Cannabis Nutrigenomics: How Your Genes Affect Your High | David Krantz ~ ATTMind 111

Adventures Through The Mind

Nov 22, 2019•1 hr 19 min•Ep. 111

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Episode description

David Krantz and I talk about how genetics affect the metabolism of cannabis (nutrigenomics) and the resulting impact of cannabis use on our epigenetic health. Furthermore, we reach into a discussion on how the same framework of understanding applies to our metabolism of psychedelics and the potential future of a genome-specific screening program for psychedelic-assisted psychotherapy.

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Newsletter: https://www.jameswjesso.com/newsletter ------------- Episode Breakdown

a general rundown of nutritional genomics and its application in understanding biology
the profound health issues David faced that brought him into nutritional genomics
(special note about the value of understanding polyvagal theory)
the failure of the pre-packed dietary approach, be it veganism, paleo, or low-carb
the endocannabinoid system
the genetic differences of cannabis metabolism between different people
why some people can “smoke weed every day” and make millions, and others can’t get off the couch
how cannabis effects working memory differently in different genetic predispositions in each people based on baseline dopamine levels
how our brain hides from itself
the phenomena of “used to smoke all the time without issues then all of a sudden cannabis creates anxiety and paranoia”
epigenetics and how cannabis changes how our genes express
the genetic variant that increases the chances of developing cannabis-induced psychosis
genetic profiling as a screening platform to understand what medical intervention would be most helpful for specific people
the institutional complications that might prevent the introduction of genetic-specific medical care into the medical infrastructure
how these ideas fit inside the modern context of the climate crisis
how do genetic profiles influence dose-response differences with psychedelics
speculating on the long term epigenetic impact of psilocybin use
speculating on the long term epigenetic impact of therapeutic/healing work

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