Sounak Gupta, M.B.B.S., Ph.D., explains how Mayo Clinic Laboratories' gynecological NGS panels provide focused assessments of gynecological cancers. The cost-effective tests fill the gap between single gene assays and large cancer panels, to inform prognosis and treatment. (00:32) Could you provide our listeners with a little bit about yourself and your background, please? (01:22) Could you give a brief overview of the new assays? (03:55) Can you talk a little about both the ovarian and gynecolo...
Jul 18, 2023•12 min•Ep. 240
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to discuss locally acquired cases of malaria that have recently occurred in Texas and Florida. Their discussion includes: Why malaria may be reappearing after being eliminated in the United States in the 1950s. The importance of laboratory diagnostics in identifyi...
Jul 13, 2023•9 min•Ep. 239
Sounak Gupta, M.B.B.S., Ph.D., explains how Mayo Clinic Laboratories' urologic panels efficiently inform prognosis and individualized cancer treatment. The carefully curated panels fill the void between single gene assays and large NGS panels. (00:32) Could you provide our listeners with a little bit about yourself and your background, please? (01:35) Could you give us a brief overview of the newly developed urologic assays? (03:51) Can you talk a little bit more about what patients should have ...
Jul 11, 2023•18 min•Ep. 238
The Centers for Disease Control and Prevention (CDC) issued a recent health advisory to remind healthcare providers to be on the lookout for cases of measles and to educate patients on measles prevention. In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by Matthew Binnicker, Ph.D., director of the Clinical Virology Laboratory at Mayo Clinic, to discuss why measles prevention continues to be c...
Jul 06, 2023•14 min•Ep. 237
John Lieske, M.D., explains why it's now easier for clinicians to pull information from Mayo Clinic Laboratories' urine supersaturation test report. An updated format summarizes complex information to help guide the treatment of kidney stones. (00:32) Could you tell us a little bit about yourself and your background? (01:28) Could you give us a brief overview of urine supersaturation testing? How should it be used? How can it benefit providers and their patients? (04:14) Can you tell us a little...
Jul 04, 2023•11 min•Ep. 236
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to discuss the latest update on the U.S. Food and Drug Administration’s (FDA) proposed rule to oversee laboratory-developed tests (LDTs) and what that could mean for laboratories. Specific topics of discussion include: The FDA’s recent announcement on a proposed r...
Jun 29, 2023•9 min•Ep. 235
Angela Pickart, M.S., CGC, and Emily Lauer, M.S., CGC, explain how Mayo Clinic Laboratories' multigene panel helps identify the cause of hereditary ataxia. Precise diagnosis of this complex movement disorder helps guide patient treatment and family screening. Show notes Speaker 3: (00:31) Can you tell us a little about yourselves and your backgrounds? Speaker 3: (01:33) Why is genetic counseling so important to our doctors and patients? Speaker 3: (03:04) Can you give a brief overview of heredit...
Jun 27, 2023•13 min•Ep. 234
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to talk about the evolution of remote diagnostics and how Mayo Clinic’s remote cardiovascular monitoring services empower physicians and patients. Specific topics of discussion include: How a comprehensive diagnostics ecosystem includes patient data beyond traditi...
Jun 22, 2023•10 min•Ep. 233
Anne Tebo, Ph.D., explains how Mayo Clinic Laboratories' updated ALDG2 assay helps with the evaluation of patients with suspected autoimmune liver disease. The panel also helps with the evaluation of liver disease of unknown etiology. Speaker 2: (00:32) Could you provide a little bit about you and your background? Speaker 2: (02:05) Can you please give a brief overview of this assay? Speaker 2: (04:12) Which patients should have this testing and when should it be performed? Speaker 2: (07:17) Co...
Jun 20, 2023•16 min•Ep. 232
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to talk about the tick season peak that parts of the United States are experiencing, and how to diagnose and prevent Lyme disease. Specific topics of discussion include: What parts of the United States have a heavy tick and Lyme disease presence. How Mayo Clinic i...
Jun 15, 2023•12 min•Ep. 231
Research and discoveries in the biopharmaceutical industry drive health care innovation and lead to new therapies for patients. When laboratories collaborate with biopharma, diagnostic, and biotech companies, it creates an integrated diagnostic ecosystem that can improve global health. In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of May...
Jun 08, 2023•16 min•Ep. 230
Artificial intelligence (AI) can be an excellent tool for enhancing patient care and streamlining efficiencies in the lab. But because of its potential risks, AI must be thoughtfully and responsibly applied, both now and in the future. In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to talk about how AI is impa...
May 25, 2023•17 min•Ep. 229
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, and Elitza Theel, Ph.D., director of the Infectious Diseases Serology Laboratory at Mayo Clinic, talk about West Nile virus and why laboratories and the public need to be aware as mosquitoes reemerge. Specific topics of discussion include: Why the mosquito is the deadliest animal in the world. Symptoms, testing options, and prevention strategies for West...
May 18, 2023•17 min•Ep. 228
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to discuss broader changes that are unfolding in the national and global diagnostic industry, and what to expect in the coming years. Specific topics of discussion include: Reflecting on Dr. Morice’s recent participation in Executive War College and what’s on the ...
May 11, 2023•12 min•Ep. 227
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, and Elitza Theel, Ph.D., director of the Infectious Diseases Serology Laboratory at Mayo Clinic, discuss endemic fungal infections that can be found in North America, specifically blastomycosis and histoplasmosis. Specific topics of discussion include: The basics of Blastomyces and Histoplasma fungi, which can cause serious lung infections. The recent bl...
May 04, 2023•13 min•Ep. 226
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, and special guest Susan Van Meter, president of the American Clinical Laboratory Association (ACLA). In celebration of Medical Laboratory Professionals Week, they discuss the critical role laboratories play in patient care and key legislative issues that impact th...
Apr 27, 2023•24 min•Ep. 225
Sean Pittock, M.D., explains how Mayo Clinic Laboratories' novel Ma2 test aids diagnosis of autoimmune neurology disorders that are often caused by underlying cancer. Rapid diagnosis is key to preventing significant disability and disease. (00:31) Can you provide our listeners with a little bit of background on your role at Mayo Clinic? (01:56) Is Ma2 an example of identifying a need in patient care and then creating a test to fill that gap? (02:30) Can you give us an overview of the disease sta...
Apr 25, 2023•20 min•Ep. 224
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, and Nancy Wengenack, Ph.D., director of the Mycology and Mycobacteriology Laboratories at Mayo Clinic, discuss the increased focus on fungi and why emerging fungal infections can be concerning for health care facilities. Specific topics of discussion include: How fungi work inside and outside of the body. If it’s possible for fungal infections to turn an...
Apr 20, 2023•15 min•Ep. 223
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, and William Morice II, M.D., Ph.D., president and CEO of Mayo Clinic Laboratories, discuss how representation and advocacy make a difference in regulatory outcomes. Specific topics of discussion include: Why pathologists should be leading conversations about the future of health care. Advocating for issues facing the diagnostics industry, including reimb...
Apr 13, 2023•13 min•Ep. 222
Rong He, M.D., explains how Mayo Clinic Laboratories' IDHQ test speeds therapeutic decision making for adults with acute myeloid leukemia, or AML. The standalone assay yields faster results than next generation sequencing. (00:32) Would you provide a brief background of yourself? (01:42) Could you give an overview of the IDHQ test? (02:25) Is there anything more you'd like to touch on about the droplet digital PCR approach and high sensitivity? (03:09) Why are IDH1 and IDH2 important in disease ...
Apr 11, 2023•9 min•Ep. 221
In this test-specific episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, and Bjorn Oskarsson, M.D., a neurologist at Mayo Clinic’s Florida campus, discuss how the neurofilament light chain test available through Mayo Clinic Laboratories helps physicians diagnose neurological disease and assess neuronal damage. Specific topics of discussion include: Benefits of the neurofilament light chain test that uses plasma ...
Apr 06, 2023•13 min•Ep. 220
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, and William Morice II, M.D., Ph.D., president and CEO of Mayo Clinic Laboratories, discuss the increasing rates of tick-borne diseases and how to test for and prevent them. They also discuss what to watch from a federal legislative standpoint now that Congress is back in session.
Mar 30, 2023•6 min•Ep. 219
Elitza Theel, Ph.D., explains how Mayo Clinic Laboratories' unique Histoplasma and Blastomyces test provides cost-effective evaluation for fungal infections that cause pulmonary illness. The assay reliably detects both Histoplasma and Blastomyces pathogens in a single test. (00:32) Will you please give us a brief introduction of yourself and your role at Mayo Clinic? (01:34) Can you tell us which specific group of patients this test would be best suited for, how a provider would determine a pati...
Mar 28, 2023•12 min•Ep. 218
Mar 23, 2023•14 min•Ep. 217
Zhiyv (Neal) Niu, Ph.D., and Rodolfo Savica, M.D., Ph.D., explain why Mayo Clinic Laboratories' gene panel is the most comprehensive test available for inherited Parkinson's disease. The new panel covers all mutations known to cause the condition — or increase the risk of developing it. (01:37) Can you give us a brief overview of the inherited Parkinson's disease gene panel, and when it would be used, Dr. Niu? (02:31) Dr. Savica, can you give us a brief overview of the inherited Parkinson's dise...
Mar 21, 2023•11 min•Ep. 216
(00:31) Dr. Niu, could you provide us with a little bit of your background? (01:03) Dr. Klein, could you provide us with a little bit of your background? (01:40) Would you give us a brief overview of the new panel? (02:49) Dr. Klein, could you give us a simple background of what you see going on in this space? (03:33) Which patients should have this testing, and when should it be performed? (04:49) Are there alternatives available, and how do they compare with this new MUPAN panel? (05:51) How a...
Mar 14, 2023•9 min•Ep. 215
Many laboratorians are not patient-facing. So, while laboratories are critical to patient care, they may lack visibility when it comes to policymaking. In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, and William Morice II, M.D., Ph.D., president and CEO of Mayo Clinic Laboratories, discuss their leadership roles in national advocacy organizations and the importance of laboratorian engagement in the fe...
Mar 09, 2023•14 min•Ep. 214
(00:31) Would each of you share a little bit about yourselves and your backgrounds? (01:47) Could you provide us with an overview of what the WGSDX test is? (02:26) How is that different from other genetic tests, like exome or microarray? (03:56) Tell us more about who benefits from these tests. (07:17) Is this test recommended by expert groups? (09:10) How do providers go about ordering this test, and what sample types are accepted? (11:12) What type of variants are detected by this test? (13:0...
Feb 28, 2023•18 min•Ep. 213
Feb 23, 2023•17 min•Ep. 212
(00:31) Could you provide a little bit about yourself and your background? (02:04) Could you provide an overview of the chromosomal microarray assay? (05:49) Why should the chromosomal microarray assay be used over other available assays, such as FISH? (08:56) Does the chromosomal microarray provide good benefits in terms of gain of 7 and loss of 10, and EGFR amplification? (12:03) What's the value of utilizing the test alongside a neuro-specific NGS panel, such as Mayo Clinic Laboratories' NONC...
Feb 21, 2023•24 min•Ep. 211
