Membrane Biochemistry XXX. Nociception as component of Subcortical-Limbic Involvement of the Conditioned Fear Response in Mammals. DJGPhD. 8Aug22. Authentic Biochemistry
References Dr Guerra's Neuroscience lecture notes
Aug 09, 2022•30 min
Authentic Biochemistry
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Episodes
Membrane Biochemistry XXIX. Final discussions on serum albumin and membrane disruption mediated inflammatory modulation. Dr. Daniel J. Guerra. 7bAug22.Authentic Biochemistry.
References Dr Guerra's lipid lectures Int J Mol Sci. 2019 Oct; 20(19): 4860 JNCVolume109, Issue3May 2009 Pages 694-705
Aug 07, 2022•30 min
Membrane Biochemistry XXVIII. Serum Albumin as an arbiter of neuronal inflammation or peripheral removal of circulating endogenous Danger/Damage-Associated Molecular Patterns. 7Aug22. DJGPhD.
References Dr Guerra's lecture notes J.of Neuroinflammation. 2016. volume 13, Article number: 264 Am J Med. 2020 Jun;133(6):713-722.e7. J Hepatol. 2014 Aug;61(2):396-407.
Aug 07, 2022•30 min
Membrane Biochemistry XXVII. Traumatic Brain Injury and Ischaemic Stroke associated neuroinflammation is mediated through membrane caveolae. Dr Daniel J. Guerra.3Aug22. Authentic Biochemistry.
References Dr. Guerra's: membrane lectures J Clin Med. 2021 Sep; 10(17): 3795 J Neuroinflammation. 2016; 13: 264.
Aug 04, 2022•30 min
Membrane Biochemistry XXVI. Lipid molecular structures and membrane morphology impacting biological activity. Dr Daniel J. Guerra. 01August2022. Authentic Biochemistry Podcast Productions.
References Dr Guerra's lipid lecture archive
Aug 02, 2022•30 min
Membrane Biochemistry XXV. From Plotinus through Kant to Membrane lipids: an a priori synthesis of research scientific event concepts. DJGPhD.Authentic Biochemistry.31.7.22
References Dr. Guerra's notes Ennead V-Plotinus Critique of pure Reason-Kant Biophysical Journal.2009. 96(7):2676-88).
Jul 31, 2022•1 hr
Membrane Biochemistry XXIV. Legionella- assocated TLR mediated LPS containing sialic acid interactions and the Caveolar Involvement in Pathobiochemistry.DJGPhD. 29.7.22.Authentic Biochemistry.
References Dr. Guerra's notes Front. Immunol., 26 August 2020 Int. J. Mol. Sci. 2021, 22, 1487
Jul 30, 2022•30 min
Membrane Biochemistry XXIII. DNA recombination and methylation associated autoimmune and cancer pathology via TLR4 and membrane lipid rafts. DJGPhD.28.7.22. Authentic Biochemistry
References Dr Guerra's notes Oncotarget. 2016 Jan 26; 7(4): 4195–4209 FEBS J. 2017 Jun; 284(11): 1590–1605 Biochim Biophys Acta Mol Basis Dis. 2021 Oct 1;1867(10):166184. Biol. Cell (2007)99, 129–140
Jul 28, 2022•30 min
Membrane Biochemistry XXII*. The dialectical event ontology of caveolae-associated disease is florid with no absolute relational, quantitative, qualitative or modal conformity.DJGPhD.27.7.22
References The first reference is my preceding video podcast lecture Membrane Biochemistry XXI published on youtube *https://youtu.be/ZEEYOganuCU Dr Guerra's notes J Immunol August 1, 2017, 199 (3) 874-884 Ann Rev Cell Devel.Biology 2018. 34:111-136 Blood . 2016 Apr 14;127():1930-9
Jul 28, 2022•30 min
Membrane Biochemistry XX. Loss of CNS CA1-Caveolae Formation in Obese Type-2 Diabetics is Linked to insulin Resistance and Alzheimer's Disease. DJGPhD24.7.22. Authentic Biochemistry.
References Archivum Immunologiae et Therapiae Experimentalis 2013 Apr;61(2):119-25. Journal of Neuroscience 23 October 2019, 39 (43) 8576-8583 Annual Review of Cell and Developmental Biology 2018 Volume 34, pp 111-136
Jul 24, 2022•26 min
Membrane Biochemistry XIX. Oxysterols and LDLR in atherosclerosis: transcriptional mediation of membrane control over cholesterol homeostasis. 21.7.22. DJGPhD.Authentic Biochemistry
References Dr Guerra's lipids lectures Nature 2008. volume 455, pages40–41. Nature Immunology 2013. volume 14, pages893–900 European Heart Journal 2021. Vol 12 Dec.
Jul 21, 2022•30 min
Membrane Biochemistry XVIII> Valproic acid and Platelt Activating Factor:Membrane lipids in Alzheimer's DiseaseDJGPhD 18.7.22 Authentic Biochemistry
References Dr Guerra's lipid lecture notes European Medicines Agency•20/05/2022 Pharmaceuticals (Basel). 2022 Feb; 15(2): 192 Neuropharmacology Volume 128 , January 2018, Pages 54-62
Jul 19, 2022•30 min
Membrane Biochemistry XVII. Epoigenetic changes in protein controlled membrane lipid transport in human disease. DJGPhD.14.7.22
References Dr Guerra's notes Biomedicines. 2021 Dec; 9(12): 1908 RNA. 2020 Aug; 26(8): 903–909 Journal of Alzheimer's Disease, 1 Jan. 2019 : 743 – 750.
Jul 15, 2022•30 min
Membrane Biochemistry XVI. The Acid Sphingomyelinase Deficiencies. Dr Dan Guerra. 13.7.22 Authentic Biochemistry
References Dr. Guerra's notes Biochem Biophys Res Commun. 2007 Aug 31;360(3):593-9 Cell Death Dis. 2021 Feb; 12(2): 180.
Jul 13, 2022•30 min
Membrane Biochemistry XV. REST mediated gene repression and membrane function and plaque formation in atherosclerosis. DJGPhD. 11JUly22. Authentic Biochemistry
References Pharmacology & Therapeutics Available online 27 June 2022, paper # 108237 Cell Death Dis. 2021 Feb; 12(2): 180. Dr Guerra's notes
Jul 12, 2022•1 hr
Membrane Biochemistry XIV. Apoptosis and Necroptosis review. Dr. Daniel J. Guerra. 8 July 2022. Authentic Biochemistry Podcast
References Dr Guerra's notes Oncogene. 2009 Sep 3;28(35):3097-110 Mol Cell Biol. 2005 Aug;25(15):6363-79 J Neuroinflammation. 2019; 16: 236.
Jul 09, 2022•26 min
Membrane Biochemistry XIII.Fatty acid induced membrane protein phosphorylation can shift pro-oncogenic to apoptotic cell fate in human breast cancer cell lines. DJGPhD. 5July 2022 Authentic Biochem.
References Dr. Guerra's notes The Journal of Nutrition, Volume 137, Issue 3, March 2007, Pages 548–553
Jul 05, 2022•30 min
Membrane Biochemistry XII. The specificity of membrane lipid raft molecular species and the dialectics of protein sorting. DJGPhD.3 July 2022 Authentic Biochemistry.
References Dr. Guerra's notes The Journal of Nutrition, Volume 137, Issue 3, March 2007, Pages 548–553 Front Immunol. 2019; 10: 1309. Int J Mol Sci. 2019 Oct 11;20(20):5028
Jul 04, 2022•30 min
Membrane Biochemistry XI. Inflammasomes and omega three fatty acid involvement in various pathogenic and human disease states. DJGPhD.02.July 2022.
References Front Immunol. 2019; 10: 1309. Int J Mol Sci. 2019 Oct 11;20(20):5028.
Jul 02, 2022•30 min
Membrane Biochemistry X. Dialectical Event Ontologies and the Complexity of Biological Systems. Dr. Daniel; J.Guerra 2 July 2022 Authentic Biochemistry
References Dr Guerra's ideas
Jul 02, 2022•30 min
Membrane Biochemistry IX. Omega Three fatty acid utilization via oxygenation to control inflammation. DJGPhD. 30.6.22 Authentic Biochemistry Podcast production
References Dr Guerra's notes Int J Mol Sci. 2019 Oct 11;20(20):5028
Jul 01, 2022•30 min
Membrane Biochemistry VIII. The basics of lipid membranes. Part 1. Dr Daniel J. Guerra. Authentic Biochemistry Podacst Production. 28.6.22
References Dr Guerra's lectures PNAS September 28, 2010 107 (39) 16783-16787;
Jun 29, 2022•30 min
Membrane Biochemistry VII. DNA methylation and histone acetylation may be at the core of memory and learning via LTP associated Integral Membrane Excitation. DJGPhD.24.6.22 Authentic Biochemistry.
References Sci Signal. 2016 Aug 23; 9(442): ra83. Dr Guerra's Neuroscience lectures
Jun 25, 2022•30 min
Membrane Biochemistry VI. The involvement of membrane lipid omega 3 fatty acids in LTP and memory acquisition. Part 1. Dr Guerra. 23.6.22. Authentic Biochemistry
References Dr Guerra lecture notes Nature Communications volume 11, Article number: 6133 (2020) Current Biology Volume 31, Issue 11, 7 June 2021, Pages 2274-2285.e5 Eur J Neurosci. 2019 Jan;49(1):40-50
Jun 24, 2022•30 min
Membrane Biochemistry V. Epigenetic alteration of gene expression is predicated by free will induced synaptic plasticity as an event ontology. DJGPhD. 21.6.22 Authentic Biochemistry
References Dr Guerra's notes,concepts and ideas Sci Signal. 2016 Aug 23; 9(442): ra83.
Jun 21, 2022•30 min
Membrane Biochemistry IV. Synaptic Plasticity and Oncological Phenomena involving DNA Methylation. Dr. Daniel J. Guerra. 20.6.22 Authentic Biochemistry
References Dr Guerra's notes Sci Signal. 2016 Aug 23; 9(442): ra83 Front. Pharmacol., 24 April 2019
Jun 21, 2022•30 min
CytoEpigenetics XIX. Some examples of epigenetic methylation and acetylation patterns in disease and the concept of maintenance methylation. Dr Daniel J. Guerra. 06June2022
References Dr Guerra's notes Arteriosclerosis, Thrombosis, and Vascular Biology. 2005;25:436 JAMA. 2008;299(11):1345-1350
Jun 06, 2022•30 min
CytoEpigenetics XVIII. Membrane lipid architectonics organized for cell cycle and both nuclear and mitochondrial biochemical mediation of gene expression. Dr. Dan Guerra. 05 June 2022
References Dr Guerra's synthesis of lecture material Histochemistry and Cell Biology volume 145, pages275–286 (2016) Biol Rev Camb PhilosSoc.. 2018 May;93(2):827-844.
Jun 05, 2022•20 min
CytoEpigenetics XVII. The role of ceramide metabolism in epigenetic and bioenergetic cross talk among multiple subcellular compartments. Dr Dan Guerra. 03June2022 Authentic Biochemistry Podcast
References Dr Guerra's synthesis of lectures Scientific Reports volume 5, Article number: 15292 (2015)
Jun 04, 2022•30 min
CytoEpigenetics XVI. The Mt DNA replicase and helicase enzymes are epigenetically nuclear encoded and localize to the mitochondrial membrane into lipid rafts containing cholesterol. DJGPhD. 2June2022
References Dr Guerra's lecture sytheses Scientific Reports volume 5, Article number: 15292 (2015)
Jun 02, 2022•30 min
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