, or errors, at a laboratory near Wolverhampton. For an extraordinarily long time the mistakes went undetected, and every day many hundreds of people who really had Covid, were told they hadn't. To discuss the numbers and difficulty in calculating the full tragic consequences of the events, Marnie Chesterton speaks to Dr D...

Oct 21, 202139 min

Early Alzheimer's Alert

Marnie Chesterton hears of a simple test for the earliest signs of Alzheimer's disease. She finds out about UK scientists using robots to map radiation at Chernobyl, and talks to Merlin Sheldrake about fungi. Roland Pease travels to Bath University to meet scientists who may have developed a way to diagnose Alzheimer's in the earliest stages of the disease. Dr George Stothart, has led the team in the development of this simple 2 minute test. Prof Thomas Scott of Bristol University and team devel...

Oct 14, 202132 min

Surprising choice for Nobel prizes in a pandemic?

This week saw the announcement of the Nobel prizes for physiology or medicine, chemistry and physics. None of them reward research connected with Covid. Roland Pease, science journalist and Nobel watcher, and Gaia Vince discuss the decisions, which some have said are controversial in this pandemic year. The BepiColombo space craft, a joint European and Japanese mission, has just completed its first fly-by of Mercury, after a three year journey. Professor Dave Rothery, a planetary geologist at th...

Oct 07, 202132 min

Covid vaccine boosters; why we don't have a tail; cassowary domestication; Royal Society Science book prize shortlist

Booster vaccines are now being offered to people in England most at risk of Covid, who had their second jab at least 6 months ago. Most people are getting an mRNA vaccine as a booster, mainly the Pfizer one. Dr Andrew Ustianowski, national clinical lead for the UK COVID Vaccine Research Programme, and infectious diseases consultant in Manchester, explains why people are not being offered new vaccines, specifically tweaked to prevent the current highly transmissible delta variant. And he talks ab...

Sep 30, 202133 min

La Palma volcano; wind energy in the UK; origins of SARS-Cov2; Formula 1 safety

Thousands of people have been forced to flee the path of the lava that has been spewing from the Cumbre Vieja volcano on La Palma since Sunday 18th September. Dr Rebecca Williams of Hull University is an expert on the geology of the Canary Islands and tells Gaia Vince that eruptions are regular events on the islands. There's been much discussion about where we are going to get our energy from in the UK. Gas prices are soaring, a fire has knocked out a key power cable, and the weather has affecte...

Sep 23, 202132 min

Perseverance drills on Mars; space tourism; Australian fire debris and algal blooms; DNA vaccines against Covid

NASA's Perseverance rover has been trundling around the Jezero crater since it landed successfully in February 2021. A few weeks ago it made its first attempt at collecting a sample of rock. Unfortunately the rock turned out to be so crumbly it disintegrated away. But Perseverance lives up to its name and has been drilling elsewhere and has now collected two samples. The rover has stored them in special canisters for later collection. Katie Stack-Morgan, Deputy Project Scientist of the Mars 2020...

Sep 16, 202131 min

Climate change and oil and gas exploration; cutting methane emissions; African wild dog populations; freezing eggs and sperm

We’re just weeks away from the big international climate talks in Glasgow, where governments will be trying to figure out a workable plan for how to keep global temperature rise below 1.5 degrees. Gaia Vince explores a couple of strategies to tackle climate change. By far the biggest source of the rise comes from the release of greenhouse gases when we burn fossil fuels, like coal, oil and gas. So it’s no surprise that we need to cut back on this habit - but much of the discussions are over how ...

Sep 09, 202129 min

Rugby and the brain

Victoria Gill talks to Professor Damian Bailey who's leading research at the University of South Wales into the potential risks to brain health in contact sports players, from impacts to the head and body sustained during play. His latest study found that over the course of a 31 game season, the brains of members of a professional rugby union team underwent measurable changes, particularly the forward players who sustained most tackles, knocks and falls. The findings may help to identify why pro...

Sep 02, 202129 min

Window to solve pandemic origins closing

Virologist Marion Koopmans is one of the independent researchers appointed by the World Health Organisation to investigate the origins of the coronavirus pandemic. The team visited China in January this year as a first step to answer how, when and where SARS-Cov-2 first infected humans. Professor Koopmans tells Victoria Gill that time is beginning to run out to launch the next phase of studies, to trace the first people in China to be exposed and identify the animals from which the virus jumped ...

Aug 26, 202129 min

Mammoth Journey

A 17,000 year old tusk contains a remarkable story of the lifetime travels of a woolly mammoth which roamed the grasslands of Ice Age Alaska. The animal travelled 70,000 kilometres over the course of three decades before his premature death north of the Arctic Circle. The University of Alaska's Matthew Wooller tells Victoria Gill how his team pieced together the mammoth's life from isotopic clues captured in the tusk. Also in the programme: The search for storage capacity underground for all the...

Aug 19, 202130 min

IPCC report - extreme weather events

Victoria Gill talks to climate scientist Friedericke Otto about the Intergovernmental Panel on Climate Change's new landmark report. The report this week states that the evidence for humanity's role in changing global change is now unequivocal. Dr Otto was a lead author on the chapter on extreme weather events and explains how human influence can be attributed to the increasing incidence and intensity of heat waves and heavy rainfall events. Also in the programme: Immunological evidence to suppo...

Aug 12, 202130 min

Bees and multiple pesticide exposure

Victoria Gill looks at the latest stories from the world of science. In this week's episode: the threat to bees from multiple pesticide exposure, how bee colonies can evolve defences against the varroa parasite, more problems for the Starliner space capsule, and what may be the oldest fossil animals yet found.

Aug 05, 202132 min

Covid 19 – reaching the unvaccinated

In the UK we have seen a recent fall in Covid 19 cases. Good news, but we don’t know yet if this will be sustained. The virus is now thought to be spreading predominantly amongst the under 30s, most of whom remain unvaccinated. Young adults are the demographic most likely to be vaccine hesitant or vaccine averse. Kavita Vedhara from Nottingham University discusses the delicate balancing act of managing personal choice and collective responsibility needed to persuade people to get vaccinated to h...

Jul 29, 202130 min

A life-changing database

Proteomes, the sequences of protein within the DNA of every living thing, are notoriously difficult to model. The usual chemical methods can take months, but a new computational model using the ability of artificial intelligence to learn the complex sequences is able to predict structures within a matter of hours. Thousands of protein structure predictions are now available on a public database for anyone to access. Understanding such proteins is seen as key to treating nearly all disease. It al...

Jul 22, 202133 min

Covid19 - should we test everybody ?

Epidemiologist Julian Peto is advocating mass testing as the key part of a plan to stop the virus spreading. Studies where everyone has been tested have picked up asymptomatic cases. With the addition of isolation and contact tracing this method of testing has been able to massively reduce the spread of the virus. The hope is such a coordinated scheme implemented nationally could help bring the numbers down. There’s a question over which type of test is best to use for mass testing. At the momen...

Jul 15, 202128 min

Covid and our ancient ancestors

A global project looking at the genomes of over 2 million people has found a number of distinct genetic markers which seem to either make Covid infection more likely or the symptoms more severe. Some of these markers are known to be associated with susceptibility to cancer and lung disease. However the researchers say on their own these genetic factors are not determinants of how sick people will become. Underlying health, age and sex and a range of environmental and social factors are likely mo...

Jul 08, 202128 min

Gene editing gets real

For the first time the gene editing technique CRISPR has been used by injecting the CRISPR instructions into the bloodstream rather than directly into the affected organ. In a trial, six adult patients showed improvements after the treatment was used to prevent the expression of deformed proteins associated with a genetic disease. The hope is this method could treat a range of other genetic diseases, says Megan Molteni from Stat News. In the near future domestic gas boilers may be replaced by he...

Jul 01, 202132 min

UK science policy shake-up; Ivermectin & Covid; black fungus in Indian Covid patients; many hominins in Siberian cave

The Prime Minister has announced his desire for the UK to become a 'science superpower'. A new office within the cabinet to look at science will work alongside existing science strategy and funding structures. So far it's unclear where the responsibilities between the various science policy bodies lie. James Wilsdon, Professor of Research Policy at the University of Sheffield, helps Gaia Vince pick her way through the spaghetti of overlapping organisations and Dame Ottoline Leyser, UKRI Chief Ex...

Jun 24, 202134 min

Cov-Boost trial; SARS-Cov 2 infection in action; sapling guards; why tadpoles are dying

Scientists are now looking at the question of third doses of vaccines against SARS-Cov2, and this week the Cov-Boost trial was launched. It’s being run from University of Southampton and is going to be using seven different vaccines, some at half doses, in people over the age of 30 who were early recipients of their two doses. The Chief Investigator, immunologist Professor Saul Faust explains the aims of the trial. Once we've breathed the coronavirus into our lungs, how does it spread through ou...

Jun 17, 202130 min

Covid vaccines in children; preventing dengue; algal blooms; supersonic flight

Should we be vaccinating children in the UK against SARS-Cov 2? Children are rarely seriously ill if they catch Covid but infections mean missed school, and they can pass it onto older vulnerable people. The US, Canada, Israel and Dubai are some places that are already vaccinating the under 18s and Pfizer has recently published data from a trial of its mRNA vaccine in just over 2000 12-15 year olds, showing no safety concerns. Gaia Vince discusses the issue with Professor Beate Kampmann, consult...

Jun 10, 202132 min

Lab origin theory of SARS-Cov2; gene for obesity; dark matter map; rock art in Scotland

Sars Cov2, as the Covid19 coronavirus is called, probably began as the vast majority of new diseases do, when an animal virus infected a person – perhaps in a market or farm. There’s a large animal market in the city of Wuhan that sold wild as well as farmed animals, and studies have shown that different species of animals can infect each other with coronaviruses on their journey to market. But there’s also a possibility that the virus originated in one of two government laboratories in Wuhan. A...

Jun 03, 202132 min

Human use of plants beyond the limits of history.

Human impact on planet earth’s plant life might be detectable several thousand years back in fossil pollen cores taken from mud columns around the world. As Suzette Flantua and Ondrej Mottl describe in a paper published in the journal Science, a rapid acceleration in the changes in pollen species goes back further than we might have expected. This matters particularly when it comes to decisions around re-wilding and re-planting areas today in the name of conservation. As they hope to build on in...

May 27, 202136 min

Blood Clot Cure, Synthetic Fuels and Coal Mine Heat Pumps

Vic Gill talks to scientists who have cured a vaccine-induced blood clot patient, and meets a former top F1 chief engineer who wants to transform the fuel industry. Scientists in Vienna have been continuing to look at the rare blood clots associated with the AZ Covid-19 vaccination. Paul Knoebl describes to Vic his paper describing the diagnosis and successful treatment of a patient who developed a fever whilst skiing six days after taking it. Whilst the side effect is still condsidered incredib...

May 20, 202143 min

Microplastics in UK river beds

Untreated wastewater "routinely released into UK rivers" is creating microplastic hotspots on riverbeds. That is the conclusion of a study in Greater Manchester, which revealed high concentrations of plastic immediately downstream of treatment works. The team behind the research concluded: untreated wastewater was the key source of river microplastic. Jamie Woodward takes Vic Gill wading in the River Tame in Greater Manchester to show some of the sites they studied, while co-author Rachel Hurley...

May 13, 202136 min

Early burials, diversity in Tudor England, a malaria vaccine, and rogue brain waves

Despite being home to our early ancestors, attempts to find evidence of early burials in Africa have proved unsuccessful. That is until now. Professor María Martinón-Torres explains how findings from a 78,000-year-old Kenyan grave shed light on how our ancestors related to the dead. In keeping with the theme of clues from the past, Cardiff University academics have been studying the remains of crew who drowned on King Henry VIII’s favourite ship, the Mary Rose. As it turns out, Tudor England was...

May 06, 202128 min
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