Heparin & the Anti-Xa Assay

Basics to Brilliance: Haematology Podcast

May 25, 2025•59 min•Season 2Ep. 5

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00:52 Intro (shoutuout to the BSH anticoagulant monitoring guidelines)

02:15 Practical relevance of testing and monitoring anticoagulants

07:30 Heparin: The Basics

09:00 Unfractionated Heparin vs. Low Molecular Weight Heparin

10:24 Mechanism of action of Heparin (UfH vs. LMWH)

LMWH: more Anti-Xa activity
UfH Anti-IIa acitivity = Anti-Xa activity

15:30 Pharmacokinetic differences (UfH vs. LMWH)

23:28 Unfractionated Heparin uses and monitoring

34:34 Anti Xa Assay

42:32 Activated Clotting Time (POCT)

46:56 Anti Xa in LMWH: Practical considerations

52:03 LMWH uses and dosing

55:30 Summary

'Basics to Brilliance: Haematology Podcast' has been accredited for CPD credit by the Royal College of Pathologists UK.

Medical professionals and clinical scientists holding career-grade positions, who are registered with any of the Royal Colleges for CPD, will be eligible to earn 1 credit for every hour of learning.

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