Moderator: James P. Rathmell, M.D. Participants : Albert Garcia-Casanovas, M.H.A. and Douglas Colquhoun, M.B., M.Sc., M.P.H. Articles Discussed : Association Between Adherence to Patient Blood Management Recommendations and Postoperative Complications in Hip and Knee Arthroplasty Patient Blood Management: Moving Beyond Guidelines to Action Transcript...
Jun 04, 2025•17 min
Moderator: BobbieJean Sweitzer, M.D. Participants : Jessica R Ansari, M.D., M.S. and Craig M. Palmer, M.D. Articles Discussed : Uterine Tone Numeric Rating Score as an Early Indicator of Major Postpartum Hemorrhage During Cesarean Delivery: A Prospective Observational Study Predicting the Unpredictable: A New Approach to Predict Postpartum Hemorrhage from Uterine Atony Transcript...
Jun 02, 2025•41 min
Creator : James P. Rathmell, M.D. July 2025, Volume 143, Issue 1 Overview of July issue original studies. Transcript
Jun 02, 2025•12 min
Moderator: James P. Rathmell, M.D. Participants : Carmen Bozic, M.D. Articles Discussed : Suzetrigine, a Nonopioid NaV1.8 Inhibitor for Treatment of Moderate-to-severe Acute Pain: Two Phase 3 Randomized Clinical Trials Suzetrigine: First in a New Class of Nonopioid Analgesics for Acute Pain Transcript...
May 19, 2025•21 min
Moderator: James P. Rathmell, M.D. Participants : Rebecca L. Wu, M.D. and Max B. Kelz, M.D., Ph.D. Articles Discussed : TAK-925 (danavorexton), an Orexin Receptor 2 Agonist, Reduces Opioid-Induced Respiratory Depression and Sedation Without Affecting Analgesia in Healthy Adult Males Alluring Potential to Accelerate Emergence and Ameliorate Opioid-induced Respiratory Depression without Antagonizing Analgesia: Danavorexton Enters the Anesthetic Landscape Transcript...
May 07, 2025•21 min
Moderator: BobbieJean, M.D. Participants : Douglas Colquhoun, M.B., M.Sc., M.P.H. and Stephan R. Thilen Articles Discussed : Neuromuscular Blockade and Antagonism in Patients with Renal Impairment: A Multicenter Retrospective Cross Sectional Study On and Off Label Use of Sugammadex in Patients with Renal Impairment in the 6 ½ Years Following FDA Approval Transcript...
May 07, 2025•35 min
Creator : James P. Rathmell, M.D., M.B.A. June 2025, Volume 142, Issue 6 Overview of June issue original studies. Transcript
Apr 24, 2025•12 min
Moderator: BobbieJean Sweitzer, M.D. Participants : Daqing Ma, Ph.D. and Kate Leslie, M.B.B.S., M.D. Articles Discussed : Pyridoxine Prevents Postoperative Nausea and Vomiting in Gynecologic Laparoscopic Surgery: A Double-blind Randomized Controlled Trial B6 or Be Sick? Pyridoxine to Prevent Postoperative Nausea and Vomiting Transcript...
Apr 21, 2025•26 min
Moderator: BobbieJean Sweitzer, M.D. Participants : Alessandro Belletti, M.D., and Samuel N. Heyman, M.D. Articles Discussed : Amino Acid Infusion for Kidney Protection in Cardiac Surgery Patients with Chronic Kidney Disease: A Secondary Analysis of the PROTECTION Trial Amino Acid Infusion for the Prevention of Acute Kidney Injury: Yet a Debatable Issue Transcript...
Apr 07, 2025•35 min
Moderator: James P. Rathmell, M.D. Participants : Christopher Connor, M.D., Ph.D. and Peter John Schuller, M.B.B.S., B.Sc. Articles Discussed : Developing an EEG-based model to predict awakening after cardiac arrest using partial processing with the BIS Engine Unlocking Prognostic Potential in the Postarrest Electroencephalogram Transcript...
Apr 07, 2025•29 min
Creator : James P. Rathmell, M.D., M.B.A. May 2025, Volume 142, Issue 5 Overview of May issue original studies.
Apr 04, 2025•12 min
Creator : James P. Rathmell, M.D., M.B.A. April 2025, Volume 142, Issue 4 Overview of April issue original studies.
Mar 21, 2025•13 min
Moderator: James P. Rathmell, M.D. Participants : Yuming Peng, M.D., Ph.D. and Philip Devereaux, M.D., Ph.D. Articles Discussed : Covert Perioperative Strokes in Older Patients Having Noncardiac Surgery (PRECISION): A Prospective Cohort Analysis Perioperative Covert Stroke: Acutely Asymptomatic but Not Benign Transcript...
Mar 04, 2025•18 min
Creator : James P. Rathmell, M.D., M.B.A. March 2025, Volume 142, Issue 3 Overview of March issue original studies.
Feb 19, 2025•11 min
Moderator: BobbieJean Sweitzer, M.D. Participants : Jai Darvall, Ph.D. and Tong J. Gan, M.D., M.B.A., M.H.S. Articles Discussed : Chewing Gum to Treat Postoperative Nausea and Vomiting in Female Patients: A Multicenter Randomized Trial Chewing Gum: A Viable Option as a Rescue Therapy for Postoperative Nausea and Vomiting? Transcript...
Feb 11, 2025•36 min
Moderator: James P. Rathmell, M.D. Participants : James Hitt, M.D., Ph.D. and Mark C Bicket, M.D., Ph.D. Articles Discussed : Continuation versus Interruption of Buprenorphine/Naloxone in Adult Veterans Undergoing Surgery: Examination of Postoperative Pain and Opioid Utilization in a National Retrospective Cohort Study Building a Better Base for Keeping Buprenorphine on Board for Surgery Transcript...
Jan 29, 2025•27 min
Moderator: BobbieJean Sweitzer, M.D. Participants : Annie Xin, Ph.D., M.D. and Randall Flick, M.D., M.P.H. Articles Discussed : Neurodevelopmental Outcomes After Multiple General Anaesthetic Exposure Before Five Years Of Age – A Cohort Study Secondary Analyses: The Perils of Making Do Transcript...
Jan 28, 2025•34 min
Creator : James P. Rathmell, M.D., M.B.A. February 2025, Volume 142, Issue 2 Overview of February issue original studies. Transcript
Jan 17, 2025•10 min
Creator : James P. Rathmell, M.D., M.B.A. January 2025, Volume 142, Issue 1 Overview of January issue original studies.
Dec 19, 2024•11 min
Moderator: BobbieJean Sweitzer, M.D. Participants : Guido Mazzinari, M.D., Ph.D., M.Sc. and Snehalata Huzurbazar, Ph.D. Articles Discussed : High Positive End-expiratory Pressure (PEEP) with Recruitment Maneuvers versus Low PEEP during General Anesthesia for Surgery: A Bayesian Individual Patient Data Meta-analysis of Three Randomized Clinical Trials Bayesian Analyses Are Appearing and Are Welcome Transcript...
Dec 10, 2024•51 min
Moderator: James P. Rathmell, M.D. Participants : Nicholas Joseph Douville, M.D., Ph.D. and Vesela P. Kovacheva, M.D., Ph.D. Articles Discussed : Polygenic Score for the Prediction of Postoperative Nausea and Vomiting: A Retrospective Derivation and Validation Cohort Study Polygenic Risk Scores: Coming to Your Operating Room? Transcript...
Dec 10, 2024•28 min
Creator : James P. Rathmell, M.D., M.B.A. December 2024, Volume 141, Issue 6 Overview of December issue original studies. Transcript
Nov 11, 2024•13 min
Moderator: BobbieJean Sweitzer, M.D. Participants : Anil Panigrahi, M.D., Ph.D. Articles Discussed : Factor Eight Inhibitor Bypass Activity Use in Cardiac Surgery: A Propensity Matched Analysis of Safety Outcomes Transcript...
Nov 11, 2024•20 min
Moderator: James P. Rathmell, M.D. Participants : Rodney Gabriel, M.D. Articles Discussed : Paravertebral versus Pectoralis-II (Interpectoral and Pectoserratus) Nerve Blocks for Postoperative Analgesia after Non-Mastectomy Breast Surgery: A Randomized, Controlled, Observer-Masked Noninferiority Trial Transcript...
Nov 11, 2024•15 min
Moderator: James P. Rathmell, M.D. Participants : Paul S. Myles, M.B., B.S., M.P.H., M.D., D.Sc. and Daniel I. McIsaac, M.D., M.P.H. Articles Discussed : Dexamethasone for Cardiac Surgery: A Practice Preference-Randomized Consent Comparative Effectiveness Trial Routine Innovation in Perioperative Clinical Trials: The Best Chance to Answer Our Most Important Questions? Transcript...
Nov 05, 2024•26 min
Creator : James P. Rathmell, M.D., M.B.A. November 2024, Volume 141, Issue 5 Overview of November issue original studies. Transcript
Oct 16, 2024•11 min
Moderator: BobbieJean Sweitzer, M.D. Participants : Karim Brohi, M.D. and Richard P. Dutton, M.D., M.B.A. Articles Discussed : Correction of Trauma-induced Coagulopathy by Goal-directed Therapy: A Secondary Analysis of the ITACTIC Trial Tactics versus Strategy in Trauma Resuscitation Transcript...
Oct 08, 2024•33 min
Moderator: James P. Rathmell, M.D. Participants : Daniele De Luca M.D., Ph.D. and David Tingay, M.B.B.S., Ph.D. Articles Discussed : Global and Regional Heterogeneity of Lung Aeration in Neonates with Different Respiratory Disorders: A Physiological, Observational Study Lung Ultrasound and Regional Heterogeneity: A Bedside Solution to an Under-Recognized Problem? Transcript...
Sep 24, 2024•21 min
Creator : James P. Rathmell, M.D., M.B.A. October 2024, Volume 141, Issue 4 Overview of October issue original studies. Transcript
Sep 19, 2024•14 min
Moderator: BobbieJean Sweitzer, M.D. Participants : Sebastian J. Corlette, M.B.B.S. and Isabelle Constant, Ph.D., M.D. Articles Discussed : Changes in the Term Neonatal Electroencephalogram with General Anesthesia – A Systematic Review with Narrative Synthesis Challenge of Neonatal Anesthesia: Which Optimal EEG Target? Transcript...
Sep 16, 2024•45 min