Dhineli Perera talks to pharmacists Amy Legg and Tony Lai about their paper on the safe and effective use of vancomycin. They discuss the evolution of vancomycin therapeutic drug monitoring, including trough concentrations, and demystify AUC monitoring. They cover current recommendations, including targets for drug efficacy and safety, and priority patient groups. Read the full article by Amy, Tony, and their co-authors, in Australian Prescriber ....
Jun 16, 2025•24 min•Ep. 190
Justin Coleman speaks with Alice Poulton, genetic counsellor, about noninvasive prenatal testing (NIPT) to screen for aneuploidies such as trisomy 21 (Down syndrome). Alice explains how NIPT differs from serum screening and ultrasound options, and when each option may be used. The conversation also covers advice on interpreting the NIPT results and when invasive testing may be offered. Read the full paper in Australian Prescriber....
May 26, 2025•15 min•Ep. 189
David Liew talks to Linny Phuong, paediatric infectious diseases physician, about changes to prevention and management of respiratory syncytial virus (RSV). They discuss how RSV infections affect communities in Australia, high-risk groups to watch out for, and when to test for RSV. Linny also outlines available RSV immunisations for different populations. Read the full article by Linny and her co-author, David Foley, in Australian Prescriber ....
May 12, 2025•16 min•Ep. 188
Dhineli Perera chats with Allen Cheng, director of Infectious Diseases at Monash Health and member of the Antibiotic Expert Group, about some of the updates in the latest version of Therapeutic Guidelines: Antibiotic. Allen talks about changes to severity assessment and treatment for community-acquired pneumonia, updated antimicrobial dosing advice, a new tiered approach for managing patients with sepsis and much more.
May 05, 2025•24 min•Ep. 187
Jo Cheah talks to Bronwyn Jenkins, consultant neurologist, about the role of calcitonin gene-related peptide (CGRP)–targeted therapies in migraine treatment. Bronwyn explains the difference between tension-type headaches and migraines, and outlines current treatment options. The conversation also covers adverse effects, patient eligibility, and other important considerations for prescribers. Read the full article in Australian Prescriber ....
Apr 21, 2025•23 min•Ep. 186
Justin Coleman speaks with Kate Ziser, a pharmacist at the Princess Alexandra Hospital in Brisbane, about her paper on the role of triple antithrombotic therapy in patients with atrial fibrillation following coronary stent insertion. Kate explains when triple therapy is indicated, the duration of therapy, and the step-down approach to antithrombotic therapy. Read the full article by Kate and her co-authors in Australian Prescriber ....
Mar 31, 2025•13 min•Ep. 185
Laura Beaton chats with Nadia Mouchaileh, senior pharmacist, and Jillian Cameron, head of movement disorders and consultant neurologist at Austin Health, about device-assisted therapies for Parkinson disease. They discuss the benefits vs traditional therapies, when to refer patients to a specialised movement disorder centre and what to look for when caring for a patient using a device. Read the full article in Australian Prescriber ....
Mar 17, 2025•21 min•Ep. 184
Jo Cheah talks to Debra Kennedy, director of MotherSafe, about her paper on drug safety in pregnancy. Debra discusses the key considerations when stopping or starting a medicine during pregnancy, and the ways in which medicines can affect developing fetuses. Debra also explains the Australian categorisation system for prescribing medicines in pregnancy. Read the full article by Debra and her co-author, Ronald Batagol, in Australian Prescriber ....
Mar 03, 2025•20 min•Ep. 183
Dhineli Perera speaks with Lee Fong, a medical advisor for the Australian Commission on Safety and Quality in Health Care, about the need to establish a national clinical care standard for people with chronic obstructive pulmonary disease (COPD). Lee explains how the Standard can be used to identify gaps in care and optimise the management of patients with COPD. Read the full article by Lee and his co-authors in Australian Prescriber ....
Feb 24, 2025•19 min•Ep. 182
David Liew talks to Claire Larter, a medical officer at the pharmacovigilance branch of the TGA, about her paper on adverse event reporting. Claire explains why pharmacovigilance is important for clinicians, and outlines what type of adverse events should be reported. The conversation also covers the process of reporting adverse events and how the TGA handles reports. Read the full article by Claire and her co-authors in Australian Prescriber ....
Feb 10, 2025•18 min•Ep. 181
Laura Beaton chats with Paul Kubler, director of Rheumatology at Royal Brisbane and Women’s hospital, about how to identify and manage antiphospholipid syndrome. They discuss the key presentations of APS, classification criteria and approaches to treatment. They also cover patients with catastrophic APS and asymptomatic people with persistent antiphospholipid antibodies. Read the full article by Paul and his co-authors in Australian Prescriber....
Jan 20, 2025•16 min•Ep. 180
Jo Cheah talks with Eileen Cole, GP lead, and Jennifer Kyi, pharmacist advisor at Quit, about the use of therapeutic vapes for smoking cessation. They discuss the current evidence and new Australian guidelines. The conversation also covers choosing a vape and how to prescribe or supply vapes. Read the full article by Eileen, Jennifer, and their co-authors, in Australian Prescriber ....
Jan 06, 2025•18 min•Ep. 179
In this episode Dhineli Perera speaks to John Turnidge, who leads the national surveillance program for Antimicrobial Use and Resistance in Australia. They discuss the significant impact of the pandemic on reducing antibiotic use in the community, and how this benefit can be sustained and improved on. Read the full article by John and his co-authors, Carolyn Hullick and Kim Stewart, in Australian Prescriber ....
Dec 09, 2024•18 min•Ep. 178
Laura Beaton chats with Debbie Rigby, from the National Asthma Council, about her paper on inhaler device selection for people with asthma or chronic obstructive pulmonary disease. Debbie outlines the different types of inhalers available, and explains their benefits, limitations and environmental considerations. They also discuss ensuring patients are using their inhalers effectively. Read the full article by Debbie in Australian Prescriber ....
Nov 25, 2024•18 min•Ep. 177
Jo Cheah talks to Tom Simpson, President, and Jerry Yik, Head of Policy and Advocacy, at Advanced Pharmacy Australia. They discuss the ongoing challenge of medicine shortages in Australia, and advise on how to identify, communicate and manage shortages using available resources. Read the full article by Tom and Jerry in Australian Prescriber .
Nov 11, 2024•18 min•Ep. 176
Laura Beaton chats with endocrinologist Jillian Tay about her article on the pharmacological management of polycystic ovary syndrome (PCOS). They discuss the 2023 international PCOS guideline, including updates to the diagnostic criteria, and different pharmacological treatments to manage symptoms of PCOS. Read the full article by Jillian and her co-author, Carolyn Ee, in Australian Prescriber ....
Oct 28, 2024•16 min•Ep. 175
Dhineli Perera talks to complex care coordinator Deirdre Criddle and senior pharmacist Rohan Elliott about their paper on safe medication management during transitions of care from hospital. They cover the potential hazards that arise during transitions of care, available services, and the need for a stewardship framework for managing hospital transitions. Read the full paper by Deirdre, Rohan, and their co-authors, in Australian Prescriber ....
Oct 14, 2024•22 min•Ep. 174
Laura Beaton sits down with infectious diseases physician Anna Pierce to discuss her article on the management of occupational exposure to blood and body fluids in primary care. Anna explains the importance of prevention measures, the steps to take after an exposure, as well as the principles of management for exposure to hepatitis B, hepatitis C and HIV. Read the full article in Australian Prescriber ....
Sep 30, 2024•19 min•Ep. 173
David Liew talks to rheumatologist Nicola Cook about the utility of common investigations for suspected inflammatory arthritis in adults. They discuss the notion of pretest probability and how this is used to determine the utility of testing, and the role of specific tests. Nicola also talks about the potential harm of overinvestigation. Read the full article by Nicola and her co-author, Rachelle Buchbinder, in Australian Prescriber ....
Sep 16, 2024•20 min•Ep. 172
Dhineli Perera chats with infectious diseases physician Emily Tucker about her article on controversies in the management of community-acquired pneumonia (CAP) in adults. Laura talks about severity scoring tools, organisms involved with CAP, and the antibiotics and other treatments used to manage CAP. Read the full article by Emily and her co-authors in Australian Prescriber ....
Sep 02, 2024•19 min•Ep. 171
Dhineli Perera talks to Jonathan Dartnell, managing director of QUM Connect, and Darlene Cox, Executive Director of Health Care Consumers’ Association, about changes to the quality use of medicines landscape. They discuss the challenges and opportunities following the closure of NPS MedicineWise and speculate on the future of QUM in Australia. Read the full article by Jonathan, Darlene, and their co-authors, in Australian Prescriber . This interview was conducted on 3 July 2024....
Aug 26, 2024•17 min•Ep. 170
Laura Beaton talks to pharmacist Aili Langford and geriatrician Sarah Hilmer about their article on deprescribing antihypertensive drugs in frail older adults. They discuss how the potential benefits and harms of lowering blood pressure may change with increasing age and frailty, the evidence for deprescribing, and how to deprescribe antihypertensive drugs. Read the full article by Aili, Sarah, and their co-authors, in Australian Prescriber ....
Aug 05, 2024•21 min•Ep. 169
David Liew speaks with geriatrician and dementia specialist Louise Waite about her article on new and emerging therapies for Alzheimer disease. Louise explains key biomarkers for Alzheimer disease, and the potentially disease-modifying monoclonal antibody therapies that have been approved by the FDA and are now being considered by the TGA in Australia. Read the full article by Louise in Australian Prescriber ....
Jul 22, 2024•19 min
Justin Coleman talks to Darren Mansfield, Director of the Epworth Sleep Centre, about his article on the diagnosis and management of obstructive sleep apnoea (OSA) in adults. Darren outlines high-risk populations for OSA and the importance of screening. He also covers treatments, including CPAP therapy, positional and oral appliances, and surgical options. Read the full article by Darren and his co-author, Daniel Hynes, in Australian Prescriber ....
Jul 08, 2024•20 min•Ep. 167
Jo Cheah speaks to Peter Wark about his article on biologic therapies for severe asthma with persistent type 2 inflammation. Peter explains the difference between difficult and severe asthma and how to test for persistent type 2 inflammation. He also runs through the available biologics and when and how they are used. Read the full article by Peter and his co-author, Sahan Chandrasekara, in Australian Prescriber....
Jun 24, 2024•16 min•Ep. 166
Justin Coleman talks to Garry Jennings, Chief Medical Advisor of the National Heart Foundation of Australia, about his article on the 2023 Australian Guideline for Assessing and Managing Cardiovascular Disease Risk. Garry discusses the updates to the guideline, including the age from which assessment should occur and new risk factors considered, and he gives some tips for communicating cardiovascular disease risk to patients. Read the full article by Garry and his co-authors in Australian Prescr...
Jun 10, 2024•16 min•Ep. 165
David Liew talks to gastroenterologist Varan Perananthan about his article on diagnosis and management of eosinophilic oesophagitis (EoE). Varan explains the causes and symptoms of EoE, why the prevalence has been increasing, and how to differentiate EoE from gastro-oesophageal reflux disease. Also discussed are dietary approaches for identifying food triggers and pharmacological treatments for EoE. Read the full article by Varan and his co-author, Rebecca Burgell, in Australian Prescriber ....
May 27, 2024•17 min•Ep. 164
Laura Beaton talks to Leonie Callaway, Obstetric and General Physician and Director of Research at the Royal Brisbane and Women’s Hospital, about her article on the management of pre-existing diabetes in pregnancy. Leonie talks about maternal and fetal complications and the importance of high-quality preconception care, factors that can affect glucose control and the benefits of continuous glucose monitoring, and postpartum care. Read the full article by Leonie and her co-author Fiona Britten in...
May 13, 2024•19 min•Ep. 163
Laura Beaton speaks to Karen Magraith, GP and immediate-past president of the Australasian Menopause Society, about treatments for menopausal symptoms. They discuss the benefits of menopausal hormone therapy (MHT) and how to choose the most suitable preparation, as well as duration of therapy and nonhormonal treatment options for those with contraindications to MHT. Read the full article by Karen and her co-author, Christina Jang, in Australian Prescriber....
Apr 29, 2024•15 min•Ep. 162
Dhineli Perera sits down with Adam Nelson to discuss updates in the management of hypercholesterolaemia. Adam explains how triglycerides, LDL cholesterol and HDL cholesterol differ in their links to cardiovascular disease. He provides useful tips for checking a lipid profile and highlights other tests that may be helpful when assessing a patient with hypercholesterolaemia. Adam also explains the latest in treatments for reducing LDL cholesterol concentrations and what this means for the role of ...
Apr 08, 2024•22 min•Ep. 161
