Angel Invest Boston - podcast cover

Angel Invest Boston

In the Decade of Biotech when there will be myriad opportunities to invest in angel-scale biotech startups. After decades of angel investing, I am focusing on the life science side of my portfolio and invite other angels to do the same. Here's why: https://www.labcoatventures.com/why-we-are-focused-on-early-stage-biotech/ I’m Sal Daher, host of the Angel Invest Boston Podcast. After immigrating to Boston as a child and attending Belmont High School, I studied engineering at MIT and Stanford. Decades of work in international finance followed. During that time, I invested in a handful of ventures founded by friends and acquaintances. Now, I’m a member of Walnut Ventures and MIT Angels and spend most of my time as an angel investor. Startups in my portfolio include: SQZ Biotech, Gelesis, Akili Interactive, Vedanta Biosciences, FineTune Learning, Concrete Sensors, Squadle, doDoc, Pixability, Mavrck, Viral Gains, Streamroot, XMOS, Alice's Table and others. Exits include: Exos (Microsoft), Rifiniti (KKR) and PIKA Energy (Generac).
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Episodes

Raza Shaikh, Founder, Angel and Podcaster

Sponsored by Peter Fasse of Fish and Richardson, Top Patent Attorney: https://www.fr.com/team/j-peter-fasse/ A successful founder who has become a respected angel investor in Boston, Raza Shaikh is a pleasure to speak to and to learn from. Raza also has a podcast called On Boards which is great for people who are on boards or would like to be. Highlights: Sal Daher Introduces Raza Shaikh, Founder, Angel & Podcaster “I started angel investing actually on AngelList a bunch of years back and re...

Mar 31, 202147 minSeason 5Ep. 13

Jay Batson - Open Source Dude

Sponsored by Peter Fasse, Patent Attorney at Fish & Richardson: https://www.fr.com/team/j-peter-fasse/ Jay Batson is an angel investor’s angel investor. He’s the kind of guy who people like me, and lots of other people, go to ask really tough questions about angel investing. And, he always has really thoughtful ideas. Whenever I’m puzzling over something, I reach out to Jay. If I can get 10 minutes of his time it’s really precious. I really recommend this relaunch of my first interview with ...

Mar 24, 202145 minSeason 5Ep. 12

Joe Falcão, CFO and Employee #5 at Thrasio

Sponsored by Peter Fasse, Patent Attorney at Fish & Richardson: https://www.fr.com/team/j-peter-fasse/ Joe Falcão is the CFO of Boston-based unicorn Thrasio. Learn the secrets of this uniquely successful startup. Retrace my friend’s exciting journey which started in Kenya and led to Boston via Brazil and other interesting places. Highlights: Sal Daher Introduces Joe Falcão, CFO & #5 Employee at Boston-based Unicorn Thrasio “Always be open to meet people.” “…we are playing within the Amaz...

Mar 17, 202135 minSeason 5Ep. 11

José Falcão, Chefe de Finanças da Thrasio

Patrocinado pelo Peter Fasse, advogado de patentes da Fish & Richardson: https://www.fr.com/team/j-peter-fasse/ José Falcão, Chefe de Finanças da Thrasio explica o que motiva esta companhia que adquire comércios na Amazon.com. Falamos também sobre a jornada de sua vida pela Africa, Asia e o Brasil.

Mar 17, 202128 minSeason 5Ep. 11

Arrigo Bodda, International Angel Investor

Sponsored by Peter Fasse, Prominent Patent Attorney at Fish & Richardson ( https://www.fr.com/team/j-peter-fasse/ ) Growing up in Northern Italy, Arrigo Bodda dreamed of becoming an architect. He chose instead to study law, a handy pre-requisite for a career in human resources in a country where staffing involves a lot of legal work. His corporate career neatly coincided with the emergence of the European Union, a phenomenon that deeply influenced his work and life. After much success in the...

Mar 10, 202152 minSeason 5Ep. 10

Bill Hetzel - Clean Tech Exec and Angel Investor - Startup Success in Maine

Podcast Sponsored by Peter Fasse of Fish & Richardson Dropping prices for solar panels sank many American clean tech companies. PIKA Energy, however, was able to benefit from the trend by innovating. Generac acquired them in 2019 because of their uniquely efficient home energy storage system. Bill Hetzel, former COO, tells the compelling story of this Maine Angel (and Sal)-backed success and more. Highlights: Sal Daher Introduces Bill Hetzel, Clean Tech Exec & Angel Investor “The origina...

Mar 03, 202141 minSeason 5Ep. 9

Peter Fasse, Patent Attorney and Angel Investor - Patents 101

Join Sal Daher's Investment Syndicate: Click to Join Peter Fasse comes from a family of patent attorneys. He is a highly respected partner at Fish & Richardson, the storied Boston-based (now global) firm that represented Alexander Graham Bell, Thomas Edison and the Wright Brothers. Peter’s work continues that tradition by representing some of the leading technological innovators of today. Peter also invests as an angel in technology companies. In this practical and accessible conversation he...

Feb 24, 202156 minSeason 5Ep. 8

Meng Deng, PhD and Karen Wurster - Convert Fat to Cure Diabetes

Join Sal Daher's Investment Syndicate: Click to Join What if an injection could cure your diabetes? Meng Deng, PhD and Karen Wurster were on the podcast to talk about Adipo Therapeutics’ ambitious plan to remake the metabolism of diabetic people. Informative and accessible. Highlights include: Sal Daher Introduces the Founder and the CEO of Adipo Therapeutics “…we're talking about having too much white fat and not enough brown fat.” “…transform that energy-storing white fat into energy-burning b...

Feb 17, 202133 minSeason 5Ep. 7

Frank Ferguson - Practical Dreamer

Join Sal Daher's Investment Syndicate: Click to Joi n Frank Ferguson had a knack for building companies. He headed Bose at a time of rapid growth and built Curriculum Associates into a great success. Frank Ferguson’s angel investing was unusual in that he invested in just a few startups but lavished support on those few. The results were great. Frank was active well into his nineties but passed away recently; this relaunch of an interview I recorded with him is a memorial for his life of achieve...

Feb 10, 20211 hr 11 minSeason 5Ep. 6

Matt Breen, Founder - Rahoo Baby

Join Sal Daher's Investment Syndicate: Click to Join The hardships faced by parents of babies with developmental problems led Matt Breen and his co-founder / fiancée, Erica Costa, both pediatric occupational therapists, to start Rahoo Baby to make it easier for parents to support their baby’s development.Their first product is now at buybuy BABY and Target. A fun chat with a down-to earth founder. Highlights: Sal Daher Introduces Matt Breen, Founder of Rahoo Baby “…how acutely aware parents have...

Feb 03, 202148 minSeason 5Ep. 5

K. Woodman-Maynard - The Business of Being an Artist

Join Sal Daher's Investment Syndicate List: Click to Join Artist K. Woodman-Maynard discusses her gorgeous graphic novel interpretation of The Great Gatsby , the business of being a graphic artist and other engrossing matters. A delightfully different interview with a charming guest. Highlights include: Sal Introduces K. Woodman-Maynard, Creator of The Great Gatsby Graphic Novel “Color is gorgeous. The drawings are extremely expressive and interesting… the style of the period is displayed.” “…I ...

Jan 27, 202140 minSeason 5Ep. 4

Nick Zeckets - Growing Revenue

Join Sal Daher's Investment Syndicate List: Click to Join Founder and revenue consultant Nick Zeckets and I discussed his first startup and what he learned from it. Then we talked about the best ways for startups to build revenues. Instructive and inspiring. Highlights include: Sal Introduces Nick Zeckets, Founder & Revenue Consultant What Quadwrangle Does "What is already out there that I can make better? I don't want to replace it, at least not on day one." “…first and foremost, and I hear...

Jan 27, 202146 minSeason 5Ep. 4

Kristen Overly - Life Science Financing

Join Sal Daher's Investment Syndicate List: Click to Join Kristen Overly works as management consultant and is a leader at MIT Life Science Angels. Kristen and I discussed various aspects of the funding of life science startups. She, like me, is intrigued by the opportunities in what Jeff Behrens called the scrappy biotechs in his doctoral thesis. Highlights include: Sal Daher Introduces Kristen Overly of MIT Life Science Angels & Back Bay Advisors “…MITLifeSciAngels.com. And we look for com...

Jan 20, 202149 minSeason 5Ep. 3

Chuck Donnelly and Julie Morrison - SaaS for Pre-Clinical Trials

Join Sal Daher's Investment Syndicate List: Click to Join RockStep Solutions improves efficiency by 70% according to one client. This is why the startup is getting word of mouth traffic from clients running in vivo drug trials. Founders Chuck Donnelly and Julie Morrison tell their story and share valuable wisdom about this intersection of software and bio. Highlights include: Sal Daher Introduces Chuck Donnelly and Julie Morrison, the Founders of RockStep Solutions RockStep Provides a SaaS Solut...

Jan 13, 202152 minSeason 5Ep. 2

Entrepreneurs Journey - Ham Lord - C Mirabile - Joe Mandato

Join Sal's Investment Syndicate List: Click to Join Launchpad, Boston’s leading angel group, has published a polished collection of stories that illustrate the success and failure of their portfolio companies over two decades. It is titled “The Entrepreneur’s Journey”. Listen to my interview of authors Ham Lord, Christopher Mirabile and Joe Mandato to learn more about this valuable resource for angels and founders. Highlights from the interview: Peter Fasse of Fish & Richardson Sponsors the ...

Jan 06, 202143 minSeason 5Ep. 1

Ham Lord and Christopher Mirabile - Winning Collaboration

Join Sal Daher's Investment Syndicate: Click to Join The collaboration of Ham Lord and Christopher Mirabile, two of Boston’s most consequential super angels, is widely admired. Its most visible fruit is the success of Launchpad Venture Group, which they manage together. In the relaunch of this revealing interview, they let us in on how this winning collaboration came to be and what keeps it productive as it approaches the end of its first decade. Christopher Mirabile and Ham Lord are already fam...

Dec 30, 202056 minSeason 4Ep. 41

Patrick Rivelli, Founder and Angel Investor - How to Invest In Biotech

Join Sal Daher's Investment Syndicate: Click to Join Repeat biotech founder and angel investor Patrick Rivelli talks about his career and about how to approach the daunting challenge of investing in biotech as an angel. Family considerations drove several of Patrick Rivelli’s career choices but did not prevent him from having brilliant triumphs. Success as a consultant was followed by success as an executive. This led him to found his first company and to fund another startup. The most eloquent ...

Dec 09, 20201 hr 14 minSeason 4Ep. 38

Brian Mahon, Investor and Advisor - Expert DOJO

Join Sal Daher's Investment Syndicate: Click to Join Expert Dojo is the international accelerator based in Southern California. Founder Brian Mahon and team look for great founders with profitable businesses that can grow. Brian’s a delightfully articulate guest. Don’t miss this outstanding interview. Highlights: Sal Daher Introduces Brian Mahon of Expert Dojo, the International Accelerator in Southern California “…we’ll invest as easily and as happily in Boston, as we will do in Bosnia…” “…we w...

Dec 02, 20201 hr 6 minSeason 4Ep. 37

Ed Belove, Founder and Angel Investor

Join Sal's Investment Syndicate: Click to Join Ed Belove is a very active angel investor. He's a successful founder in software and hardware. Just a very thoughtful person. Very, very smart, very observant, very committed. Founders would be very lucky to have Ed Belove in their corner. I really enjoyed this interview, which I recorded in the first season of the podcast. And it is a very, very meaty interview. Full of interesting stories. For example, helping build Lotus with Mitch Kapor and all ...

Nov 25, 20201 hr 12 minSeason 4Ep. 36

SQZ's IPO bears out Armon Sharei's vision of empowering cells to change lives.

Join Sal Daher's Investment Syndicate List: Click to Join SQZ's successful IPO validates the vision laid out by Armon Sharei, PhD in this interview recorded two years ago. In accessible language, this genius founder explains the approach that has big strategic players excited. SQZ is the model I have in mind when I invest in biotech companies. Find out why. Armon Sharei wants to train our immune system to fight cancer. We hear a lot of claims like this, however when a mega-pharmaceutical company...

Nov 11, 202046 minSeason 4Ep. 34

Senan Ebrahim, Founder - Hikma Health

The disrupted life of refugees keeps them from having good medical records. Med student Senan Ebrahim decided to do something about it and succeeded. Listen to the story of Hikma Health and of its promising founder. Senan Ebrahim grew up in Silicon Valley but he experienced the Syrian refugee crisis via his grandmother. When he became interested in the problem of refugee health his initial solution was laughably unsuited to real life. Contact with health care workers serving the refugee populati...

Nov 04, 202039 minSeason 4Ep. 33

Beth Marcus - Startup Doc

There's no guest quite like Beth Marcus. She's founded a bunch of companies and has learned tons from it. I recommend this interview to founders and those who are thinking about becoming founders.

Oct 28, 20201 hr 4 minSeason 4Ep. 32

Wade Lange - Startups at Purdue

Join Sal Daher's Investment Syndicate: Click to Join Purdue wants to be Startup U. They are already the #3 university in the US for producing startups, right behind MIT and Columbia. One of my favorite companies, Savran Technologies, came out of Purdue. I spoke with Wade Lange of Purdue Foundry, responsible for promoting startups at Purdue. Several interesting Purdue startups were discussed. Highlights: Sal Daher Welcomes Listeners and Introduces Wade Lange from Purdue Foundry Wade Lange Was Int...

Oct 21, 202036 minSeason 4Ep. 31

Jeff Behrens, PhD - Why You're Wrong About Biotech Funding

Join Sal Daher's Investment Syndicate: Click to Join Jeff Behren's doctoral dissertation suggests that life science startups are not funded the way we all think. Listen to our discussion of his work and learn why he believes we have to revise what is taught to founders about raising money. Highlights: Sal Daher Welcomes Jeff Behrens Back on the Podcast to Discuss His Findings on Biotech Funding “We published papers. We had a world class SAB, and ultimately, we sold these drugs. So, during that, ...

Oct 14, 202041 minSeason 4Ep. 30

Eilon Shalev - Elphi: Hacking Mortgages

Join Sal Daher's Investment Syndicate: Click to Join Mortgage origination is a massive business deeply stuck in the past. Proof: in 2020 it still takes an average of 45 days to approve a mortgage. Israeli founder Eilon Shalev and his buddies from MIT Sloan School aim to change all that with their startup Elphi. Highlights: Sal Daher Welcomes Listeners & Introduces Eilon Shalev of Elphi What Elphi Does The Non-Linearity of Mortgage Applications Is a Huge Problem – Average Time to Approval: 45...

Oct 07, 202036 minSeason 4Ep. 29

Matt Fates, VC & Angel Investor

Join Sal Daher's Investment Syndicate: Click to Join Tech VC Matt Fates of Ascent Venture Partners talks about his portfolio and his investing career and ponders becoming more active as an angel investor. A frank and informative conversation with a delightful guest. Highlights: Sal Daher Welcomes Listeners & Introduces Matt Fates, Venture Capitalist Matt Fate’s VC Portfolio: Connected2Fiber “The power of connectivity is becoming strategic again as most of your software applications reside ou...

Sep 30, 202052 minSeason 4Ep. 28

David Glazer - Biotech Deal Wiz

Join Sal's Investment Syndicate: Click Here Unlike software startups that can scale with minimal resources, biotech startups need frequently to rely on collaborations with big strategic players to get to scale. This is an interview with one of the top attorneys in arranging such deals, David Glazer of Morgan Lewis. I learned much from David; I hope you will too. Highlights: Sal Daher Introduces David Glazer of Morgan Lewis, the Biotech Deal Wiz Why Collaborations with Strategic Partners Are So N...

Sep 23, 202042 minSeason 4Ep. 27

Fred Bamber - Tech VC Becomes an Angel

Join Sal's Investment Syndicate: Click Here As a venture capitalist Fred Bamber helped build such successful companies as Interleaf, Q1 Labs and Volt Server. Now working as an angel investor Fred is invested such exciting companies as SQZ Biotech, Pixability, ViralGains and Streamroot (exited). In his self-effacing and modest way, Fred reveals deep wisdom gained from 75 investments in his career as a VC. Topics include: Fred Bamber Finds His Career Path Avoiding the Military Draft Led Him to Wor...

Sep 16, 20201 hr 11 minSeason 4Ep. 26
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